Nature Search

Indigenous-led conservation improves outcomes in protected areas

Jeffrey Wall
Faisal Moola
Robin Roth
Correspondence09 May 2025
Nature Reviews Biodiversity

Volume: 1, P: 411-412
Unevidenced biodiversity claim should be abandoned — but biodiversity can be counted

Robin Naidoo
Colby Loucks
Correspondence08 Oct 2024
Nature

Volume: 634, P: 298
Wildlife’s contributions to people

Wildlife are central to nature’s contributions to people (NCP) but are often overlooked in NCP policy and management. This Perspective presents evidence for the integral role of wildlife in supporting human well-being and proposes their recognition and incorporation into conservation decision-making as wildlife’s contributions to people (WCP).

Rebecca Chaplin-Kramer
Colleen R. Miller
Jiaying Zhao
Reviews15 Jan 2025
Nature Reviews Biodiversity

Volume: 1, P: 68-81
Mammals show faster recovery from capture and tagging in human-disturbed landscapes

In wildlife tagging, stress from capture and handling can alter post- release behavior and potentially study interpretations. This study of 42 mammal species shows that these effects diminish within 4–7 days, and quicker for animals in high human activity areas indicating adaptation to disturbance.

Jonas Stiegler
Cara A. Gallagher
Niels Blaum
ResearchOpen Access15 Sept 2024
Nature Communications

Volume: 15, P: 1-13
Quantum key distribution implemented with d-level time-bin entangled photons

The use of time-bin entangled qudits is hindered by the phase instability, timing inaccuracy and low scalability of current interferometric schemes. Here, the authors show a fiber-pigtailed photonic chip for generating and processing picosecond-spaced time-bin entangled qudits and utilize the system to implement a quantum key distribution protocol.

Hao Yu
Stefania Sciara
Roberto Morandotti
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-10
Telomeric repeat from T. thermophila cross hybridizes with human telomeres

Robin C. Allshire
John R. Gosden
Nicholas D. Hastie
Research14 Apr 1988
Nature

Volume: 332, P: 656-659
Mammal responses to global changes in human activity vary by trophic group and landscape

Analysing camera-trap data of 163 mammal species before and after the onset of COVID-19 lockdowns, the authors show that responses to human activity are dependent on the degree to which the landscape is modified by humans, with carnivores being especially sensitive.

A. Cole Burton
Christopher Beirne
Roland Kays
ResearchOpen Access18 Mar 2024
Nature Ecology & Evolution

Volume: 8, P: 924-935
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

This study uses gene expression predictors for the dorsolateral prefrontal cortex and other brain regions to perform a transcriptomic imputation analysis of schizophrenia, identifying 413 genic associations across 13 brain regions and 36 significantly enriched pathways.

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Research25 Mar 2019
Nature Genetics

Volume: 51, P: 659-674
Associations of autozygosity with a broad range of human phenotypes

Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is associated with disadvantageous outcomes in 32 out of 100 traits tested.

David W Clark
Yukinori Okada
James F Wilson
ResearchOpen Access31 Oct 2019
Nature Communications

Volume: 10, P: 1-17
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

Tom Maniatis
Robin Reed
Reviews19 Feb 1987
Nature

Volume: 325, P: 673-678
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

An integrated analysis of de novo and inherited coding variants in 42,607 individuals with autism spectrum disorder identifies 60 risk genes of which five have not previously been associated with neurodevelopmental disorders.

Xueya Zhou
Pamela Feliciano
Wendy K. Chung
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1305-1319
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Cortex morphology varies with age, cognitive function, and in neurological and psychiatric diseases. Here the authors report 160 genome-wide significant associations with thickness, surface area and volume of the total cortex and 34 cortical regions from a GWAS meta-analysis in 22,824 adults.

Edith Hofer
Gennady V. Roshchupkin
Sudha Seshadri
ResearchOpen Access22 Sept 2020
Nature Communications

Volume: 11, P: 1-16
What do dysfunctional serpins tell us about molecular mobility and disease?

Penelope E. Stein
Robin W. Carrell
Research01 Feb 1995
Nature Structural Biology

Volume: 2, P: 96-113
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

A transancestral exome-wide association study for body-fat distribution identifies protein-coding variants that are significantly associated with waist-to-hip ratio adjusted for body mass index.

Anne E. Justice
Tugce Karaderi
Cecilia M. Lindgren
Research18 Feb 2019
Nature Genetics

Volume: 51, P: 452-469
Processing of social closeness in the human brain

Most of our social effort is dedicated to a small group of very close individuals. This study reveals that neurocognitive processing of these people differs from the broader social network, paralleling the processing of close versus distant places.

Moshe Roseman-Shalem
Robin I. M. Dunbar
Shahar Arzy
ResearchOpen Access10 Oct 2024
Communications Biology

Volume: 7, P: 1-11
Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma

Protein kinase A (PKA) is typically activated by cAMP. Here, Bachmaier et al. show that PKA of Trypanosoma is activated by nucleoside-related ligands, explain the ligand selectivity swap by a co-crystal structure of trypanosome PKAR, and identify potential downstream targets by phosphoproteomics.

Sabine Bachmaier
Yuri Volpato Santos
Michael Boshart
ResearchOpen Access29 Mar 2019
Nature Communications

Volume: 10, P: 1-14
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs

Sequencing the nuclear genomes of Guillardia theta and Bigelowiella natans, transitional forms in the endosymbiotic acquisition of photosynthesis by engulfment of certain eukaryotic algae, reveals unprecedented alternative splicing for a single-celled organism (B. natans) and extensive genetic and biochemical mosaicism, shedding light on why nucleomorphs persist in these species but not other algae.

Bruce A. Curtis
Goro Tanifuji
John M. Archibald
ResearchOpen Access28 Nov 2012
Nature

Volume: 492, P: 59-65
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
ADAM8 as a drug target in pancreatic cancer

Expression of ADAM8, a metalloprotease disintegrin, correlates with worse prognosis in pancreatic adenocarcinoma (PDAC). Here Schlomann et al. show that ADAM8 promotes PDAC invasiveness, and develop a peptide inhibitor that blocks ADAM8 function and impedes PDAC progression in mouse models.

Uwe Schlomann
Garrit Koller
Jörg W. Bartsch
Research28 Jan 2015
Nature Communications

Volume: 6, P: 1-16
Clinical trials and tribulations: lessons from spinal cord injury studies registered on ClinicalTrials.gov

Freda M. Warner
Nicole G. Bailey
John L. K. Kramer
Research03 Sept 2021
Spinal Cord

Volume: 59, P: 1256-1260
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Single-cell analysis of lung, heart, kidney and liver autopsy samples shows the molecular and cellular changes and immune response resulting from severe COVID-19 infection.

Toni M. Delorey
Carly G. K. Ziegler
Aviv Regev
Research29 Apr 2021
Nature

Volume: 595, P: 107-113
Gene expression elucidates functional impact of polygenic risk for schizophrenia

The CommonMind Consortium sequenced RNA from dorsolateral prefrontal cortex of subjects with schizophrenia (N = 258) and control subjects (N = 279), creating a resource of gene expression and its genetic regulation. Using this resource, they found that ∼20% of schizophrenia loci have variants that may contribute to altered gene expression and liability.

Menachem Fromer
Panos Roussos
Pamela Sklar
Research26 Sept 2016
Nature Neuroscience

Volume: 19, P: 1442-1453
The genome of the model beetle and pest Tribolium castaneum

The beetle Tribolium castaneum is a commonly used laboratory model, combining the ease of systematic RNAi experiments like those in Caenorhabditis elegans, with biology that is more representative of most insects than Drosophila melanogaster. A large consortium has sequenced and analysed the genome of the red flour beetle, creating a resource for biologists everywhere.

Stephen Richards
Richard A. Gibbs
Gregor Bucher
ResearchOpen Access23 Mar 2008
Nature

Volume: 452, P: 949-955
Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

Breen et al. map RNA editing profiles in cortical samples from individuals with schizophrenia and controls, and find links between altered RNA editing in glutamatergic and postsynaptic density genes and schizophrenia genetic risk architecture.

Michael S. Breen
Amanda Dobbyn
Elizabeth Zharovsky
Research27 Aug 2019
Nature Neuroscience

Volume: 22, P: 1402-1412
A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

Ten years after the discovery of the Higgs boson, the ATLAS experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 52-59
Functional annotation of rare structural variation in the human brain

Structural variants (SVs) contribute to the genetic architecture of many brain-related disorders. Here, the authors integrate SV calls from genome sequencing (n = 755) with RNA-seq data (n = 629) from post-mortem dorsal lateral prefrontal cortex to annotate the gene regulatory effects of SVs in the human brain and their potential to contribute to disease.

Lide Han
Xuefang Zhao
Douglas M. Ruderfer
ResearchOpen Access12 Jun 2020
Nature Communications

Volume: 11, P: 1-13
ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion

ASLPrep is a software suite for reproducible processing of arterial spin labeled magnetic resonance imaging data.

Azeez Adebimpe
Maxwell Bertolero
Theodore D. Satterthwaite
Research10 Jun 2022
Nature Methods

Volume: 19, P: 683-686
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Amendments and Corrections13 May 2019
Nature Genetics

Volume: 51, P: 1068
Spatially resolved emulated annual temperature projections for overshoot pathways

Jonas Schwaab
Mathias Hauser
Sonia I. Seneviratne
ResearchOpen Access21 Nov 2024
Scientific Data

Volume: 11, P: 1-10
Molecular mechanisms of cell cryopreservation with polyampholytes studied by solid-state NMR

Cellular cryopreservation is an important tool in modern biology. Here, previously reported polyampholyte cryoprotectants are studied by solid-state NMR, revealing the molecular mechanisms at play.

Kazuaki Matsumura
Fumiaki Hayashi
Suong-Hyu Hyon
ResearchOpen Access09 Feb 2021
Communications Materials

Volume: 2, P: 1-12
Dysregulation of threat neurocircuitry during fear extinction: the role of anhedonia

Katherine S. Young
Susan Y. Bookheimer
Michelle G. Craske
ResearchOpen Access08 Apr 2021
Neuropsychopharmacology

Volume: 46, P: 1650-1657
Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis

Lizzy Peix
Iona C. Evans
Robin J. McAnulty
ResearchOpen Access30 Jan 2018
Scientific Reports

Volume: 8, P: 1-15
Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder

Thomas A. Lanz
Veronica Reinhart
Robin J. Kleiman
ResearchOpen Access23 May 2019
Translational Psychiatry

Volume: 9, P: 1-13
Is body fat percentage a better measure of undernutrition in newborns than birth weight percentiles?

Angela E. Carberry
Camille H. Raynes-Greenow
Heather E. Jeffery
Research03 Sept 2013
Pediatric Research

Volume: 74, P: 730-736
Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus)

Niora J. Fabian
Anthony J. Mannion
Jennifer L. Haupt
ResearchOpen Access22 Jul 2023
Scientific Reports

Volume: 13, P: 1-15
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders

Nirmala Akula
Stefano Marenco
Francis J. McMahon
ResearchOpen Access08 Feb 2021
Neuropsychopharmacology

Volume: 46, P: 1364-1372
Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

John A. F. Zupancic
Gui-shuang Ying
Gui-shuang Ying
Research28 Feb 2020
Journal of Perinatology

Volume: 40, P: 1100-1108
Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates

Marcelo D. T. Torres et al. turn toxic wasp-derived antimicrobial peptide polybia-CP into a viable antimicrobial with therapeutic activity in a mouse model. This study demonstrates that a physicochemical property-guided rational design strategy can be used to generate peptide antibiotics.

Marcelo D. T. Torres
Cibele N. Pedron
Cesar de la Fuente-Nunez
ResearchOpen Access07 Dec 2018
Communications Biology

Volume: 1, P: 1-16
Quantitative Phase Imaging Using Digital Holographic Microscopy Reliably Assesses Morphology and Reflects Elastic Properties of Fibrotic Intestinal Tissue

Arne Bokemeyer
Phil Robin Tepasse
Dominik Bettenworth
ResearchOpen Access18 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Long-Term Reduction of Cocaine Self-Administration in Rats Treated with Adenoviral Vector-Delivered Cocaine Hydrolase: Evidence for Enzymatic Activity

Natalie E Zlebnik
Stephen Brimijoin
Marilyn E Carroll
Research10 Jan 2014
Neuropsychopharmacology

Volume: 39, P: 1538-1546
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder

Gabriel E. Hoffman
Jaroslav Bendl
Panos Roussos
ResearchOpen Access24 Sept 2019
Scientific Data

Volume: 6, P: 1-14
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Solveig K. Sieberts
Thanneer M. Perumal
Lara M. Mangravite
ResearchOpen Access12 Oct 2020
Scientific Data

Volume: 7, P: 1-11

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