Cellular, molecular, and functional changes occur in the endothelium during ageing. Ungvari and colleagues explore the links between oxidative and nitrative stress and the conserved molecular pathways affecting endothelial dysfunction and impaired angiogenesis during ageing, and also speculate on how these pathological processes might be therapeutically targeted.
- Zoltan Ungvari
- Stefano Tarantini
- Anna Csiszar
