Nature Search

Chemotherapy effects on brain glucose metabolism at rest

Bruno Baudino
Federico D’Agata
Gianni Bisi
ResearchOpen Access11 Feb 2011
Nature Precedings

P: 1
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters

Nucleosome organisation plays important roles in regulating functional genomic elements. Here, the authors use high-resolution profiling to analyse dynamic nucleosome positioning at inducible and cell-type-specific promoters, providing a global view of chromatin architecture at inducible promoters.

Agata Oruba
Simona Saccani
Dominic van Essen
ResearchOpen Access26 Feb 2020
Nature Communications

Volume: 11, P: 1-18
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Oestrogen negative breast cancer is associated with a poor prognosis. In this study, the authors perform a meta-analysis of 11 breast cancer genome-wide association studies and identify four new loci associated with oestrogen negative breast cancer risk. These findings may aid in stratifying patients in the clinic.

Fergus J. Couch
Karoline B. Kuchenbaecker
Antonis C. Antoniou
ResearchOpen Access27 Apr 2016
Nature Communications

Volume: 7, P: 1-13
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes

A new analysis of patients newly diagnosed with diabetes uses a data dimenionality reduction approach to understand how phenotypic variation drives diseaese onset, clinical outcomes and responses to glycemic-lowering medications.

Anand Thakarakkattil Narayanan Nair
Agata Wesolowska-Andersen
Ewan R. Pearson
Research09 May 2022
Nature Medicine

Volume: 28, P: 982-988
Durum wheat genome highlights past domestication signatures and future improvement targets

Genome assembly of durum wheat cultivar Svevo enables genome-wide genetic diversity analyses highlighting modifications imposed by thousands of years of empirical selection and breeding.

Marco Maccaferri
Neil S. Harris
Luigi Cattivelli
ResearchOpen Access08 Apr 2019
Nature Genetics

Volume: 51, P: 885-895
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Alison Dunning, Stacey Edwards and colleagues analyze 3,872 common variants across the ESR1 locus in 118,816 women. They find five independent variants within regulatory regions that associate with different breast cancer–related phenotypes and regulate the expression of ESR1, RMND1 and CCDC170.

Alison M Dunning
Kyriaki Michailidou
Stacey L Edwards
Research29 Feb 2016
Nature Genetics

Volume: 48, P: 374-386
Segregation analysis of the BRCA2 c.9227G>T variant in multiple families suggests a pathogenic role in breast and ovarian cancer predisposition

Simona Agata
Silvia Tognazzo
Marco Montagna
ResearchOpen Access19 Aug 2020
Scientific Reports

Volume: 10, P: 1-6
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Roger Milne and colleagues conduct a genome-wide association study for estrogen receptor (ER)-negative breast cancer combined with BRCA1 mutation carriers in a large cohort. They identify ten new risk variants and find high genetic correlation between breast cancer risk for BRCA1 mutation carriers and risk of ER-negative breast cancer in the general population.

Roger L Milne
Karoline B Kuchenbaecker
Jacques Simard
Research23 Oct 2017
Nature Genetics

Volume: 49, P: 1767-1778
Heterochromatin boundaries are hotspots for de novo kinetochore formation

In most eukaryotes, the centromere is defined by epigenetic marks such as the histone H3 variant CENH3/CENP-A/CID. Ectopic induction of kinetochores in Drosophila S2 cells by CID overexpression leads to kinetochore assembly specifically in silent intergenic regions bordering heterochomratin, demonstrating a role for these domains in centromere identity.

Agata M. Olszak
Dominic van Essen
Patrick Heun
Research19 Jun 2011
Nature Cell Biology

Volume: 13, P: 799-808
Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Eileen O. Dareng
Jonathan P. Tyrer
Paul D. P. Pharoah
ResearchOpen Access14 Jan 2022
European Journal of Human Genetics

Volume: 30, P: 349-362
Ecological relevance of skeletal fatty acid concentration and composition in Mediterranean scleractinian corals

Chiara Samorì
Erik Caroselli
Giuseppe Falini
ResearchOpen Access16 May 2017
Scientific Reports

Volume: 7, P: 1-8
The unique second wave phenomenon in contrast enhanced ultrasound imaging with nanobubbles

Chuan Chen
Reshani Perera
Simona Turco
ResearchOpen Access10 Aug 2022
Scientific Reports

Volume: 12, P: 1-12
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard
Michael Lush
Antonis C. Antoniou
Amendments and CorrectionsOpen Access14 May 2021
Nature Communications

Volume: 12, P: 1-2
DNA copy number alterations correlate with survival of esophageal adenocarcinoma patients

Giulia Pasello
Simona Agata
Daniela Saggioro
Research26 Sept 2008
Modern Pathology

Volume: 22, P: 58-65
Modern Iron Ooids of Hydrothermal Origin as a Proxy for Ancient Deposits

Marcella Di Bella
Giuseppe Sabatino
Francesco Italiano
ResearchOpen Access08 May 2019
Scientific Reports

Volume: 9, P: 1-9
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14
Audience spontaneous entrainment during the collective enjoyment of live performances: physiological and behavioral measurements

Martina Ardizzi
Marta Calbi
Vittorio Gallese
ResearchOpen Access02 Mar 2020
Scientific Reports

Volume: 10, P: 1-12
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Eileen O. Dareng
Jonathan P. Tyrer
Paul D. P. Pharoah
Amendments and CorrectionsOpen Access22 Mar 2022
European Journal of Human Genetics

Volume: 30, P: 630-631

Search

Chemotherapy effects on brain glucose metabolism at rest

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes

Durum wheat genome highlights past domestication signatures and future improvement targets

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Segregation analysis of the BRCA2 c.9227G>T variant in multiple families suggests a pathogenic role in breast and ovarian cancer predisposition

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Heterochromatin boundaries are hotspots for de novo kinetochore formation

Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Ecological relevance of skeletal fatty acid concentration and composition in Mediterranean scleractinian corals

The unique second wave phenomenon in contrast enhanced ultrasound imaging with nanobubbles

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

DNA copy number alterations correlate with survival of esophageal adenocarcinoma patients

Modern Iron Ooids of Hydrothermal Origin as a Proxy for Ancient Deposits

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Audience spontaneous entrainment during the collective enjoyment of live performances: physiological and behavioral measurements

Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk

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