Nature Search

Oscillation-induced yield loss in China partially driven by migratory pests from mainland Southeast Asia

Climate oscillations, such as El Niño/Southern Oscillation (ENSO), play a key role in global and regional crop yield variations. The authors analysed crop yield data in China from 1980 to 2017 and found that ENSO affects yield not only through local climate variability but also by driving migratory crop pest outbreaks, highlighting an overlooked pathway by which ENSO drives yield loss.

Chenzhi Wang
Xuhui Wang
Shilong Piao
Research18 Apr 2025
Nature Food

P: 1-11
Retraction Note: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer

Zhenqiang Sun
Chunlin Ou
Xiayu Li
Amendments and Corrections28 Jul 2023
Oncogene

Volume: 42, P: 2657
Super-enhancer RNA m⁶A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinoma

In pancreatic duct adenocarcinoma, super-enhancer RNAs (seRNAs) have higher N⁶-methyladenosine (m⁶A) levels than in adjacent normal tissue due to upregulation of the METTL3 cofactor CFL1. Aberrant m⁶A seRNAs promote oncogene expression via the YTHDC2–MLL1 complex.

Rui Li
Hongzhe Zhao
Jian Zheng
Research13 Nov 2023
Nature Genetics

Volume: 55, P: 2224-2234
CSTF2 mediated mRNA N⁶-methyladenosine modification drives pancreatic ductal adenocarcinoma m⁶A subtypes

N6-methyladenosine (m6A) modification has important implications in different cancer subtypes. Here, the authors perform transcriptomic m6A profiling to identify two subtypes of pancreatic ductal adenocarcinoma with differential m6A modifications and different clinical outcomes, which is driven by m6A regulator CSTF2.

Yanfen Zheng
Xingyang Li
Zhixiang Zuo
ResearchOpen Access10 Oct 2023
Nature Communications

Volume: 14, P: 1-17
Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis

Osteoarthritis (OA) is associated with cartilage degeneration, and no effective therapy exists. Here, the authors show that the HPIP protein modulates OA progression by regulating Wnt signaling, and that its knockdown in joints via AAV-mediated gene silencing attentuates pathology.

Quanbo Ji
Xiaojie Xu
Yan Wang
ResearchOpen Access18 Jan 2019
Nature Communications

Volume: 10, P: 1-15
CSTF2-impeded innate αβ T cell infiltration and activation exacerbate immune evasion of pancreatic cancer

Xiaowei He
Ji Liu
Jialiang Zhang
Research19 Feb 2025
Cell Death & Differentiation

Volume: 32, P: 973-988
Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

Huilin Ye
Quanbo Zhou
Rufu Chen
ResearchOpen Access18 Apr 2018
Cell Death & Disease

Volume: 9, P: 1-19
FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma

Huilin Ye
Quanbo Zhou
Rufu Chen
ResearchOpen Access18 Jan 2018
Cell Death & Disease

Volume: 9, P: 1-19
Tumour-associated macrophages and Schwann cells promote perineural invasion via paracrine loop in pancreatic ductal adenocarcinoma

Bin Zhang
Xiaofeng Guo
Quanbo Zhou
Research22 Dec 2023
British Journal of Cancer

Volume: 130, P: 542-554
Correction: Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

Lusheng Wei
Huilin Ye
Rufu Chen
Amendments and CorrectionsOpen Access03 Mar 2021
Cell Death & Disease

Volume: 12, P: 1-2
RETRACTED ARTICLE: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer

Zhenqiang Sun
Chunlin Ou
Xiayu Li
ResearchOpen Access10 Dec 2018
Oncogene

Volume: 38, P: 2627-2644
The risk variant rs884225 within EGFR impairs miR-103a-3p’s anti-tumourigenic function in non-small cell lung cancer

Zhongyi Fan
Jing Yang
Shunchang Jiao
Research23 Nov 2018
Oncogene

Volume: 38, P: 2291-2304
LncRNA BCAN-AS1 stabilizes c-Myc via N⁶-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer

Guandi Wu
Jiachun Su
Jian Zheng
Research19 Sept 2023
Cell Death & Differentiation

Volume: 30, P: 2213-2230
Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair

Xiang Zhang
Shangyou Zheng
Quanbo Zhou
ResearchOpen Access09 Mar 2022
Oncogene

Volume: 41, P: 2372-2389
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation

Lusheng Wei
Qing Lin
Quanbo Zhou
ResearchOpen Access29 Mar 2021
Cell Death & Disease

Volume: 12, P: 1-14
Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

Lusheng Wei
Huilin Ye
Rufu Chen
ResearchOpen Access18 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-17
Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells

Zhiqiang Fu
Guolin Li
Rufu Chen
ResearchOpen Access29 May 2017
Cell Death Discovery

Volume: 3, P: 1-10
Pre-metastatic niche: formation, characteristics and therapeutic implication

Yuhang Wang
Jiachi Jia
Shuaixi Yang
ReviewsOpen Access25 Sept 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-31

Search

Oscillation-induced yield loss in China partially driven by migratory pests from mainland Southeast Asia

Retraction Note: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer

Super-enhancer RNA m⁶A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinoma

CSTF2 mediated mRNA N⁶-methyladenosine modification drives pancreatic ductal adenocarcinoma m⁶A subtypes

Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis

CSTF2-impeded innate αβ T cell infiltration and activation exacerbate immune evasion of pancreatic cancer

Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma

Tumour-associated macrophages and Schwann cells promote perineural invasion via paracrine loop in pancreatic ductal adenocarcinoma

Correction: Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

RETRACTED ARTICLE: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer

The risk variant rs884225 within EGFR impairs miR-103a-3p’s anti-tumourigenic function in non-small cell lung cancer

LncRNA BCAN-AS1 stabilizes c-Myc via N⁶-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer

Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair

Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation

Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer

Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells

Pre-metastatic niche: formation, characteristics and therapeutic implication

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