Nature Search

Interoceanic Colonization of a Marine Goby through the Panama Canal

ROBERTA W. RUBINOFF
IRA RUBINOFF
Research01 Feb 1968
Nature

Volume: 217, P: 476-478
Discovery of mammalian collagens I and III within ancient poriferan biopolymer spongin

Scientists find that spongin, a key biomaterial in sponges, contains the same collagens as mammals and that these biocomposites contain brominated crosslinks. Now, the question: “Maybe we are all sponge to some degree?” is no longer so absurd.

Hermann Ehrlich
Ivan Miksik
Markus J. Buehler
ResearchOpen Access13 Mar 2025
Nature Communications

Volume: 16, P: 1-13
DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress

Proximity between mitochondria and endoplasmic reticulum regulates mitochondria fitness and is adversely affected by tissue ischemia. This work reveals that Diaphanous1-Mitofusin2 interaction regulates this proximity and impairs recovery in ischemia.

Gautham Yepuri
Lisa M. Ramirez
Ravichandran Ramasamy
ResearchOpen Access30 Oct 2023
Nature Communications

Volume: 14, P: 1-25
Magnetic fingerprint of individual Fe₄ molecular magnets under compression by a scanning tunnelling microscope

The incorporation of single-molecule magnets into spintronic devices is often hindered by electronic or structural modifications. Here, the authors demonstrate how confinement of Fe₄ molecules in junctions between a Cu₂N substrate and a scanning microscope tip enhances intra-molecular exchange interaction.

Jacob A.J. Burgess
Luigi Malavolti
Sebastian Loth
ResearchOpen Access11 Sept 2015
Nature Communications

Volume: 6, P: 1-7
An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

Using engineered cardiac tissues, Fleischer, Nash et al. found that patients with lupus-mediated cardiac damage have unique autoantibodies that can independently alter tissue function. They also identified autoantibodies associated with heart injury.

Sharon Fleischer
Trevor R. Nash
Gordana Vunjak-Novakovic
ResearchOpen Access15 Aug 2024
Nature Cardiovascular Research

Volume: 3, P: 1123-1139
Optimal ¹³C NMR investigation of intrinsically disordered proteins at 1.2 GHz

The recently available 28.2 Tesla nuclear magnetic resonance spectrometers (1.2 GHz ¹H frequency) can be used to characterize highly flexible proteins and protein regions. This protocol explains how to setup ¹³C nuclear magnetic resonance experiments to achieve optimal results.

Marco Schiavina
Lorenzo Bracaglia
Roberta Pierattelli
Protocols12 Dec 2023
Nature Protocols

Volume: 19, P: 406-440
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models

Silvia La Monica
Federica Vacondio
Roberta Alfieri
ResearchOpen Access18 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Melioidosis and glanders are multifaceted infections caused by gram-negative bacteria. Here, the authors synthesize a series of oligosaccharides that mimic the lipopolysaccharides present on the pathogens’ surface and use them to develop novel glycoconjugates for vaccine development.

Marielle Tamigney Kenfack
Marcelina Mazur
Charles Gauthier
ResearchOpen Access24 Jul 2017
Nature Communications

Volume: 8, P: 1-13
Enhancing all-in-one bioreactors by combining interstitial perfusion, electrical stimulation, on-line monitoring and testing within a single chamber for cardiac constructs

Roberta Visone
Giuseppe Talò
Matteo Moretti
ResearchOpen Access16 Nov 2018
Scientific Reports

Volume: 8, P: 1-13
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease

Mechanistic target of rapamycin mTOR complex 1 (mTORC1) is a central regulator of cellular metabolism. Recent studies of the molecular architecture of mTORC1 shed new light on its physiological functions and on the consequences of their dysregulation in cancer, type 2 diabetes and neurodegeneration.

Claire Goul
Roberta Peruzzo
Roberto Zoncu
Reviews23 Aug 2023
Nature Reviews Molecular Cell Biology

Volume: 24, P: 857-875
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

In several human and mouse cancer cell lines and carcinomas, a sapienate biosynthesis pathway underpins metabolic plasticity by allowing these cells to bypass stearoyl-CoA desaturase-dependent fatty acid desaturation.

Kim Vriens
Stefan Christen
Sarah-Maria Fendt
Research06 Feb 2019
Nature

Volume: 566, P: 403-406
Linking functions: an additional role for an intrinsically disordered linker ___domain in the transcriptional coactivator CBP

Sara Contreras-Martos
Alessandro Piai
Peter Tompa
ResearchOpen Access05 Jul 2017
Scientific Reports

Volume: 7, P: 1-13
Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

This Perspective highlights notable milestones from the past two decades of research in cardiac tissue engineering, and outlines opportunities and challenges for further advancement.

Richard Z. Zhuang
Roberta Lock
Gordana Vunjak-Novakovic
Reviews27 Apr 2022
Nature Biomedical Engineering

Volume: 6, P: 327-338
De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy

Rima Nabbout and colleagues report the identification of de novo mutations in the KCNT1 potassium channel gene in individuals with malignant migrating partial seizures of infancy, a rare epileptic encephalopathy with pharmacoresistant seizures and developmental delay. The authors show that the mutations have a gain-of-function effect on KCNT1 channel activity.

Giulia Barcia
Matthew R Fleming
Rima Nabbout
Research21 Oct 2012
Nature Genetics

Volume: 44, P: 1255-1259
Fluorescent analyses of sediments and near-seabed water in the area of the WW2 shipwreck “Stuttgart”

Emilia Baszanowska
Zbigniew Otremba
Maria Kubacka
ResearchOpen Access19 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase

Rosa Ester Forgione
Cristina Di Carluccio
Alba Silipo
ResearchOpen Access31 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
A fine-tuned β-catenin regulation during proliferation of corneal endothelial cells revealed using proteomics analysis

Eleonora Maurizi
Davide Schiroli
Graziella Pellegrini
ResearchOpen Access14 Aug 2020
Scientific Reports

Volume: 10, P: 1-16
Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats

Luciano Cardoso Santos
Jeane Martinha dos Anjos Cordeiro
Juneo Freitas Silva
ResearchOpen Access05 Oct 2023
Scientific Reports

Volume: 13, P: 1-16
Effects of optogenetic inhibition of a small fraction of parvalbumin-positive interneurons on the representation of sensory stimuli in mouse barrel cortex

Fahimeh Yeganeh
Beate Knauer
Maik C. Stüttgen
ResearchOpen Access12 Nov 2022
Scientific Reports

Volume: 12, P: 1-13
RAGE/SNAIL1 signaling drives epithelial-mesenchymal plasticity in metastatic triple-negative breast cancer

Mireia Pujals
Carla Mayans
Josep Villanueva
Research19 Jul 2023
Oncogene

Volume: 42, P: 2610-2628
The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata

Kenichi Kamata
Kenji Mizutani
Jeremy R. H. Tame
ResearchOpen Access16 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
A framework for developing sex-specific engineered heart models

Sex-related differences in health and disease are often overlooked in tissue engineering. This Review discusses sex-based differences in the (patho)physiology of the cardiovascular system, providing a design framework for sex-specific cardiac tissue models and an outlook to developing sex-specific in vitro models in general.

Roberta Lock
Hadel Al Asafen
Gordana Vunjak-Novakovic
Reviews20 Oct 2021
Nature Reviews Materials

Volume: 7, P: 295-313
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

Anna Montanaro
Samuel Kitara
Giovanni Roti
ResearchOpen Access17 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-14
Exploring the microbial biotransformation of extraterrestrial material on nanometer scale

Tetyana Milojevic
Denise Kölbl
Alexandra N. Rupert
ResearchOpen Access02 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Engineering a humanized bone organ model in mice to study bone metastases

This protocol describes how to design 3D-printed scaffolds via melt electrospinning writing for bone tissue engineering applications and how to engineer humanized bone for the study of cancer metastasis in vivo.

Laure C Martine
Boris M Holzapfel
Dietmar W Hutmacher
Protocols02 Mar 2017
Nature Protocols

Volume: 12, P: 639-663
Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity

Malcolm J. Daniels
J. Brucker Nourse Jr.
Harry Ischiropoulos
ResearchOpen Access27 Feb 2019
Scientific Reports

Volume: 9, P: 1-17
Poor outcome of patients with COVID-19 after CAR T-cell therapy for B-cell malignancies: results of a multicenter study on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Infectious Diseases Working Party and the European Hematology Association (EHA) Lymphoma Group

Anne Mea Spanjaart
Per Ljungman
Stephan Mielke
ResearchOpen Access08 Nov 2021
Leukemia

Volume: 35, P: 3585-3588

Search

Interoceanic Colonization of a Marine Goby through the Panama Canal

Discovery of mammalian collagens I and III within ancient poriferan biopolymer spongin

DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress

Magnetic fingerprint of individual Fe₄ molecular magnets under compression by a scanning tunnelling microscope

An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

Optimal ¹³C NMR investigation of intrinsically disordered proteins at 1.2 GHz

Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models

Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

Enhancing all-in-one bioreactors by combining interstitial perfusion, electrical stimulation, on-line monitoring and testing within a single chamber for cardiac constructs

The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Linking functions: an additional role for an intrinsically disordered linker ___domain in the transcriptional coactivator CBP

Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy

Fluorescent analyses of sediments and near-seabed water in the area of the WW2 shipwreck “Stuttgart”

Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase

A fine-tuned β-catenin regulation during proliferation of corneal endothelial cells revealed using proteomics analysis

Kisspeptin treatment reverses high prolactin levels and improves gonadal function in hypothyroid male rats

Effects of optogenetic inhibition of a small fraction of parvalbumin-positive interneurons on the representation of sensory stimuli in mouse barrel cortex

RAGE/SNAIL1 signaling drives epithelial-mesenchymal plasticity in metastatic triple-negative breast cancer

The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata

A framework for developing sex-specific engineered heart models

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

Exploring the microbial biotransformation of extraterrestrial material on nanometer scale

Engineering a humanized bone organ model in mice to study bone metastases

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity

Poor outcome of patients with COVID-19 after CAR T-cell therapy for B-cell malignancies: results of a multicenter study on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Infectious Diseases Working Party and the European Hematology Association (EHA) Lymphoma Group

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