Respiratory viral infection causes fast onset of pathology, and is often compounded by vaccination-resistant variants. Here, the authors show that a STING agonist nanoparticle, termed NanoSTING, helps protect against SARS-CoV-2 in hamsters and influenza in mice, thereby implicating NanoSTING as a broad-spectrum treatment for respiratory viral infections.
- Ankita Leekha
- Arash Saeedi
- Navin Varadarajan
