Nature Search

Northward propagation of Hadley Cell in the South Asian monsoon region driven by active convection over the Qinghai–Tibet Plateau triggered by sea surface temperature warming of the North Atlantic

Wenyue Cai
Xiangde Xu
Ruibo Wang
ResearchOpen Access17 Jun 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-10
Large-scale biosynthetic analysis of human microbiomes reveals diverse protective ribosomal peptides

Here, by analyzing 306481 microbial genomes from human-associated microbiomes, the authors reveal a largely unexplored biosynthetic landscape of ribosomal peptides (RiPPs), identifying protective peptides that obstruct pathogen biofilms and regulate gut microbiota in disease models, underscoring their significant therapeutic potential.

Jian Zhang
Dengwei Zhang
Yong-Xin Li
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Visualizing the atomic-scale electronic structure of the Ca₂CuO₂Cl₂ Mott insulator

Understanding high temperature superconductivity in the cuprates is one of the hardest problems in physics to date. Wang et al.use state-of-the-art scanning tunnelling spectroscopy to visualize the atomic-scale electronic structure of the Mott insulator phase from which this elusive state emerges.

Cun Ye
Peng Cai
Yayu Wang
Research22 Jan 2013
Nature Communications

Volume: 4, P: 1-7
Author Correction: Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Wenhui Li
Xianyue Jiang
Qi Liu
Amendments and CorrectionsOpen Access09 Jan 2025
Nature Communications

Volume: 16, P: 1
Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Identification of CRISPR-Cas systems by sequence alignment is limited by homolog sequence diversity. Here, the authors develop CHOOSER, and AI framework, for alignment free discovery of CRISPR-Cas systems, including EphcCasλ, which was validated for self-processing and DNA cleavage.

Wenhui Li
Xianyue Jiang
Qi Liu
ResearchOpen Access19 Nov 2024
Nature Communications

Volume: 15, P: 1-14
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

Several engineered Cas13 variants achieve targeted RNA degradation with minimal collateral effects.

Huawei Tong
Jia Huang
Hui Yang
Research11 Aug 2022
Nature Biotechnology

Volume: 41, P: 108-119
Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

Circulating tumour DNA is used as a biomarker for cancer diagnosis. Here, the authors identified a DNA methylation biomarker for hepatocellular carcinoma and developed diagnostic and prognostic models to predict specificity and survival of patients.

Rui-hua Xu
Wei Wei
Kang Zhang
Research09 Oct 2017
Nature Materials

Volume: 16, P: 1155-1161
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations

Wang et al. developed a transformer base editor system in which the enzyme activity of the base editor is turned on only at the on-target site, therefore minimizing genome-wide and transcriptome-wide off-target mutations.

Lijie Wang
Wei Xue
Jia Chen
Research10 May 2021
Nature Cell Biology

Volume: 23, P: 552-563
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

A natural language processing system can support physicians in diagnostic assessments by extracting clinical information from electronic medical records to accurately predict diagnosis in pediatric patients.

Huiying Liang
Brian Y. Tsui
Huimin Xia
Research11 Feb 2019
Nature Medicine

Volume: 25, P: 433-438
FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis

A naturally occurring stand-alone and intermolecular Diels–Alderase, MaDA, has been identified from Morus alba cell cultures. MaDA is a FAD-dependent enzyme, which catalyses the intermolecular [4+2] cycloaddition via a concerted but asynchronous pericyclic pathway between morachalcone A and a diene generated from moracin C. Characterization revealed that MaDA possesses good substrate promiscuity towards both dienes and dienophiles.

Lei Gao
Cong Su
Xiaoguang Lei
Research25 May 2020
Nature Chemistry

Volume: 12, P: 620-628
Mechanism underlying the correlation between the warming-wetting of the Qinghai-Tibet Plateau and atmospheric energy changes in high-impact oceanic areas

Na Dong
Xiangde Xu
Runze Zhao
ResearchOpen Access26 Dec 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-11
Noise spectrum characteristics of marine pump units induced by different excitation sources

Houlin Liu
Runze Zhou
Xiaolin Wang
ResearchOpen Access23 May 2022
Scientific Reports

Volume: 12, P: 1-17
Cross-talk between freezing response and signaling for regulatory transcriptions of MIR475b and its targets by miR475b promoter in Populus suaveolens

Jun Niu
Jia Wang
Shanzhi Lin
ResearchOpen Access08 Feb 2016
Scientific Reports

Volume: 6, P: 1-11

Search

Northward propagation of Hadley Cell in the South Asian monsoon region driven by active convection over the Qinghai–Tibet Plateau triggered by sea surface temperature warming of the North Atlantic

Large-scale biosynthetic analysis of human microbiomes reveals diverse protective ribosomal peptides

Visualizing the atomic-scale electronic structure of the Ca₂CuO₂Cl₂ Mott insulator

Author Correction: Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects

Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations

Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis

Mechanism underlying the correlation between the warming-wetting of the Qinghai-Tibet Plateau and atmospheric energy changes in high-impact oceanic areas

Noise spectrum characteristics of marine pump units induced by different excitation sources

Cross-talk between freezing response and signaling for regulatory transcriptions of MIR475b and its targets by miR475b promoter in Populus suaveolens

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