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The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine

The neuronal composition of the intestinal submucosal plexus is incompletely understood. Here Li et al. define their neuron classes, connectome and stepwise acquisition of identities.

Wei Li
Khomgrit Morarach
Ulrika Marklund
ResearchOpen Access29 May 2025
Nature Neuroscience

Volume: 28, P: 1146-1159
Lmx1b is essential for the development of serotonergic neurons

Yu-Qiang Ding
Ulrika Marklund
Zhou-Feng Chen
Research03 Aug 2003
Nature Neuroscience

Volume: 6, P: 933-938
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing

Imaging and transcriptomic approaches to investigate mouse enteric nervous system diversity and development reveal a new classification of intestinal myenteric neurons and a novel principle of neuronal diversification by postmitotic transitions.

Khomgrit Morarach
Anastassia Mikhailova
Ulrika Marklund
Research07 Dec 2020
Nature Neuroscience

Volume: 24, P: 34-46
Diversity, development and immunoregulation of enteric neurons

In 2021, transcriptome analysis of the mouse and human gut advanced our understanding of the cellular composition, development and surrounding non-neural context of the enteric nervous system (ENS). A role for the ENS in tuning regulatory T cell proportions contributed insights into the dependency between the ENS, immune system and microbiota.

Ulrika Marklund
News & Views12 Nov 2021
Nature Reviews Gastroenterology & Hepatology

Volume: 19, P: 85-86
Ernest Arenas (1962–2024)

Ernest Arenas, Professor at the Karolinska Institutet, passed away on 15 September 2024 at the age of 62 in Stockholm, Sweden. Ernest made unique contributions to the field of Parkinson’s disease research, with a strong commitment to developing improved treatment strategies through cell replacement therapy.

Patrik Ernfors
Gonçalo Castelo-Branco
Onur Dagliyan
Comments & Opinion28 Oct 2024
Nature Neuroscience

Volume: 27, P: 2267-2268
Neurosurgical untethering with or without syrinx drainage results in high patient satisfaction and favorable clinical outcome in post-traumatic myelopathy patients

Ulrika Holmström
Parmenion P. Tsitsopoulos
Niklas Marklund
Research27 Mar 2018
Spinal Cord

Volume: 56, P: 873-882
Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Bastien Paré
Manuela Lehmann
François Gros-Louis
ResearchOpen Access21 Sept 2018
Scientific Reports

Volume: 8, P: 1-13
Gait training after spinal cord injury: safety, feasibility and gait function following 8 weeks of training with the exoskeletons from Ekso Bionics

Carsten Bach Baunsgaard
Ulla Vig Nissen
Fin Biering-Sørensen
Research06 Nov 2017
Spinal Cord

Volume: 56, P: 106-116

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The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine

Lmx1b is essential for the development of serotonergic neurons

Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing

Diversity, development and immunoregulation of enteric neurons

Ernest Arenas (1962–2024)

Neurosurgical untethering with or without syrinx drainage results in high patient satisfaction and favorable clinical outcome in post-traumatic myelopathy patients

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis

Gait training after spinal cord injury: safety, feasibility and gait function following 8 weeks of training with the exoskeletons from Ekso Bionics

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