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Showing 101–132 of 132 results

Advanced filters: Author: Tony Hunter Clear advanced filters

Social and environmental risk factors in the emergence of infectious diseases

Robin A Weiss
Anthony J McMichael
Reviews01 Dec 2004
Nature Medicine

Volume: 10, P: S70-S76
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng
Deborah Thompson
Ian Tomlinson
ResearchOpen Access01 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Selective deforestation and exposure of African wildlife to bat-borne viruses

A study in Uganda found that local extirpation of a mineral-rich tree species used in tobacco farming forced wildlife to obtain minerals by eating bat guano, in which 27 eukaryotic viruses were identified, including a novel betacoronavirus.

Pawel Fedurek
Caroline Asiimwe
Tony L. Goldberg
ResearchOpen Access22 Apr 2024
Communications Biology

Volume: 7, P: 1-7
Whole exome and genome sequencing in mendelian disorders: a diagnostic and health economic analysis

Lisa J. Ewans
Andre E. Minoche
Tony Roscioli
ResearchOpen Access15 Aug 2022
European Journal of Human Genetics

Volume: 30, P: 1121-1131
Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAF_II250 mutation

Takeshi Sekiguchi
Takeharu Nishimoto
Tony Hunter
Research15 Mar 1999
Oncogene

Volume: 18, P: 1797-1806
A framework for advancing our understanding of cancer-associated fibroblasts

This Consensus Statement highlights the importance of cancer-associated fibroblasts in cancer biology and progression, and issues a call to action for all cancer researchers to standardize assays and report metadata in studies of cancer-associated fibroblasts to advance our understanding of this important cell type in the tumour microenvironment.

Erik Sahai
Igor Astsaturov
Zena Werb
ReviewsOpen Access24 Jan 2020
Nature Reviews Cancer

Volume: 20, P: 174-186
Two truncating variants in FANCC and breast cancer risk

Thilo Dörk
Paolo Peterlongo
Douglas F. Easton
ResearchOpen Access29 Aug 2019
Scientific Reports

Volume: 9, P: 1-14
Overview of the Alliance for Cellular Signaling

Alfred G. Gilman
Melvin I. Simon
Gilberto R. Sambrano
Editorial12 Dec 2002
Nature

Volume: 420, P: 703-706
The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

Robert J Ingham
Gerald Gish
Tony Pawson
Reviews15 Mar 2004
Oncogene

Volume: 23, P: 1972-1984
A craniosynostosis massively parallel sequencing panel study in 309 Australian and New Zealand patients: findings and recommendations

Eric Lee
Trang Le
Tony Roscioli
Research07 Dec 2017
Genetics in Medicine

Volume: 20, P: 1061-1068
Desert crossing strategies of migrant songbirds vary between and within species

Frédéric Jiguet
Malcolm Burgess
Chris Hewson
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-12
Higher consumption of ultra-processed foods and increased likelihood of central nervous system demyelination in a case-control study of Australian adults

Adriana Mannino
Alison Daly
Lucinda J. Black
ResearchOpen Access08 Feb 2023
European Journal of Clinical Nutrition

Volume: 77, P: 611-614
Biodiversity of protists and nematodes in the wild nonhuman primate gut

Allison E. Mann
Florent Mazel
Laura Wegener Parfrey
ResearchOpen Access12 Nov 2019
The ISME Journal

Volume: 14, P: 609-622
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

Phosphorylation is a universal regulatory mechanism that induces changes in protein conformation. However, certain phosphorylated motifs can be further regulated by the prolyl isomerase PIN1, which is of increasing importance in aspects of physiology and disease.

Kun Ping Lu
Xiao Zhen Zhou
Reviews01 Nov 2007
Nature Reviews Molecular Cell Biology

Volume: 8, P: 904-916
The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target

This Review discusses PIN1-catalysed prolyl isomerization as a common signalling mechanism to regulate the balance of oncogenes and tumour suppressors. PIN1 inhibitors may be able to restore the balance in cancer cells and cancer stem cells to treat aggressive and drug-resistant tumours.

Xiao Zhen Zhou
Kun Ping Lu
Reviews03 Jun 2016
Nature Reviews Cancer

Volume: 16, P: 463-478
An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice

Arshad Khan
Pearl Bakhru
Chinnaswamy Jagannath
ResearchOpen Access05 Aug 2019
npj Vaccines

Volume: 4, P: 1-19
Mesenchymal stem cells internalize Mycobacterium tuberculosis through scavenger receptors and restrict bacterial growth through autophagy

Arshad Khan
Lovepreet Mann
Chinnaswamy Jagannath
ResearchOpen Access08 Nov 2017
Scientific Reports

Volume: 7, P: 1-15
Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes

Katherine R. Amato
Jon G. Sanders
Steven R. Leigh
Research11 Jul 2018
The ISME Journal

Volume: 13, P: 576-587
Neonatal adaptive immunity comes of age

Becky Adkins
Claude Leclerc
Stuart Marshall-Clarke
Reviews01 Jul 2004
Nature Reviews Immunology

Volume: 4, P: 553-564
Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology

Anaplastic lymphoma kinase (ALK) is commonly altered — through mutation, overexpression or translocation — in many types of cancer, but the role of ALK signalling in mammalian cells and tumours remains enigmatic. What can we learn from model systems? And what progress has been made in targeting this receptor tyrosine kinase?

Bengt Hallberg
Ruth H. Palmer
Reviews24 Sept 2013
Nature Reviews Cancer

Volume: 13, P: 685-700
Focal adhesion kinase: in command and control of cell motility

Satyajit K. Mitra
Daniel A. Hanson
David D. Schlaepfer
Reviews01 Jan 2005
Nature Reviews Molecular Cell Biology

Volume: 6, P: 56-68
Cubism and the cell cycle: the many faces of the APC/C

The APC/C (anaphase-promoting complex, also known as the cyclosome) is an E3 ubiquitin ligase that ensures temporal order of the cell cycle by degrading different cell cycle regulators at specific time points. Recent studies have provided insights into how the APC/C recognizes its substrates and how it is itself regulated.

Jonathon Pines
Reviews02 Jun 2011
Nature Reviews Molecular Cell Biology

Volume: 12, P: 427-438
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism

Xinde Zheng
Tony Hunter
Research14 May 2013
Cell Research

Volume: 23, P: 886-897
Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

Debra Van Egeren
Khushi Kohli
Zenta Walther
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-6
Hunting down bacterial resistance

Anti-infective company VenatoRx Pharmaceuticals has developed injectable and orally bioavailable broad-spectrum antibiotics that could help curb the expansion of antimicrobial resistance. The company is now seeking clinical and commercial partnerships.

VenatoRx Pharmaceuticals
Advertorial04 Jul 2018
Biopharma Dealmakers
Histidine kinases and the missing phosphoproteome from prokaryotes to eukaryotes

Kevin Adam
Tony Hunter
Research23 Oct 2017
Laboratory Investigation

Volume: 98, P: 233-247
How phosphoubiquitin activates Parkin

A recent report, solving the structure of a Parkin-phosphoubiquitin complex, greatly advances the understanding of the Parkin activation mechanism.

Xinde Zheng
Tony Hunter
Research Highlights11 Aug 2015
Cell Research

Volume: 25, P: 1087-1088
Post-exposure treatment of non-human primates lethally infected with Ebola virus with EBOTAb, a purified ovine IgG product

Stuart D. Dowall
Frédéric Jacquot
Miles W. Carroll
ResearchOpen Access22 Jun 2017
Scientific Reports

Volume: 7, P: 1-15
Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer

Bo Gao
Amanda Russell
Anna deFazio
ResearchOpen Access09 May 2014
Scientific Reports

Volume: 4, P: 1-9
Emerging functions of branched ubiquitin chains

Michael E. French
Chad F. Koehler
Tony Hunter
ReviewsOpen Access26 Jan 2021
Cell Discovery

Volume: 7, P: 1-10
Prolyl isomerase Pin1 in cancer

Zhimin Lu
Tony Hunter
Reviews15 Aug 2014
Cell Research

Volume: 24, P: 1033-1049
A systematic review of optical coherence tomography findings in adults with mild traumatic brain injury

Hannah S. Lyons
Matilde Sassani
Richard J. Blanch
ReviewsOpen Access18 Jan 2024
Eye

Volume: 38, P: 1077-1083

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