Nature Search

The CXC Chemokine GCP-2/CXCL6 Is Predominantly Induced in Mesenchymal Cells by Interleukin-1β and Is Down-Regulated by Interferon-γ: Comparison with Interleukin-8/CXCL8

Anja Wuyts
Sofie Struyf
Jo Van Damme
Research01 Jan 2003
Laboratory Investigation

Volume: 83, P: 23-34
Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours

In a mouse model of mammary carcinoma, loss of deleted in colorectal cancer (DCC) promotes metastasis formation, and in cell cultures derived from p53-deficient mouse mammary tumours DCC expression controls netrin-1-dependent cell survival, supporting the function of DCC as a context-dependent tumour suppressor that limits survival of disseminated tumour cells.

Paul Krimpenfort
Ji-Ying Song
Anton Berns
Research22 Feb 2012
Nature

Volume: 482, P: 538-541
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

A cross-sectional analysis of participants in the MetaCardis Body Mass Index Spectrum cohort finds that the higher prevalence of gut microbiota dysbiosis in individuals with obesity is not observed in those who take statin drugs.

Sara Vieira-Silva
Gwen Falony
Jeroen Raes
Research06 May 2020
Nature

Volume: 581, P: 310-315
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

A biobank of ovarian cancer organoids recapitulates the histopathological and molecular hallmarks of patient tumors and provides a resource for preclinical research.

Oded Kopper
Chris J. de Witte
Hans Clevers
Research22 Apr 2019
Nature Medicine

Volume: 25, P: 838-849
The Medicago genome provides insight into the evolution of rhizobial symbioses

Sequencing of Medicago truncatula, a model organism of legume biology, shows that genome duplications had a role in the evolution of endosymbiotic nitrogen fixation.

Nevin D. Young
Frédéric Debellé
Bruce A. Roe
ResearchOpen Access16 Nov 2011
Nature

Volume: 480, P: 520-524
SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo

Combined inhibition of SHP2 and MEK is an effective therapeutic approach in non-small-cell lung cancer.

Sara Mainardi
Antonio Mulero-Sánchez
Rene Bernards
Research28 May 2018
Nature Medicine

Volume: 24, P: 961-967
Matrix metalloproteinases in arthritis: towards precision medicine

Matrix metalloproteinases contribute to irreversible joint remodelling in the pathogenesis of joint diseases, including rheumatoid arthritis and osteoarthritis. This article reviews several aspects of matrix metalloproteinase biology related to arthritis and discusses how they relate to opportunities for precision medicine and diagnosis.

Bernard Grillet
Rafaela Vaz Sousa Pereira
Ghislain Opdenakker
Reviews09 May 2023
Nature Reviews Rheumatology

Volume: 19, P: 363-377
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

Els Wauters
Pierre Van Mol
Diether Lambrechts
ResearchOpen Access21 Jan 2021
Cell Research

Volume: 31, P: 272-290
Beyond sodefrin: evidence for a multi-component pheromone system in the model newt Cynops pyrrhogaster (Salamandridae)

Ines Van Bocxlaer
Margo Maex
Franky Bossuyt
ResearchOpen Access03 Mar 2016
Scientific Reports

Volume: 6, P: 1-9
Courtship Pheromone Use in a Model Urodele, the Mexican Axolotl (Ambystoma mexicanum)

Margo Maex
Ines Van Bocxlaer
Franky Bossuyt
ResearchOpen Access04 Feb 2016
Scientific Reports

Volume: 6, P: 1-9
TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis

Tamara Loos
Lies Dekeyzer
Paul Proost
Research17 Jul 2006
Laboratory Investigation

Volume: 86, P: 902-916
The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention

Seppe Cambier
Mieke Gouwy
Paul Proost
ReviewsOpen Access01 Feb 2023
Cellular & Molecular Immunology

Volume: 20, P: 217-251
Neutrophil chemoattractant receptors in health and disease: double-edged swords

Mieke Metzemaekers
Mieke Gouwy
Paul Proost
Reviews01 Apr 2020
Cellular & Molecular Immunology

Volume: 17, P: 433-450
Neutrophils: a cornerstone of liver ischemia and reperfusion injury

Thiago Henrique Caldeira de Oliveira
Pedro Elias Marques
Mauro Martins M Teixeira
Reviews18 Sept 2017
Laboratory Investigation

Volume: 98, P: 51-62
The unique structural and functional features of CXCL12

Rik Janssens
Sofie Struyf
Paul Proost
Reviews30 Oct 2017
Cellular & Molecular Immunology

Volume: 15, P: 299-311

Search

The CXC Chemokine GCP-2/CXCL6 Is Predominantly Induced in Mesenchymal Cells by Interleukin-1β and Is Down-Regulated by Interferon-γ: Comparison with Interleukin-8/CXCL8

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

The Medicago genome provides insight into the evolution of rhizobial symbioses

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo

Matrix metalloproteinases in arthritis: towards precision medicine

Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

Beyond sodefrin: evidence for a multi-component pheromone system in the model newt Cynops pyrrhogaster (Salamandridae)

Courtship Pheromone Use in a Model Urodele, the Mexican Axolotl (Ambystoma mexicanum)

TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis

The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention

Neutrophil chemoattractant receptors in health and disease: double-edged swords

Neutrophils: a cornerstone of liver ischemia and reperfusion injury

The unique structural and functional features of CXCL12

Search

Quick links

Search

Filter By:

Search

Quick links