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Pulse enhanced weathering of trans-Gondwanan super mountains during the Ediacaran Shuram carbon isotope excursion, potentially increased nutrient inputs in the ocean which resulted in transient oceanic oxygenation, according to dynamic box modeling, geochemistry data, and Li isotope composition analysis of carbonate Ediacaran sections in south China.

Detecting dilute airborne biomarkers is important in healthcare but is limited by the low sensitivity of current gas sensors. A portable, low-cost device is introduced that uses water condensation to enrich airborne biomarkers into a concentrated liquid, enabling existing liquid sensors to detect biomarkers with high sensitivity and broad accessibility.

The energy disorders in the lateral direction of the junction in large-area photovoltaic modules are largely overlooked. Here, authors employ organic amidinium passivators to suppress the micro-inhomogeneity in the lateral energy landscapes and achieve high performance stable perovskite solar cells.

A nanoporous photocatalyst producing low levels of hydrogen peroxide is shown to modulate intracellular stress granules, enhancing resilience against oxidative stress and providing cardioprotection in an ex vivo rodent model of myocardial ischaemia–reperfusion injury.

Acetylene hydrochlorination is an industrially important reaction but is, in many instances, still catalyzed by mercury chloride. Here, the authors report a nanocomposite of pyrrolic nitrogen-doped carbon capable of activating acetylene, which also exhibits promising performance in vinyl chloride formation.

The black phase of formamidinium lead iodide perovskite is used to make highly efficient solar cells, and a technique to improve its purity and stability by controlling crystal nucleation could make them even better.

The power conversion efficiencies of thick-film perovskite solar cells lag behind those with nanometre film thickness. Here, the authors rule out the restrictions of carrier lifetime on device performance and reveal the critical role of lattice strain in micron-scale thick perovskite films.

Perovskite solar cells often rely on ordered molecular contacts for favourable charge-carrier transport, and any organizational disruption reduces device efficiency. Now a contact featuring an orthogonal π-skeleton has been shown to afford a high resilience to external stimuli plus long-term durability in accelerated-ageing tests.

Nanozymes offer diverse therapeutic avenues for cancer treatment. In this work, the authors report an iron-based quasi-metal organic framework nanozyme Q-MIL-53(Fe) with enhanced peroxidase and catalase-mimicking activity and glutathione depletion capacity and use it for tumor immunotherapy via inducing ferroptosis and immunogenic cell death.

Precipitation impacts leaf senescence. Here, the authors use carbon flux and satellite data to demonstrate that reduced precipitation frequency is associated with a faster drought response in trees and show that Earth system models don’t capture the impact of reduced precipitation.

The FarmGTEx Project aims to understand genetic control of gene activity under diverse biological and environmental contexts in domestic animals, providing a foundation for improving animal precision breeding, adaptation and human health.

The pilot phase of PigGTEx, re-analyzing 5,457 published RNA-seq samples, presents a pan-tissue catalog of molecular quantitative trait loci. Cross-species comparisons identify traits with shared genetic regulation in humans.

High spatiotemporal resolution is essential for next-generation bioelectronics, enabling precise biological monitoring and control. This Review highlights recent advances in electrical, electrochemical and optoelectronic devices, discussing key materials, architectures and strategies to enhance resolution and address critical biomedical challenges.

The clinical outcomes of esophageal squamous cell carcinoma (ESCC) remain poor, and thus it remains critical to find prognostic molecular markers. Here, the authors identify prognostic ESCC subtypes based on bulk and single-cell RNA-seq combined with histology AI in samples from patients with more than four years of follow-up, and find markers associated with immune evasion.

A wireless electronic capsule — which is engineered for ingestion and has a sensing ribbon that conforms to the shape of the stomach — can provide non-invasive and long-term tracking of gastric electrophysiological signals.

Microfabrication has an essential role in device fabrication but is accompanied by unfavourable environmental footprint. This study presents a bioinspired permeable junction approach for sustainable microfabrication, which eliminates the use of hazardous chemicals and minimizes energy consumption.

The IFITM3 innate immunity protein directly binds presenilin near the active site and upregulates γ-secretase activity and the production of amyloid-β, and IFITM3 is upregulated in patients with late-onset Alzheimer’s disease.

Ion migration has a detrimental effect on the performance and stability of halide perovskite optoelectronics. Here, the authors incorporated a small dosage of high-valence neodymium cation to suppress this, with a minimal impact on the lattice microstrain.

A silicon-based electrode system is described that allows tunable spatiotemporal photostimulation of cardiac systems, with the optoelectronic capabilities of these devices being demonstrated in mouse, rat and pig heart models.

A peri-fused polyaromatic core structure is used to produce a relatively chemically inert and structurally rigid molecular contact that improves the efficiency and durability of perovskite solar cells.

Developing biointerfaces that combine the advantages of both monolithic and focal elements remains challenging. Now, a hydrogel that releases surface-modified granules and shows biointerface transition capability has been developed. This granule-releasing hydrogel manages colitis, accelerates wound healing, and facilitates cardiac tissue regeneration and mapping of cardiac activity with bioelectronic devices.

Transition metal chalcogenides are effective and economical electrocatalysts for the hydrogen evolution reaction in alkaline media, yet active sites and catalytic mechanisms remain unclear. Here the authors use operando spectroscopy to study the in-situ conversion of NiS to highly active Ni₃S₂/NiO dual-site catalysts for the alkaline hydrogen evolution reaction.

High-entropy hybrid perovskites exhibit improved materials properties compared with their individual components. When employed in solar cells, champion devices achieve a certified power conversion efficiency of 25.5% and an extrapolated T₉₀ lifetime of over 5,000 h under continuous light soaking.

Fabrication of semiconductor heterojunctions typically involves a complex process and often leads to bioincompatibility. Here, the authors propose a porous heterojunction in p-type silicon via simple stain etching at ambient conditions, and apply it in optically induced biomodulation.

Achieving a circular system for electronics hinges on greener design and effective recycling methods. Now, research presents a more durable printed circuit board that can also be sustainably and effectively recycled.

Electroceuticals apply electrical or electrochemical signals to regulate physiological functions. This Review explores (photo)electrochemical modulation in implantable electroceuticals, highlighting energy conversion principles and device designs for the remote control of biological systems.

Single-site pincer-ligated iridium complexes exhibit the ability for C-H activation but suffer from instability and difficulty in catalyst recycling. Here the authors design an atomically dispersed Ir catalyst which can be considered the bridge between homogeneous and heterogeneous catalysis and displays an outstanding catalytic performance in n-butane dehydrogenation.

Interleukin-12 (IL-12) is a potent immunotherapeutic agent.

Precisely strained graphene layers can enable observation of periodic pseudo-magnetic fields with high symmetry. Here, the authors report experimental tuning of large area periodic pseudo-magnetic fields within twisted bilayer graphene and massive Dirac electrons having circularly localized pseudo-Landau levels.

A catalog of over 3 million transposable elements in pigs reveals that evolutionarily young SINEs are associated with increased epigenomic silencing, and may be related to expression of nearby genes.