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Advanced filters: Author: Semo Jun Clear advanced filters

mRNA 3′-UTR shortening is a molecular signature of mTORC1 activation

mTOR signalling regulates protein synthesis in response to changes in nutrient availability. Chang et al.demonstrate that mTOR can stimulate translation by promoting the shortening of mRNA 3′-untranslated regions, and that expression of ubiquitin ligases is selectively enhanced by this mechanism.

Jae-Woong Chang
Wei Zhang
Jeongsik Yong
Research15 Jun 2015
Nature Communications

Volume: 6, P: 1-9
Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome

Jiao Sun
Jin-Young Kim
Jeongsik Yong
ResearchOpen Access01 Oct 2024
Experimental & Molecular Medicine

Volume: 56, P: 2145-2161

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mRNA 3′-UTR shortening is a molecular signature of mTORC1 activation

Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome

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