Nature Search

Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

Polygenic risk scores for Alzheimer’s disease derived from individuals of European ancestry can show improved performance in multiancestry settings after incorporating genome-wide association summary statistics from diverse populations.

Aude Nicolas
Richard Sherva
Jean-Charles Lambert
ResearchOpen Access18 Jun 2025
Nature Genetics

P: 1-13
One or more bound planets per Milky Way star from microlensing observations

A statistical analysis of microlensing data from 2002–07 reveals that stars in the Milky Way are orbited by planets as a rule, rather than an exception.

A. Cassan
D. Kubas
Ł. Wyrzykowski
Research11 Jan 2012
Nature

Volume: 481, P: 167-169
microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

microbeMASST is a tool to associate known and unknown metabolites to microbial producers leveraging untargeted metabolomics data.

Simone Zuffa
Robin Schmid
Pieter C. Dorrestein
ResearchOpen Access05 Feb 2024
Nature Microbiology

Volume: 9, P: 336-345
The endocannabinoid system controls food intake via olfactory processes

This study shows that activation of cannabinoid type-1 (CB1) receptors in the olfactory bulb increases odor detection and food intake in hungry mice. The authors show that this function is mediated by CB1-dependent attenuation of excitatory corticofugal synaptic transmission onto inhibitory granule cells and disinhibition of mitral cells in the main olfactory bulb.

Edgar Soria-Gómez
Luigi Bellocchio
Giovanni Marsicano
Research09 Feb 2014
Nature Neuroscience

Volume: 17, P: 407-415
Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

Oligodendroglial tumours are characterized into three different molecular subtypes. Here, the authors use genomic data to identify a further three subgroups of 1p/19q co-deleted tumours and demonstrate an association with an aggressive phenotype.

Aurélie Kamoun
Ahmed Idbaih
Chiara Villa
ResearchOpen Access19 Apr 2016
Nature Communications

Volume: 7, P: 1-11
GABA_A receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl⁻-sensitive WNK1 kinase

GABAergic transmission regulates the K⁺-Cl⁻ co-transporter KCC2. Here the authors demonstrate that inhibitory transmission, via GABA_A receptor and WNK signaling, regulates KCC2 expression in the membrane of hippocampal neurons.

Martin Heubl
Jinwei Zhang
Sabine Lévi
ResearchOpen Access24 Nov 2017
Nature Communications

Volume: 8, P: 1-17
Feature-based molecular networking in the GNPS analysis environment

Feature-based molecular networking allows the generation of molecular networks for mass spectrometry data that can recognize isomers, incorporate relative quantification and integrate ion mobility data.

Louis-Félix Nothias
Daniel Petras
Pieter C. Dorrestein
Research24 Aug 2020
Nature Methods

Volume: 17, P: 905-908
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Genetic ancestry and diagnostic yield of exome sequencing in a diverse population

Yusuph Mavura
Nuriye Sahin-Hodoglugil
Neil Risch
ResearchOpen Access03 Jan 2024
npj Genomic Medicine

Volume: 9, P: 1-14
Molecular analysis integrating different pathways associated with androgen-independent progression in LuCaP 23.1 xenograft

Palma Rocchi
Xavier Muracciole
Pierre-Marie Martin
Research18 Oct 2004
Oncogene

Volume: 23, P: 9111-9119
Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

Anne Slavotinek
Shannon Rego
Mary E. Norton
ResearchOpen Access26 May 2023
npj Genomic Medicine

Volume: 8, P: 1-10
Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment

To bridge the current gap between the known mechanisms of atrial fibrillation (AF) and the clinical management of patients with this arrhythmia, Fabritz and colleagues propose a roadmap to develop a set of clinical markers that reflect the major causes of AF in patients. A new, mechanism-based classification of AF can provide the basis for personalized prevention and management.

Larissa Fabritz
Eduard Guasch
Paulus Kirchhof
ReviewsOpen Access24 Dec 2015
Nature Reviews Cardiology

Volume: 13, P: 230-237
The European LeukemiaNet AML Working Party consensus statement on allogeneic HSCT for patients with AML in remission: an integrated-risk adapted approach

Allogeneic haematopoietic stem-cell transplantation (HSCT) is frequently applied as part of treatment in patients with acute myeloid leukaemia in their first or subsequent remission. In this Review, the authors propose risk assessment as a dynamic process during treatment, incorporating both disease-related and transplant-related factors for the decision to proceed either to allogeneic HSCT or to apply a nontransplant strategy.

Jan J. Cornelissen
Alois Gratwohl
Gert J. Ossenkoppele
Reviews04 Sept 2012
Nature Reviews Clinical Oncology

Volume: 9, P: 579-590
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Author Correction: Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

Anne Slavotinek
Shannon Rego
Mary E. Norton
Amendments and CorrectionsOpen Access23 Oct 2023
npj Genomic Medicine

Volume: 8, P: 1
The impact of adult neurogenesis on affective functions: of mice and men

Mariana Alonso
Anne-Cécile Petit
Pierre-Marie Lledo
ReviewsOpen Access18 Mar 2024
Molecular Psychiatry

Volume: 29, P: 2527-2542
Comparable survival using a CMV-matched or a mismatched donor for CMV+ patients undergoing T-replete haplo-HSCT with PT-Cy for acute leukemia: a study of behalf of the infectious diseases and acute leukemia working parties of the EBMT

Simone Cesaro
Roberto Crocchiolo
Jan Styczynski
Research12 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 422-430
Compatibility at amino acid position 98 of MICB reduces the incidence of graft-versus-host disease in conjunction with the CMV status

Raphael Carapito
Ismail Aouadi
Seiamak Bahram
Research14 Apr 2020
Bone Marrow Transplantation

Volume: 55, P: 1367-1378
The EBMT–ELN working group recommendations on the prophylaxis and treatment of GvHD: a change-control analysis

T Ruutu
A Gratwohl
R F Duarte
Special Features28 Nov 2016
Bone Marrow Transplantation

Volume: 52, P: 357-362

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