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Showing 1–4 of 4 results
Advanced filters: Author: Sanchita Kashyap Clear advanced filters

  • A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.

    • Tae Hyung Won
    • Mohammad Arifuzzaman
    • Frank C. Schroeder
    Research
    Nature
    Volume: 638, P: 216-224

  • Dietary inulin fibre alters the composition and metabolism of gut microbiota, resulting in elevated levels of bile acids that subsequently trigger mucosal type 2 inflammation characterized by eosinophilia, with clinical implications for allergy and anti-helminth defence.

    • Mohammad Arifuzzaman
    • Tae Hyung Won
    • David Artis
    Research
    Nature
    Volume: 611, P: 578-584

  • A subset of group 3 innate lymphoid cells (ILC3s) expresses the transcription factor ZBTB46—which was previously thought to be restricted to conventional dendritic cells—and these ILC3s have a role in regulating intestinal health.

    • Wenqing Zhou
    • Lei Zhou
    • Gregory F. Sonnenberg
    Research
    Nature
    Volume: 609, P: 159-165