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Scientific Reports (10)
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Showing 1–24 of 24 results

Advanced filters: Author: Pablo Alcon Clear advanced filters

Effectiveness of enoxaparin in preventing intraoperative fibrin formation during DMEK assessed in a before-and-after study

Pablo De-Arriba-Palomero
David Mingo-Botín
Francisco Arnalich-Montiel
ResearchOpen Access02 May 2025
Scientific Reports

Volume: 15, P: 1-8
Inducing cylindrical and spherical defocus after implantation with new generation intraocular lenses improves intermediate and near visual acuity

Naren Shetty
Rohit Shetty
Abhijit Sinha Roy
ResearchOpen Access30 Dec 2024
Scientific Reports

Volume: 14, P: 1-11
Author Correction: FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions

Pablo Alcón
Artur P. Kaczmarczyk
Lori A. Passmore
Amendments and CorrectionsOpen Access17 Feb 2025
Nature

Volume: 639, P: E2
Two-dimensional Peripheral Refraction and Retinal Image Quality in Emmetropic Children

Weizhong Lan
Zhenghua Lin
Pablo Artal
ResearchOpen Access07 Nov 2019
Scientific Reports

Volume: 9, P: 1-9
Erratum: Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

Stefano Stella
Pablo Alcón
Guillermo Montoya
Amendments and Corrections05 Jul 2017
Nature

Volume: 547, P: 476
Brolucizumab clinical and safety outcomes in a neovascular age-related macular degeneration national database: Fight Retinal Blindness Spain (FRB Spain)

Javier Zarranz-Ventura
Sonia Marías-Pérez
Lucia Miguel-Escuder
Research05 Jun 2025
Eye

P: 1-8
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

Sijacki et al. show how phosphorylation of FANCI by the ATR DNA damage kinase primes the FANCD2–FANCI clamp for ubiquitination. Phosphorylation promotes closure of the clamp, exposing a lysine for ubiquitination to initiate DNA cross-link repair.

Tamara Sijacki
Pablo Alcón
Lori A. Passmore
Research01 Sept 2022
Nature Structural & Molecular Biology

Volume: 29, P: 881-890
FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Structural analysis of the DNA crosslink repair factors FANCD2 and FANCI demonstrates that a complex of both factors adopts a closed conformation upon ubiquitination of FANCD2, trapping the complex on DNA.

Pablo Alcón
Shabih Shakeel
Lori A. Passmore
Research17 Feb 2020
Nature Structural & Molecular Biology

Volume: 27, P: 240-248
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions

FANCD2–FANCI is a sliding clamp that diffuses on double-stranded DNA but stalls when it reaches a single-stranded gap, providing a unified molecular mechanism that reconciles the roles of FANCD2–FANCI in the recognition and protection of stalled replication forks.

Pablo Alcón
Artur P. Kaczmarczyk
Lori A. Passmore
ResearchOpen Access31 Jul 2024
Nature

Volume: 632, P: 1165-1173
Structure of the Fanconi anaemia monoubiquitin ligase complex

The structure of the multiprotein Fanconi anaemia core complex, determined using cryo-electron microscopy and mass spectrometry, shows that the complex adopts an extended asymmetric structure and highlights the structural and functional asymmetry of the RING finger domains.

Shabih Shakeel
Eeson Rajendra
Lori A. Passmore
Research30 Oct 2019
Nature

Volume: 575, P: 234-237
Fourier tools for the evaluation of refractive multifocal designs

Pablo De Gracia
ResearchOpen Access19 Dec 2023
Scientific Reports

Volume: 13, P: 1-12
The histone chaperone SPT2 regulates chromatin structure and function in Metazoa

Using a combination of bioinformatics, biochemistry, genetics, genomics and cell-based approaches, this study shows that the H3–H4 binding capacity of the histone chaperone SPT2 is required to preserve chromatin structure and function in Metazoa.

Giulia Saredi
Francesco N. Carelli
John Rouse
ResearchOpen Access18 Jan 2024
Nature Structural & Molecular Biology

Volume: 31, P: 523-535
Ray tracing optimization: a new method for intraocular lens power calculation in regular and irregular corneas

Pablo Pérez-Merino
Jaime Aramberri
Jos J. Rozema
ResearchOpen Access20 Mar 2023
Scientific Reports

Volume: 13, P: 1-11
The influence of peripheral vision on driving performance in patients implanted with an inverted meniscus intraocular lens

Miriam Casares-López
Sonia Ortiz-Peregrina
Pablo Artal
ResearchOpen Access21 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

The structure of Cpf1, a CRISPR–Cas/RNA-guided nuclease, is presented with a three-stranded RNA–DNA loop after cleavage, providing insight into its working mechanism.

Stefano Stella
Pablo Alcón
Guillermo Montoya
Research31 May 2017
Nature

Volume: 546, P: 559-563
Involvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury

Francisco M. Nadal-Nicolás
Caridad Galindo-Romero
Marta Agudo-Barriuso
ResearchOpen Access08 Dec 2016
Scientific Reports

Volume: 6, P: 1-14
A phase III study comparing preservative-free latanoprost eye drop emulsion with preserved latanoprost in open-angle glaucoma or ocular hypertension

Christophe Baudouin
Ingeborg Stalmans
Francesca Cordeiro
ResearchOpen Access25 Feb 2025
Eye

Volume: 39, P: 1599-1607
Class 2 CRISPR–Cas RNA-guided endonucleases: Swiss Army knives of genome editing

This review highlights recent mechanistic insights into the CRISPR class 2 type V enzymes Cpf1 and C2c1, which are crucial for improving these genome engineering tools and expanding the genomic editing space.

Stefano Stella
Pablo Alcón
Guillermo Montoya
Reviews16 Oct 2017
Nature Structural & Molecular Biology

Volume: 24, P: 882-892
Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease

Esther Gramage
Jorge Sáiz
Gonzalo Herradón
ResearchOpen Access04 Mar 2022
Scientific Reports

Volume: 12, P: 1-16
Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication

Rosalía Fernández-Calle
Milagros Galán-Llario
Gonzalo Herradón
ResearchOpen Access20 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Optic nerve head changes in early glaucoma: a comparison between stereophotography and Heidelberg retina tomography

L E Pablo
A Ferreras
A B Pajarin
Research13 Feb 2009
Eye

Volume: 24, P: 123-130
Molecular architecture of the Jumonji C family histone demethylase KDM5B

Jerzy Dorosz
Line Hyltoft Kristensen
Michael Gajhede
ResearchOpen Access11 Mar 2019
Scientific Reports

Volume: 9, P: 1-13
Social media and smartphone app use predicts maintenance of physical activity during Covid-19 enforced isolation in psychiatric outpatients

Agnes Norbury
Shelley H. Liu
M. Mercedes Perez-Rodriguez
Research14 Dec 2020
Molecular Psychiatry

Volume: 26, P: 3920-3930
Long-term outcomes of neovascular glaucoma treated with and without intravitreal bevacizumab

L C Olmos
M S Sayed
R K Lee
Research18 Dec 2015
Eye

Volume: 30, P: 463-472