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Recognition and control of neutrophil extracellular trap formation by MICL

How MICL recognizes and autoregulates the formation of neutrophil extracellular traps is explored in mouse models and human patients where disease severity is associated with aberrant neutrophil extracellular trap formation.

Mariano Malamud
Lauren Whitehead
Gordon D. Brown
ResearchOpen Access14 Aug 2024
Nature

Volume: 633, P: 442-450
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

The C-type lectin receptor MelLec recognizes DHN-melanin in conidial spores of Aspergillus fumigatus and other DHN-melanized fungi, revealing an important role for this receptor in antifungal immunity in both mice and humans.

Mark H. T. Stappers
Alexandra E. Clark
Gordon D. Brown
Research28 Feb 2018
Nature

Volume: 555, P: 382-386

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Recognition and control of neutrophil extracellular trap formation by MICL

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

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