The study of the biomolecular mechanism of action of the isomers trans and cis-[PtI2(ipa)2] (I5 and I6) shows metabolic disruption, ROS generation and senescence. Functionally, I5 reduces tumor growth in vivo without systemic toxicity.
- Jorge Melones-Herrero
- Sonia Alcalá
- Isabel Sánchez-Pérez
