Nature Search

AI-based large-scale screening of gastric cancer from noncontrast CT imaging

Artificial intelligence-based detection of gastric cancer at different stages from noncontrast computed tomography is suggested to be feasible in a retrospective analysis of large and diverse cohorts, including real-world populations in opportunistic and targeted screening scenarios.

Can Hu
Yingda Xia
Xiangdong Cheng
ResearchOpen Access24 Jun 2025
Nature Medicine

P: 1-9
A Mendelian randomized study of circulating antioxidants in the diet and risk of cardiovascular disease

Ruonan Yang
Mingyue Lv
Siwei Zhai
ResearchOpen Access25 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRs

Isolation of antigen-reactive T cell receptors (TCRs) to cancer epitopes is important for engineered T cell immunotherapies. Here the authors show an aptamer-based microfluidic single-cell method to isolate antigen-reactive TCRs and show proof of principle isolations for cytomegalovirus and prostate specific antigen.

Siwei Luo
Amber Notaro
Lan Lin
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-17
Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging

Sun, Fu, Zheng, Hong, Liu et al. generate a single-nucleus transcriptomic atlas of the primate cochlear aging, identifying an age-related decline in Slc35f1 and showing that silencing Slc35f1 in mice induces hair cell degeneration and auditory deficits.

Guoqiang Sun
Xiaolong Fu
Guang-Hui Liu
Research20 Jun 2025
Nature Aging

P: 1-18
Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

Invasive early stage lung adenocarcinoma has a heterogeneous prognosis. Here, the authors microdissect malignant pulmonary nodules to invasive and preinvasive components and study the mutations that are common or private between the lesions, allowing them to understand the evolutionary path of the tumours.

Siwei Wang
Mulong Du
Rong Yin
ResearchOpen Access27 Nov 2020
Nature Communications

Volume: 11, P: 1-8
Bandgap engineering of two-dimensional C₃N bilayers

The bandgaps of bilayers of two-dimensional C₃N can be modulated by controlling the stacking order of the layers or by applying an electric field.

Wenya Wei
Siwei Yang
Qinghong Yuan
Research28 Jun 2021
Nature Electronics

Volume: 4, P: 486-494
Comprehensive analysis of senescence-related genes identifies prognostic clusters with distinct characteristics in glioma

Wenyuan Wei
Ying Dang
Jungang Xue
ResearchOpen Access19 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
O-GlcNAcylation of glutaminase isoform KGA inhibits ferroptosis through activation of glutaminolysis in hepatoblastoma

Sijia Fang
Guoqing Zhu
Ji Ma
ResearchOpen Access09 Apr 2025
Cell Death Discovery

Volume: 11, P: 1-13
Inferring compound heterozygosity from large-scale exome sequencing data

A strategy for inferring phase for rare variant pairs is applied to exome sequencing data for 125,748 individuals from the Genome Aggregation Database (gnomAD). This resource will aid interpretation of rare co-occurring variants in the context of recessive disease.

Michael H. Guo
Laurent C. Francioli
Kaitlin E. Samocha
Research06 Dec 2023
Nature Genetics

Volume: 56, P: 152-161
Surface treatment of red painted and slipped wares in the middle Yangtze River valley of Late Neolithic China: multi-analytical case analysis

Tao Li
Guoyuan Li
Lihua Wang
ResearchOpen Access21 Nov 2022
Heritage Science

Volume: 10, P: 1-22
Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy

Oncolytic adenoviruses (Ads)-mediated anti-tumor activity is related to virus-promoted autophagy in tumor cells. Here the authors describe the design of a microbial nanocomposite based on Ads-encapsulated in bacterial outer membrane vesicles to promote Ads intratumoral accumulation and induction of autophagy, promoting anti-tumor immune responses in preclinical cancer models.

Weiyue Ban
Mengchi Sun
Jin Sun
ResearchOpen Access22 May 2023
Nature Communications

Volume: 14, P: 1-14
Human activities and species biological traits drive the long-term persistence of old trees in human-dominated landscapes

Old trees have many ecological and socio-cultural values that affect their survival. Species with greater potential height, smaller leaf size and diverse human utilization attributes had the highest probability of long-term persistence.

Li Huang
Cheng Jin
David B. Lindenmayer
Research11 May 2023
Nature Plants

Volume: 9, P: 898-907
Will land transfer improve grain farmers’ adoption of agricultural green production technology? Evidence from Jiangxi Province, China

Yuanyuan Peng
Jinyong Guo
Yonghong Tang
ResearchOpen Access02 Apr 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-13
Changes and continuity in pottery production and use at Wujiafentou in the core zone of Youziling and Shijiahe cultures in central China

Zichen Xie
Ying Hu
Tao Li
ResearchOpen Access20 Feb 2024
Heritage Science

Volume: 12, P: 1-31
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

Mengqi Li
Yu Wang
Sheng-Cai Lin
ResearchOpen Access19 Jun 2024
Cell Research

Volume: 34, P: 683-706
Total morphosynthesis of biomimetic prismatic-type CaCO₃ thin films

The exterior layers of mollusk shells are prismatic in nature, endowing them with stiffness and wear resistance. Inspired by these biominerals, here, Jiang and colleagues grow structurally similar prismatic-type CaCO₃ thin films with comparable stiffness and hardness.

Chuanlian Xiao
Ming Li
Helmut Cölfen
ResearchOpen Access09 Nov 2017
Nature Communications

Volume: 8, P: 1-9
Identify and validate circadian regulators as potential prognostic markers and immune infiltrates in head and neck squamous cell carcinoma

Yi Jin
Zhanwang Wang
Hui Wang
ResearchOpen Access15 Nov 2023
Scientific Reports

Volume: 13, P: 1-13
Identification and characterisation of lamprey protein kinase C delta-like gene

Yang Xu
Siwei Zhu
Qingwei Li
ResearchOpen Access22 Sept 2017
Scientific Reports

Volume: 7, P: 1-14
SNORA14A inhibits hepatoblastoma cell proliferation by regulating SDHB-mediated succinate metabolism

Jiabei Zhu
Siwei Mao
Qiuhui Pan
ResearchOpen Access30 Jan 2023
Cell Death Discovery

Volume: 9, P: 1-14
Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis

Siwei Tan
Xianzhi Liu
Bin Wu
ResearchOpen Access12 May 2021
Cell Death & Disease

Volume: 12, P: 1-18
Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

Lei Zhang
Jiabing Chen
Yong Gao
ResearchOpen Access24 Jan 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-16
Mitotic slippage is determined by p31^comet and the weakening of the spindle-assembly checkpoint

Tsun Ming Lok
Yang Wang
Randy Y. C. Poon
ResearchOpen Access06 Feb 2020
Oncogene

Volume: 39, P: 2819-2834
Dried blood sample analysis by antibody array across the total testing process

Kelly Whittaker
Ying-Qing Mao
Ruo-Pan Huang
ResearchOpen Access15 Oct 2021
Scientific Reports

Volume: 11, P: 1-13
SNORD11B-mediated 2′-O-methylation of primary let-7a in colorectal carcinogenesis

Zhixuan Bian
Chang Xu
Qiuhui Pan
Research24 Aug 2023
Oncogene

Volume: 42, P: 3035-3046
Correction: Protease Nexin I is a feedback regulator of EGF/ PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness

Tingting Tang
Qinhua Zhu
Liang Jin
Amendments and CorrectionsOpen Access06 Jan 2020
Cell Death & Disease

Volume: 11, P: 1-3
O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer

Guoqing Zhu
Abduh Murshed
Qiuhui Pan
ResearchOpen Access16 Apr 2021
Cell Death Discovery

Volume: 7, P: 1-12
Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness

Tingting Tang
Qinhua Zhu
Liang Jin
ResearchOpen Access09 Sept 2019
Cell Death & Disease

Volume: 10, P: 1-17
Inhibition of Cdk5 induces cell death of tumor-initiating cells

Melanie M Mandl
Siwei Zhang
Johanna Liebl
ResearchOpen Access21 Feb 2017
British Journal of Cancer

Volume: 116, P: 912-922

Search

AI-based large-scale screening of gastric cancer from noncontrast CT imaging

A Mendelian randomized study of circulating antioxidants in the diet and risk of cardiovascular disease

ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRs

Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging

Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma

Bandgap engineering of two-dimensional C₃N bilayers

Comprehensive analysis of senescence-related genes identifies prognostic clusters with distinct characteristics in glioma

O-GlcNAcylation of glutaminase isoform KGA inhibits ferroptosis through activation of glutaminolysis in hepatoblastoma

Inferring compound heterozygosity from large-scale exome sequencing data

Surface treatment of red painted and slipped wares in the middle Yangtze River valley of Late Neolithic China: multi-analytical case analysis

Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy

Human activities and species biological traits drive the long-term persistence of old trees in human-dominated landscapes

Will land transfer improve grain farmers’ adoption of agricultural green production technology? Evidence from Jiangxi Province, China

Changes and continuity in pottery production and use at Wujiafentou in the core zone of Youziling and Shijiahe cultures in central China

AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

Total morphosynthesis of biomimetic prismatic-type CaCO₃ thin films

Identify and validate circadian regulators as potential prognostic markers and immune infiltrates in head and neck squamous cell carcinoma

Identification and characterisation of lamprey protein kinase C delta-like gene

SNORA14A inhibits hepatoblastoma cell proliferation by regulating SDHB-mediated succinate metabolism

Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis

Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

Mitotic slippage is determined by p31^comet and the weakening of the spindle-assembly checkpoint

Dried blood sample analysis by antibody array across the total testing process

SNORD11B-mediated 2′-O-methylation of primary let-7a in colorectal carcinogenesis

Correction: Protease Nexin I is a feedback regulator of EGF/ PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness

O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer

Protease Nexin I is a feedback regulator of EGF/PKC/MAPK/EGR1 signaling in breast cancer cells metastasis and stemness

Inhibition of Cdk5 induces cell death of tumor-initiating cells

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