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Showing 1–3 of 3 results
Advanced filters: Author: Simona Angerani Clear advanced filters

  • Monitoring the activity of the processive motor protein kinesin-1 in live cells is currently difficult. Here the authors report the fluorogenic small molecule QPD-OTf, a kinesin-1 substrate that causes activity-dependent dye precipitation.

    • Simona Angerani
    • Eric Lindberg
    • Nicolas Winssinger
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • Bioluminescence resonance energy transfer (BRET) has been mostly employed in imaging applications. Here the authors use BRET to activate a ruthenium-based photocatalyst and perform a bioorthogonal chemical reaction, which can be used to uncage small molecule drugs in a cellular context.

    • Eric Lindberg
    • Simona Angerani
    • Nicolas Winssinger
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9