Nature Search

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study

Lim and colleagues present the UK PROSECO study where they assess humoral and cellular immune responses to one, two and three doses of vaccination against SARS-CoV-2 in patients with B-cell malignancies in a prospective observational study.

Sean H. Lim
Beth Stuart
David Goldblatt
ResearchOpen Access24 Mar 2022
Nature Cancer

Volume: 3, P: 552-564
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

Variation in antibody levels elicited by the COVID-19 vaccine ChAdOx1 nCov-19 is linked to specific major histocompatibility complex class II alleles, providing insight into the breadth of immune response among vaccinated individuals.

Alexander J. Mentzer
Daniel O’Connor
Julian C. Knight
ResearchOpen Access13 Oct 2022
Nature Medicine

Volume: 29, P: 147-157
Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

Carly M. Bliss
Georgina Bowyer
Katie J. Ewer
ResearchOpen Access21 Feb 2018
Scientific Reports

Volume: 8, P: 1-17
Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018

David W. Cleary
Jessica Jones
Stuart C. Clarke
ResearchOpen Access03 Aug 2022
Scientific Reports

Volume: 12, P: 1-11
Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

Tommy Rampling
Katie J. Ewer
Adrian V. S Hill
ResearchOpen Access09 Oct 2018
npj Vaccines

Volume: 3, P: 1-9
Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies

Federico Martinón-Torres
Eileen Png
Vanessa Sancho-Shimizu
ResearchOpen Access02 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic

Corine Driessens
Lynne Mills
Hans de Graaf
ResearchOpen Access22 Nov 2022
Pediatric Research

Volume: 94, P: 222-230
Paediatric research in the times of COVID-19

Paul F. Fleming
Chris Gale
Charles C. Roehr
ReviewsOpen Access20 Apr 2021
Pediatric Research

Volume: 90, P: 267-271
Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves

Olivia V. Swann
Louisa Pollock
Malcolm G. Semple
ResearchOpen Access22 Apr 2022
Pediatric Research

Volume: 93, P: 207-216

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Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Immune responses against SARS-CoV-2 variants after two and three doses of vaccine in B-cell malignancies: UK PROSECO study

Genomic investigations of unexplained acute hepatitis in children

Adeno-associated virus 2 infection in children with non-A–E hepatitis

Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP

Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018

Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP

Natural resistance to Meningococcal Disease related to CFH loci: Meta-analysis of genome-wide association studies

Parental concern for clinically vulnerable child during first 18 months of the COVID pandemic

Paediatric research in the times of COVID-19

Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves

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