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Nature Genetics (2)
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Showing 1–3 of 3 results

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Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

Single-nucleus and spatial, whole-transcriptome profiling of 43 pancreatic adenocarcinomas provides a refined molecular and cellular classification, highlighting a new neoadjuvant treatment-associated neural-like progenitor tumor cell state.

William L. Hwang
Karthik A. Jagadeesh
Aviv Regev
Research28 Jul 2022
Nature Genetics

Volume: 54, P: 1178-1191
Base-resolution models of transcription-factor binding reveal soft motif syntax

BPNet is an interpretable deep learning tool that predicts transcription-factor binding profiles from DNA sequence at base-pair resolution, enabling the identification of motifs and the regulatory syntax underlying transcription-factor binding.

Žiga Avsec
Melanie Weilert
Julia Zeitlinger
Research18 Feb 2021
Nature Genetics

Volume: 53, P: 354-366
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Single-cell analysis of lung, heart, kidney and liver autopsy samples shows the molecular and cellular changes and immune response resulting from severe COVID-19 infection.

Toni M. Delorey
Carly G. K. Ziegler
Aviv Regev
Research29 Apr 2021
Nature

Volume: 595, P: 107-113