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Showing 1–4 of 4 results

Advanced filters: Author: Priscilia Chopard Clear advanced filters

Geographic and age variations in mutational processes in colorectal cancer

Analysis of genomic data from 981 colorectal cancers from participants in 11 countries reveals variations in mutational signatures of microsatellite-stable cancers that are dependent on geographical origin and age at which the cancer was diagnosed.

Marcos Díaz-Gay
Wellington dos Santos
Ludmil B. Alexandrov
ResearchOpen Access23 Apr 2025
Nature

Volume: 643, P: 230-240
The complexity of tobacco smoke-induced mutagenesis in head and neck cancer

Whole-genome sequencing and mutational signature analysis of 265 head and neck cancer samples collected from eight different countries provide insight into the vital contribution of tobacco smoke in disease etiology.

Laura Torrens
Sarah Moody
Sandra Perdomo
ResearchOpen Access31 Mar 2025
Nature Genetics

Volume: 57, P: 884-896
Geographic variation of mutagenic exposures in kidney cancer genomes

Whole-genome sequencing of 962 clear cell renal cell carcinomas from 11 countries shows geographic variations in somatic mutation profiles, including a mutational signature of unknown cause in 70% of cases from Japan.

Sergey Senkin
Sarah Moody
Paul Brennan
ResearchOpen Access01 May 2024
Nature

Volume: 629, P: 910-918
Aristolochic acid exposure in Romania and implications for renal cell carcinoma

Robert J Turesky
Byeong Hwa Yun
Ghislaine Scelo
ResearchOpen Access10 Dec 2015
British Journal of Cancer

Volume: 114, P: 76-80