A metabolic engineering approach is used to re-engineer Escherichia coli so that it could produce higher alcohols from glucose, a renewable energy source. The strategy involves diverting intermediates in the amino acid biosynthetic pathway to synthesize the desired alcohol and may facilitate the large-scale production of biofuels via microbial fermentation.
- Shota Atsumi
- Taizo Hanai
- James C. Liao