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Advanced filters: Author: Syma Iqbal Clear advanced filters

  • Following progression on HER2-targeted first-line regimens, there are limited HER2-targeted therapies that have demonstrated efficacy in patients with gastroesophageal adenocarcinoma (GEA). Here, the authors report the results of a phase 1 clinical trial investigating zanidatamab (a HER2-targeted bispecific antibody) in heavily pre-treated patients with advanced or metastatic, HER2-expressing GEA.

    • Funda Meric-Bernstam
    • Sun Young Rha
    • Elena Elimova
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10