The tumour suppressor p53 induces either apoptosis or cell-cycle arrest upon genotoxic stress. A regulatory network based on a complex of p53, the signalling protein axin, the p53 kinase HIPK2, the DNA repair-associated acetyltransferase Tip60 and Pirh2 governs the cellular response to p53 activation.
- Qinxi Li
- Shuyong Lin
- Sheng-Cai Lin
