Nature Search

A new petunia flower colour generated by transformation of a mutant with a maize gene

Peter Meyer
Iris Heidmann
Heinz Saedler
Research23 Dec 1987
Nature

Volume: 330, P: 677-678
The effect of neurodegenerative diseases on the subventricular zone

The subventricular zone (SVZ) is the major source of proliferative cells in the adult brain. In this Review, Curtis, Faull and Eriksson describe how the SVZ responds to neurodegenerative disease and discuss possible therapeutic strategies to harness its neurogenic potential.

Maurice A. Curtis
Richard L. M. Faull
Peter S. Eriksson
Reviews01 Sept 2007
Nature Reviews Neuroscience

Volume: 8, P: 712-723
“Gravars”

PETER KAFKA
Research02 May 1970
Nature

Volume: 226, P: 436-439
Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Nicolás Herranz
Suchira Gallage
Jesús Gil
Amendments and Corrections22 May 2024
Nature Cell Biology

Volume: 26, P: 1019
Decoding chromatin states by proteomic profiling of nucleosome readers

A multidimensional proteomics analysis of the interactions between around 2,000 nuclear proteins and over 80 modified dinucleosomes representing promoter, enhancer and heterochromatin states provides insights into how chromatin states are decoded by chromatin readers.

Saulius Lukauskas
Andrey Tvardovskiy
Till Bartke
ResearchOpen Access06 Mar 2024
Nature

Volume: 627, P: 671-679
Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Nicolás Herranz
Suchira Gallage
Jesús Gil
Amendments and Corrections30 Sept 2015
Nature Cell Biology

Volume: 17, P: 1370
In Situ Activation of Human Erythrocyte Prolidase: Potential for Enzyme Replacement Therapy in Prolidase Deficiency

Peter Hechtman
Andrea Richter
Yi-Mun Leong
Research01 Dec 1988
Pediatric Research

Volume: 24, P: 709-712
Author Correction: Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization

Emma Nolan
Victoria Louise Bridgeman
Ilaria Malanchi
Amendments and Corrections04 Apr 2022
Nature Cancer

Volume: 3, P: 519
Author Correction: Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

Nuria Ferrandiz
Consuelo Barroso
Enrique Martinez-Perez
Amendments and CorrectionsOpen Access29 Aug 2018
Nature Communications

Volume: 9, P: 1
Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate

Silvia A. Ferreira
Meghna S. Motwani
Eileen Gentleman
Amendments and CorrectionsOpen Access14 Nov 2018
Nature Communications

Volume: 9, P: 1
Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers

Saulius Lukauskas
Andrey Tvardovskiy
Till Bartke
Amendments and CorrectionsOpen Access09 Apr 2024
Nature

Volume: 628, P: E6
Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization

Malanchi and colleagues demonstrate that irradiation in healthy lung tissue leads to an alveolar repair response orchestrated by neutrophils and Notch signaling that promotes metastatic colonization of disseminated tumor cells in the lung.

Emma Nolan
Victoria Louise Bridgeman
Ilaria Malanchi
Research24 Feb 2022
Nature Cancer

Volume: 3, P: 173-187
Isolation of highly enriched primary human microglia for functional studies

Justin Rustenhoven
Thomas I-H Park
Mike Dragunow
ResearchOpen Access18 Jan 2016
Scientific Reports

Volume: 6, P: 1-11
Prolidase Deficiency in Cultured Human Fibroblasts: Biochemical Pathology and Iminodipeptide-Enhanced Growth

Michael Dolenga
Peter Hechtman
Research01 Oct 1992
Pediatric Research

Volume: 32, P: 479-482
Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

During meiosis, step-wise release of sister chromatid cohesion mediated by REC-8 cohesin is required for the formation of haploid gametes. Here, the authors show that in C. elegans oocytes, regulated recruitment of Aurora B kinase ensures the correct distribution of REC-8 phosphorylation, which promotes cohesion release.

Nuria Ferrandiz
Consuelo Barroso
Enrique Martinez-Perez
ResearchOpen Access26 Feb 2018
Nature Communications

Volume: 9, P: 1-16
Bi-directional cell-pericellular matrix interactions direct stem cell fate

3D hydrogels have provided information on the physical requirements of stem cell fate, but the contribution of interactions with the pericellular environment are under-explored. Here the authors show that pericellular matrix secreted by human bone marrow stromal cells (hMSC) embedded in a HA-based hydrogel contribute to hMSC fate.

Silvia A. Ferreira
Meghna S. Motwani
Eileen Gentleman
ResearchOpen Access03 Oct 2018
Nature Communications

Volume: 9, P: 1-12
Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate

Silvia A. Ferreira
Meghna S. Motwani
Eileen Gentleman
Amendments and CorrectionsOpen Access18 Dec 2018
Nature Communications

Volume: 9, P: 1
Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

Xianjun Dong
Zhixiang Liao
Clemens R. Scherzer
Amendments and Corrections17 Dec 2018
Nature Neuroscience

Volume: 22, P: 144-147
ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways

Leukemic cells depend on the nucleotide synthesis pathway to proliferate. Here the authors use metabolomics and proteomics to show that inhibition of ATR reduced the activity of these pathways thus providing a valuable therapeutic target in leukemia.

Thuc M. Le
Soumya Poddar
Caius G. Radu
ResearchOpen Access14 Aug 2017
Nature Communications

Volume: 8, P: 1-14
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Gil and colleagues report that mTOR affects the tumour-related effects of the senescence-associated secretory phenotype (SASP), by inhibiting the translation of the MAPKAPK2 kinase and thereby preventing the ZFP36L1-mediated SASP mRNA decay.

Nicolás Herranz
Suchira Gallage
Jesús Gil
Research17 Aug 2015
Nature Cell Biology

Volume: 17, P: 1205-1217
H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

Nakamura et al. show that DNA repair pathway choice and initiation of homologous recombination is guided by the recruitment of BRCA1 to post-replicative chromatin by BARD1 recognition of histone H4 tails unmethylated on lysine 20.

Kyosuke Nakamura
Giulia Saredi
Anja Groth
Research25 Feb 2019
Nature Cell Biology

Volume: 21, P: 311-318
Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

The BRAINcode consortium found that tens of thousands of transcribed noncoding elements (TNEs) from the ‘dark matter’ of our genome are active in dopamine neurons. They may be linked to schizophrenia, Parkinson’s disease, and addiction.

Xianjun Dong
Zhixiang Liao
Clemens R. Scherzer
Research17 Sept 2018
Nature Neuroscience

Volume: 21, P: 1482-1492
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma

Combined inhibition of oncogene-driven glucose uptake and induction of cytoplasmic-p53 activity induces apoptosis in a subset of glioblastoma samples. In mice, PET imaging of glucose uptake predicts glioblastoma response to this combination therapy.

Wilson X Mai
Laura Gosa
David A Nathanson
Research09 Oct 2017
Nature Medicine

Volume: 23, P: 1342-1351
Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure

In a first step toward developing autologous tissue grafts for the treatment of children with intestinal failure, patient-derived jejunal organoids seeded on scaffolds of decellularized human intestinal matrix formed grafts that had jejunal properties and formed luminal structures when transplanted into mice.

Laween Meran
Isobel Massie
Vivian S. W. Li
Research07 Sept 2020
Nature Medicine

Volume: 26, P: 1593-1601
Flunarizine, a Calcium Channel Antagonist, Is Partially Prophylactically Neuroprotective in Hypoxic-Ischemic Encephalopathy in the Fetal Sheep

Alistair J Gunn
Christopher E Williams
Peter D Gluckman
Research01 Jun 1994
Pediatric Research

Volume: 35, P: 657-663
Novel Cues Reinstate Cocaine-Seeking Behavior and Induce Fos Protein Expression as Effectively as Conditioned Cues

Ryan M Bastle
Peter R Kufahl
Janet L Neisewander
Research25 Apr 2012
Neuropsychopharmacology

Volume: 37, P: 2109-2120
Pericytes take up and degrade α-synuclein but succumb to apoptosis under cellular stress

Taylor J. Stevenson
Rebecca H. Johnson
Michael Dragunow
ResearchOpen Access15 Oct 2022
Scientific Reports

Volume: 12, P: 1-17
Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease

Smyth et al. use tissue microarrays from Alzheimer’s disease (AD) patient brains to show that PDGF-BB:PDGFRβ signalling components are reduced in AD. They then use primary human brain pericytes to elucidate a pathway by which PDGF-BB:PDGFRβ signalling in brain pericytes is disrupted in AD, thus impairing the blood brain barrier.

Leon C. D. Smyth
Blake Highet
Mike Dragunow
ResearchOpen Access17 Mar 2022
Communications Biology

Volume: 5, P: 1-16
Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

Jansson et al. design a high content screening system to target inflammation in human brain cells of the blood–brain barrier (pericytes and endothelial cells) to identify inflammatory modifiers. They identify cardiac glycosides as powerful regulators of neuroinflammatory pathways in brain barrier tissues such as vasculature, meninges and choroid plexus.

Deidre Jansson
Victor Birger Dieriks
Mike Dragunow
ResearchOpen Access26 Feb 2021
Communications Biology

Volume: 4, P: 1-17
Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression

Thomas I-H. Park
Vaughan Feisst
Mike Dragunow
ResearchOpen Access24 May 2016
Scientific Reports

Volume: 6, P: 1-17
An anti-inflammatory role for C/EBPδ in human brain pericytes

Justin Rustenhoven
Emma L. Scotter
Mike Dragunow
ResearchOpen Access13 Jul 2015
Scientific Reports

Volume: 5, P: 1-14
Routine culture and study of adult human brain cells from neurosurgical specimens

The authors describe how to establish dissociated cultures of neurons, astrocytes, microglia, pericytes, and brain endothelial and neural precursor cells, as well as explant cultures of the leptomeninges, cortical slice cultures and brain tumor cells.

Thomas I.-H. Park
Leon C. D. Smyth
Mike Dragunow
Protocols12 Jan 2022
Nature Protocols

Volume: 17, P: 190-221
Optimal scheduling to reduce morbidity of involved field radiotherapy with transplantation for lymphomas: A Prospective Australasian Leukaemia and Lymphoma Group Study

A Wirth
H M Prince
S Davis
Research22 Nov 2004
Bone Marrow Transplantation

Volume: 35, P: 291-298

Search

A new petunia flower colour generated by transformation of a mutant with a maize gene

The effect of neurodegenerative diseases on the subventricular zone

“Gravars”

Author Correction: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

Decoding chromatin states by proteomic profiling of nucleosome readers

Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

In Situ Activation of Human Erythrocyte Prolidase: Potential for Enzyme Replacement Therapy in Prolidase Deficiency

Author Correction: Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization

Author Correction: Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate

Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers

Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization

Isolation of highly enriched primary human microglia for functional studies

Prolidase Deficiency in Cultured Human Fibroblasts: Biochemical Pathology and Iminodipeptide-Enhanced Growth

Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

Bi-directional cell-pericellular matrix interactions direct stem cell fate

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate

Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

H4K20me0 recognition by BRCA1–BARD1 directs homologous recombination to sister chromatids

Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma

Engineering transplantable jejunal mucosal grafts using patient-derived organoids from children with intestinal failure

Flunarizine, a Calcium Channel Antagonist, Is Partially Prophylactically Neuroprotective in Hypoxic-Ischemic Encephalopathy in the Fetal Sheep

Novel Cues Reinstate Cocaine-Seeking Behavior and Induce Fos Protein Expression as Effectively as Conditioned Cues

Pericytes take up and degrade α-synuclein but succumb to apoptosis under cellular stress

Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus

Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression

An anti-inflammatory role for C/EBPδ in human brain pericytes

Routine culture and study of adult human brain cells from neurosurgical specimens

Optimal scheduling to reduce morbidity of involved field radiotherapy with transplantation for lymphomas: A Prospective Australasian Leukaemia and Lymphoma Group Study

Search

Quick links

Search

Filter By:

Search

Quick links