Nature Search

Neratinib enhances the efficacy of CDK4/6 inhibitor plus endocrine therapy in HR⁺/HER2-low breast cancer cell line ZR-75-1 via hsa-miR-23a-5p

Liushan Chen
Lingling Ye
Qianjun Chen
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-16
Spatially resolved atlas of breast cancer uncovers intercellular machinery of venular niche governing lymphocyte extravasation

This study utilizes Stereo-seq to comprehensively map the geospatial architecture of breast cancer, revealing venular niches that promote immune infiltration and better clinical outcomes, offering new insights into tumor microenvironment regulation.

Xin Wang
Zhanyu Wang
Jianming Ying
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-18
Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing

Hydrogenation is a treatment for chronic inflammation caused by high glucose levels in diabetic ulcers, However, current therapies have limitations. Here, the authors report on the creation of a visible light photocatalytic agent which depletes glucose in the wound and generates hydrogen to aid in diabetic wound healing.

Shengqiang Chen
Yanxia Zhu
Qianjun He
ResearchOpen Access27 Sept 2022
Nature Communications

Volume: 13, P: 1-11
Local H₂ release remodels senescence microenvironment for improved repair of injured bone

Senescence microenvironment inhibits tissue repair in elderly individuals. Here, the authors demonstrate that local H₂ supply has anti-inflammation and anti-senescence effects, and develop a H₂-releasing scaffold to enhance aging bone defect repair.

Shengqiang Chen
Yuanman Yu
Qianjun He
ResearchOpen Access27 Nov 2023
Nature Communications

Volume: 14, P: 1-16
Photocatalysis-mediated drug-free sustainable cancer therapy using nanocatalyst

Nanoparticles have been used to reduce the toxicity associated with chemotherapeutic agents. Here, the authors report a Z-scheme SnS_1.68-WO_2.41 nanocatalyst for photocatalytic generation of oxidative holes and hydrogen molecules for drug-free therapeutic strategy.

Bin Zhao
Yingshuai Wang
Qianjun He
ResearchOpen Access01 Mar 2021
Nature Communications

Volume: 12, P: 1-11
Water oxidation on a mononuclear manganese heterogeneous catalyst

Nature’s oxygen-evolving complex of photosystem II is a multinuclear manganese cluster. Whether mononuclear manganese can also efficiently catalyse water oxidation has been a long-standing question. Now, Li and co-workers show that single atoms of manganese can be anchored on nitrogen-doped graphene to catalyse the oxygen evolution reaction. Credit: Water image Frankie Angel / Alamy Stock Photo.

Jingqi Guan
Zhiyao Duan
Can Li
Research15 Oct 2018
Nature Catalysis

Volume: 1, P: 870-877
Local generation of hydrogen for enhanced photothermal therapy

The tracking and targeted release of multi-agents to cooperatively treat cancer is a developing and evolving field. Here, the authors demonstrate the anticancer effects of cubic Pd hydride nanocrystals with photoacoustic imaging properties that can release hydrogen under an NIR trigger and have photothermal effects.

Penghe Zhao
Zhaokui Jin
Qianjun He
ResearchOpen Access12 Oct 2018
Nature Communications

Volume: 9, P: 1-12
Long-term monitoring of intravital biological processes using fluorescent protein-assisted NIR-II imaging

The retention time and toxicity of synthetic NIR-II fluorophores limit long-term application. Here the authors use infrared fluorescent proteins (iRFPs) as NIR-II probes for prolonged continuous imaging in mice, and generate a transgenic mouse model which they use to image liver and pancreas.

Muxiong Chen
Zhe Feng
Zhengping Xu
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-11
A rare deep intronic mutation of PKHD1 gene, c.8798-459 C > A, causes autosomal recessive polycystic kidney disease by pseudoexon activation

Jing Chen
Na Ma
Juan Du
Research07 Jan 2019
Journal of Human Genetics

Volume: 64, P: 207-214
Operator Radiation and the Efficacy of Ceiling-Suspended Lead Screen Shielding during Coronary Angiography: An Anthropomorphic Phantom Study Using Real-Time Dosimeters

Qianjun Jia
Ziman Chen
Wensheng Liang
ResearchOpen Access07 Feb 2017
Scientific Reports

Volume: 7, P: 1-8
Engineered NIR-II fluorophores with ultralong-distance molecular packing for high-contrast deep lesion identification

To achieve high-contrast in fluorescence imaging of deep tissues is challenging. Here, the authors develop NIR-II fluorescent small molecules with high brightness and emission extending to 1900 nm, enabling in vivo imaging of deep tissues with enhanced signal-to-background ratios.

Zhe Feng
Yuanyuan Li
Jun Qian
ResearchOpen Access18 Aug 2023
Nature Communications

Volume: 14, P: 1-14
Construction and validation of a novel prognostic model of neutrophil‑related genes signature of lung adenocarcinoma

Qianjun Zhu
Yanfei Chai
Wei Feng
ResearchOpen Access25 Oct 2023
Scientific Reports

Volume: 13, P: 1-18
Genome-wide Target Enrichment-aided Chip Design: a 66 K SNP Chip for Cashmere Goat

Xian Qiao
Rui Su
Jinquan Li
ResearchOpen Access17 Aug 2017
Scientific Reports

Volume: 7, P: 1-13
A nanoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrug resistant breast cancer

Shengrong Guo
Li Lv
Xiaoyuan Chen
ResearchOpen Access15 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Identification of selection signals by large-scale whole-genome resequencing of cashmere goats

Xiaokai Li
Rui Su
Jinquan Li
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-10
Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions

Min Yang
Shen Song
Lin Jiang
ResearchOpen Access18 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

Pulin Che
Youfeng Yang
Qiang Ding
ResearchOpen Access13 Feb 2015
Scientific Reports

Volume: 5, P: 1-10
Polyethylene glycol modification decreases the cardiac toxicity of carbonaceous dots in mouse and zebrafish models

Jian-tao Chen
Hua-qin Sun
Hui-le Gao
Research12 Oct 2015
Acta Pharmacologica Sinica

Volume: 36, P: 1349-1355
Perfecting and extending the near-infrared imaging window

Moderate light absorption by bio-tissue is conducive to the imaging performance. The second near-infrared window is perfected as 900–1880 nm, and 2080–2340 nm is proposed as the third near-infrared window.

Zhe Feng
Tao Tang
Jun Qian
ResearchOpen Access24 Sept 2021
Light: Science & Applications

Volume: 10, P: 1-18

Search

Neratinib enhances the efficacy of CDK4/6 inhibitor plus endocrine therapy in HR⁺/HER2-low breast cancer cell line ZR-75-1 via hsa-miR-23a-5p

Spatially resolved atlas of breast cancer uncovers intercellular machinery of venular niche governing lymphocyte extravasation

Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing

Local H₂ release remodels senescence microenvironment for improved repair of injured bone

Photocatalysis-mediated drug-free sustainable cancer therapy using nanocatalyst

Water oxidation on a mononuclear manganese heterogeneous catalyst

Local generation of hydrogen for enhanced photothermal therapy

Long-term monitoring of intravital biological processes using fluorescent protein-assisted NIR-II imaging

A rare deep intronic mutation of PKHD1 gene, c.8798-459 C > A, causes autosomal recessive polycystic kidney disease by pseudoexon activation

Operator Radiation and the Efficacy of Ceiling-Suspended Lead Screen Shielding during Coronary Angiography: An Anthropomorphic Phantom Study Using Real-Time Dosimeters

Engineered NIR-II fluorophores with ultralong-distance molecular packing for high-contrast deep lesion identification

Construction and validation of a novel prognostic model of neutrophil‑related genes signature of lung adenocarcinoma

Genome-wide Target Enrichment-aided Chip Design: a 66 K SNP Chip for Cashmere Goat

A nanoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrug resistant breast cancer

Identification of selection signals by large-scale whole-genome resequencing of cashmere goats

Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase

Polyethylene glycol modification decreases the cardiac toxicity of carbonaceous dots in mouse and zebrafish models

Perfecting and extending the near-infrared imaging window

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