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Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Connie R Bezzina
Julien Barc
Richard Redon
Amendments and Corrections29 Oct 2013
Nature Genetics

Volume: 45, P: 1409
Human genetic structure in Northwest France provides new insights into West European historical demography

Here, the authors look at present day and medieval genome samples from Northern France to piece together demographic history and population structure across Brittany and the Loire basin.

Isabel Alves
Joanna Giemza
Christian Dina
ResearchOpen Access07 Aug 2024
Nature Communications

Volume: 15, P: 1-18
Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Julien Barc
Rafik Tadros
Connie R. Bezzina
Amendments and Corrections26 Apr 2022
Nature Genetics

Volume: 54, P: 735
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Genome-wide association analyses identify new susceptibility loci for Brugada syndrome. Functional studies implicate microtubule-related trafficking effects on sodium channel expression as an underlying molecular mechanism.

Julien Barc
Rafik Tadros
Connie R. Bezzina
Research24 Feb 2022
Nature Genetics

Volume: 54, P: 232-239
Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Christian Dina, Nabila Bouatia-Naji, Xavier Jeunemaitre and colleagues from the Leducq Transatlantic MITRAL Network report the results of a genome-wide association study of nonsyndromic mitral valve prolapse. They identify six susceptibility loci and provide functional evidence implicating LMCD1 and TNS1 as genes influencing mitral valve development.

Christian Dina
Nabila Bouatia-Naji
Xavier Jeunemaitre
Research24 Aug 2015
Nature Genetics

Volume: 47, P: 1206-1211
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Connie Bezzina, Richard Redon and colleagues show that common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disorder with high risk of sudden cardiac death. The newly discovered loci have a large cumulative effect on disease risk and illustrate how common variants can have a strong impact on predisposition to rare diseases.

Connie R Bezzina
Julien Barc
Richard Redon
Research21 Jul 2013
Nature Genetics

Volume: 45, P: 1044-1049
Fine-scale human genetic structure in Western France

Matilde Karakachoff
Nicolas Duforet-Frebourg
Christian Dina
Research03 Sept 2014
European Journal of Human Genetics

Volume: 23, P: 831-836

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Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Human genetic structure in Northwest France provides new insights into West European historical demography

Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Genetic association analyses highlight biological pathways underlying mitral valve prolapse

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Fine-scale human genetic structure in Western France

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