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Showing 1–50 of 132 results

Advanced filters: Author: Tony Hunter Clear advanced filters

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

Jonathan A. Cooper
Nachum A. Reiss
Tony Hunter
Research17 Mar 1983
Nature

Volume: 302, P: 218-223
Repeated plague infections across six generations of Neolithic Farmers

Population-scale ancient genomics are used to infer ancestry, social structure and pathogen infection in 108 Scandinavian Neolithic individuals from eight megalithic graves and a stone cist, showing that Neolithic plague was widespread.

Frederik Valeur Seersholm
Karl-Göran Sjögren
Martin Sikora
ResearchOpen Access10 Jul 2024
Nature

Volume: 632, P: 114-121
Role of Methionine in the Initiation of Haemoglobin Synthesis

RICHARD JACKSON
TONY HUNTER
Research15 Aug 1970
Nature

Volume: 227, P: 672-676
Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus

Daniel J. Donoghue
Crystal Anderson
Paul L. Kaplan
Research19 Apr 1984
Nature

Volume: 308, P: 748-750
Inactivation of p27^Kip1 by the viral E1A oncoprotein in TGFβ-treated cells

Asoke Mal
Randy Y. C. Poon
Marian L. Harter
Research21 Mar 1996
Nature

Volume: 380, P: 262-265
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

Wiebe Kruijer
Jonathan A. Cooper
Inder M. Verma
Research20 Dec 1984
Nature

Volume: 312, P: 711-716
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

Jonathon Pines
Tony Hunter
Research23 Aug 1990
Nature

Volume: 346, P: 760-763
B61 is a ligand for the ECK receptor protein-tyrosine kinase

Timothy D. Bartley
Robert W. Hunt
Gary M. Fox
Research07 Apr 1994
Nature

Volume: 368, P: 558-560
Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration

Loss-of-function variants in thyroid hormone transporter MCT8 cause a neurodevelopmental and metabolic disorder. Here the authors identify genotype-phenotype relationships, advance insights in MCT8 (dys)function and create a pathogenicity-severity variant classifier.

Stefan Groeneweg
Ferdy S. van Geest
W. Edward Visser
ResearchOpen Access12 Mar 2025
Nature Communications

Volume: 16, P: 1-21
A growing coactivator network

Ralf Janknecht
Tony Hunter
News & Views05 Sept 1996
Nature

Volume: 383, P: 22-23
Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization

Alexandrine M. Bilwes
Jeroen den Hertog
Joseph P. Noel
Research08 Aug 1996
Nature

Volume: 382, P: 555-559
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

Tony Hunter
Nicholas Ling
Jonathan A. Cooper
Research04 Oct 1984
Nature

Volume: 311, P: 480-483
The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 ___domain in vivo reducing peptide ligand binding

Martin A Broome
Tony Hunter
Research09 Jan 1997
Oncogene

Volume: 14, P: 17-34
Allelic Variants in the Amino-acid Sequence of the α Chain of Rabbit Haemoglobin

TONY HUNTER
ALAN MUNRO
Research20 Sept 1969
Nature

Volume: 223, P: 1270-1272
A human peptidyl–prolyl isomerase essential for regulation of mitosis

Kun Ping Lu
Steven D. Hanes
Tony Hunter
Research11 Apr 1996
Nature

Volume: 380, P: 544-547
Radioactive protein-labelling techniques

JILL MEISENHELDER
TONY HUNTER
Research08 Sept 1988
Nature

Volume: 335, P: 120
Messenger RNA for the coat protein of tobacco mosaic virus

Tony R. Hunter
Tim Hunt
David Zimmern
Research01 Apr 1976
Nature

Volume: 260, P: 759-764
Growth factors: The epidermal growth factor receptor gene and its product

Tony Hunter
News & Views04 Oct 1984
Nature

Volume: 311, P: 414-416
Cell-surface proteins: At last the insulin receptor

Tony Hunter
News & Views28 Feb 1985
Nature

Volume: 313, P: 740-741
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation ___domain

Christian Trautwein
Carme Caelles
Mario Chojkier
Research05 Aug 1993
Nature

Volume: 364, P: 544-547
Isolation and characterization of human calcitonin gene-related peptide

Howard R. Morris
Maria Panico
Iain MacIntyre
Research19 Apr 1984
Nature

Volume: 308, P: 746-748
Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells

Takeshi Sekiguchi
Tony Hunter
Research26 Jan 1998
Oncogene

Volume: 16, P: 369-380
Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

Christine Ellis
Michael Moran
Tony Pawson
Research25 Jan 1990
Nature

Volume: 343, P: 377-381
Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

Tony Kouzarides
Edward Ziff
Research17 Aug 1989
Nature

Volume: 340, P: 568-571
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

Here, the authors demonstrate that inhibition of PTP1B and PTPN2 in tumor cells and T-cells with a small molecule inhibitor represses the growth of immunogenic and cold tumors, and enhances response to anti-PD-1 immunotherapy without promoting immune-related toxicities.

Shuwei Liang
Eric Tran
Tony Tiganis
ResearchOpen Access27 Jul 2023
Nature Communications

Volume: 14, P: 1-27
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

David D. Schlaepfer
Steven K. Hanks
Peter van der Geer
Research29 Dec 1994
Nature

Volume: 372, P: 786-791
MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB

Amino acids stimulate cell growth and depletion in a cell activates autophagy, yet how this is regulated is unclear. Here, the authors show that MAP4K3 (also known as germinal-center kinase-like kinase) acts as an amino acid-dependent regulator of autophagy, via phosphorylation of the transcription factor EB.

Cynthia L. Hsu
Elian X. Lee
Albert R. La Spada
ResearchOpen Access05 Mar 2018
Nature Communications

Volume: 9, P: 1-15
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement

Mark A. Verdecia
Han-kuei Huang
Joseph P. Noel
Research01 Jul 2000
Nature Structural Biology

Volume: 7, P: 602-608
Getting down to specifics

Tony Pawson
News & Views09 Feb 1995
Nature

Volume: 373, P: 477-478
Expression of a novel form of p21^Cip1/Waf1 in UV-irradiated and transformed cells

Randy YC Poon
Tony Hunter
Research19 Mar 1998
Oncogene

Volume: 16, P: 1333-1343
Look at a tyrosine kinase

Tony Pawson
News & Views29 Dec 1994
Nature

Volume: 372, P: 726-727
Cytokine connections

Tony Hunter
News & Views11 Nov 1993
Nature

Volume: 366, P: 114-115
Anti-phosphatases take the stage

Hunter Tony
News & Views01 Apr 1998
Nature Genetics

Volume: 18, P: 303-305
Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

Peter Angel
Elizabeth A. Allegretto
Michael Karin
Research10 Mar 1988
Nature

Volume: 332, P: 166-171
Identification of nine new susceptibility loci for endometrial cancer

Endometrial cancer is the most common invasive gynaecological cancer in developed countries. Here a meta-analysis identifies an additional nine novel endometrial cancer risk loci and eQTL analysis reveals risk variants associate with reduced expression of negative regulators of oncogenic signal transduction proteins.

Tracy A. O’Mara
Dylan M. Glubb
Deborah J. Thompson
ResearchOpen Access09 Aug 2018
Nature Communications

Volume: 9, P: 1-12
Proteins suggest form of their own database

Marvin Cassman
Tony Hunter
Tony Pawson
Correspondence10 Feb 2000
Nature

Volume: 403, P: 591-592
Monitoring plan gets low marks, low budget

Tony Reichhardt
News06 Apr 1995
Nature

Volume: 374, P: 486
Cancer: Cell growth control mechanisms

Tony Hunter
News & Views03 Jul 1986
Nature

Volume: 322, P: 14-15
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Yu Shi
Weina Gao
Tony Hunter
Amendments and Corrections30 Nov 2021
Nature

Volume: 600, P: E18
Clinical functional proteomics of intercellular signalling in pancreatic cancer

TMEPro profiles the glycosylated secreted and plasma membrane proteome of 100 human pancreatic tissue samples, defines cell type origins and identifies potential paracrine cross-talk mediated through tyrosine phosphorylation.

Peiwu Huang
Weina Gao
Ruijun Tian
Research13 Nov 2024
Nature

Volume: 637, P: 726-735
Rapid rates of growth and collapse of Monowai submarine volcano in the Kermadec Arc

The vast majority of Earth’s volcanoes are under water, but little is known of the structure and evolution of submarine volcanoes. A bathymetric survey mapping the Monowai submarine volcano in the Tonga–Kermadec Arc twice within 14 days reveals dramatic changes in bathymetry of up to 71.9 m, associated with volcanic activity.

A. B. Watts
C. Peirce
C. E. J. de Ronde
Research13 May 2012
Nature Geoscience

Volume: 5, P: 510-515
Correction: Corrigendum: Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

Chinnaswamy Jagannath
Devin R Lindsey
N Tony Eissa
Amendments and Corrections01 Jul 2010
Nature Medicine

Volume: 16, P: 828
Correction: Corrigendum: Structure-based prediction of protein–protein interactions on a genome-wide scale

Qiangfeng Cliff Zhang
Donald Petrey
Barry Honig
Amendments and Corrections06 Mar 2013
Nature

Volume: 495, P: 127
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Treatment with a specific inhibitor of the N⁶-methyladenosine methyltransferase METTL3 leads to reduced growth of cancer cells, indicating the potential of approaches targeting RNA-modifying enzymes for anticancer therapy.

Eliza Yankova
Wesley Blackaby
Tony Kouzarides
Research26 Apr 2021
Nature

Volume: 593, P: 597-601
Author Correction: π-HuB: the proteomic navigator of the human body

Fuchu He
Ruedi Aebersold
Zemin Zhang
Amendments and Corrections23 Dec 2024
Nature

Volume: 637, P: E22
Mapping genomic loci implicates genes and synaptic biology in schizophrenia

A genome-wide association study including over 76,000 individuals with schizophrenia and over 243,000 control individuals identifies common variant associations at 287 genomic loci, and further fine-mapping analyses highlight the importance of genes involved in synaptic processes.

Vassily Trubetskoy
Antonio F. Pardiñas
Jim van Os
Research08 Apr 2022
Nature

Volume: 604, P: 502-508
Five endometrial cancer risk loci identified through genome-wide association analysis

Amanda Spurdle, Ian Tomlinson, Douglas Easton and colleagues conduct a GWAS meta-analysis and identify five new risk loci for endometrial cancer. Functional studies show that one risk-associated SNP is located in an active chromatin region that interacts with the KLF5 promoter.

Timothy H T Cheng
Deborah J Thompson
Amanda B Spurdle
Research02 May 2016
Nature Genetics

Volume: 48, P: 667-674
NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia

NME3 is a member of NDPK family. Here, Chen et. al., discover that histidine phosphorylatable NME3 is required for hypoxia-induced mitophagy via PA-dependent interaction with Drp1, which is protected from MUL1-mediated ubiquitination for mitophagy.

Chih-Wei Chen
Chi Su
Zee-Fen Chang
ResearchOpen Access13 Mar 2024
Nature Communications

Volume: 15, P: 1-20
A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans

The ubiquitin ligase WWP-1 mediates the lifespan-increasing effect of dietary restriction (DR) in worms. Here the authors show that WWP-1 mono-ubiquitinylates the transcription factor Klf-1 in cultured cells and demonstrate that WWP-1 acts upstream of Klf-1 to regulate DR-induced longevity in worms.

Andrea C. Carrano
Andrew Dillin
Tony Hunter
Research08 May 2014
Nature Communications

Volume: 5, P: 1-9
New impressions of Src and Hck

Tony Pawson
News & Views13 Feb 1997
Nature

Volume: 385, P: 583-585

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