In postnatal life, oral mucosal immunity is shaped by microbiota and the interrelating immune cells. Here, the authors show that although microbial factors facilitate the differentiation of oral Langerhans cells, their function in surveillance of mucosal epithelial barriers and capacity to induce adaptive immunity is predominantly governed by masticatory mechanical forces.
- Yasmin Jaber
- Yasmine Netanely
- Avi-Hai Hovav
