Nature Search

Exceptionally low genomic diversity in the underutilised legume Kersting’s groundnut

Kersting’s groundnut is an underutilised crop that is locally important, tolerant to drought and critical to food security. Here, the authors report its genome assembly, population genetics analyses, and candidate genes for seed coat colour.

Tsz-Yan Cheung
Konoutan M. Kafoutchoni
Mark A. Chapman
ResearchOpen Access04 Jun 2025
Nature Communications

Volume: 16, P: 1-12
Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5

PAPD5 is responsible for adenylation of microRNAs. Here, the authors show that elevated level of PAPD5 enhances the adenylation and reduced expression of miR-7-5p. As a result, expression of TAB2, a target of miR-7-5p, is induced triggering neuronal apoptosis in Huntington’s disease.

Zhefan Stephen Chen
Shaohong Isaac Peng
Ho Yin Edwin Chan
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-18
A reference-grade wild soybean genome

Wild relatives of crop plants are invaluable germplasm for genetic improvement. Here, Xie et al. report a reference-grade wild soybean genome and show that it can be used to identify structural variation and refine quantitative trait loci.

Min Xie
Claire Yik-Lok Chung
Hon-Ming Lam
ResearchOpen Access14 Mar 2019
Nature Communications

Volume: 10, P: 1-12
Genome maps across 26 human populations reveal population-specific patterns of structural variation

Large structural variants (SV) are understudied in human genetics research because of the difficulty to detect them in the routinely generated short-read sequencing data. Here, the authors generate optical genome maps of 154 individuals from 26 populations that allow comprehensive examination of large SVs.

Michal Levy-Sakin
Steven Pastor
Pui-Yan Kwok
ResearchOpen Access04 Mar 2019
Nature Communications

Volume: 10, P: 1-14
Deep autoencoder for interpretable tissue-adaptive deconvolution and cell-type-specific gene analysis

Traditional bulk sequencing data lack information about cell-type-specific gene expression. Here, the authors develop a Tissue-AdaPtive autoEncoder (TAPE), a deep learning method connecting bulk RNA-seq and single-cell RNA-seq, and apply it to analyze the cell type fractions and cell-type-specific gene expression in clinical data.

Yanshuo Chen
Yixuan Wang
Yu Li
ResearchOpen Access08 Nov 2022
Nature Communications

Volume: 13, P: 1-17
Hypoxia causes transgenerational impairments in reproduction of fish

Hypoxia has diverse effects on aquatic life. Wang et al.show that reproductive defects resulting from hypoxia are epigenetically heritable in Japanese rice fish, and that this intergenerational inheritance is accompanied by differential methylation and gene expression in sperm.

Simon Yuan Wang
Karen Lau
Rudolf Shiu-Sun Wu
ResearchOpen Access04 Jul 2016
Nature Communications

Volume: 7, P: 1-9
Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing

The identification of genes that control economically important traits is an essential step towards crop improvement. Here the authors sequence the genome of the wild soybean and, through a combined genetic and functional approach, identify a new gene affecting salt tolerance in soybean.

Xinpeng Qi
Man-Wah Li
Hon-Ming Lam
ResearchOpen Access09 Jul 2014
Nature Communications

Volume: 5, P: 1-11
Author Correction: Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

Pui Yan Yeung
Jieyu Zhao
Chun Kit Kwok
Amendments and CorrectionsOpen Access26 Feb 2020
Scientific Reports

Volume: 10, P: 1-2
Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes

Jing-Woei Li
Heung-Man Lee
Ting-Fung Chan
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-14
Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

Pui Yan Yeung
Jieyu Zhao
Chun Kit Kwok
ResearchOpen Access30 May 2019
Scientific Reports

Volume: 9, P: 1-12
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments

Hao Qin
Norman Wai-Sing Lo
Ting-Fung Chan
ResearchOpen Access23 Feb 2018
Scientific Reports

Volume: 8, P: 1-11
Fine-tuning carbapenem resistance by reducing porin permeability of bacteria activated in the selection process of conjugation

Hoi-Kuan Kong
Qing Pan
Terrence Chi-Kong Lau
ResearchOpen Access15 Oct 2018
Scientific Reports

Volume: 8, P: 1-11
A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect

Chia-Hao Hsu
Ji-Sheng Lin
Yun-Jin Jiang
ResearchOpen Access03 Jun 2015
Scientific Reports

Volume: 5, P: 1-15
Transcriptomic responses of corpuscle of Stannius gland of Japanese eels (Anguilla japonica) to Changes in Water Salinity

Jie Gu
Jing-Woei Li
Chris Kong-Chu Wong
ResearchOpen Access24 Apr 2015
Scientific Reports

Volume: 5, P: 1-8

Search

Exceptionally low genomic diversity in the underutilised legume Kersting’s groundnut

Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5

A reference-grade wild soybean genome

Genome maps across 26 human populations reveal population-specific patterns of structural variation

Deep autoencoder for interpretable tissue-adaptive deconvolution and cell-type-specific gene analysis

Hypoxia causes transgenerational impairments in reproduction of fish

Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing

Author Correction: Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes

Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments

Fine-tuning carbapenem resistance by reducing porin permeability of bacteria activated in the selection process of conjugation

A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect

Transcriptomic responses of corpuscle of Stannius gland of Japanese eels (Anguilla japonica) to Changes in Water Salinity

Search

Quick links

Search

Filter By:

Search

Quick links