Nature Search

Prostate-cancer link sours IGF-1

Vicki Brower
Research01 Mar 1998
Nature Biotechnology

Volume: 16, P: 223
Acute regulation of murine adipose tissue lipolysis and insulin resistance by the TGFβ superfamily protein GDF3

TGFβ superfamily proteins can affect cellular differentiation, thermogenesis, and fibrosis in mammalian adipose tissue. Here the authors described a role for the TGFβ superfamily protein GDF3 in the regulation of lipolysis, glucose tolerance and glycemic variability in mice.

Nagasuryaprasad Kotikalapudi
Deepti Ramachandran
Alexander S. Banks
ResearchOpen Access13 May 2025
Nature Communications

Volume: 16, P: 1-20
Development of Heart Rate Variation Over the First 6 Months of Life in Normal Infants

Vicki L Schechtman
Ronald M Harper
Karen A Kluge
Research01 Oct 1989
Pediatric Research

Volume: 26, P: 343-346
Widespread misestimates of greenhouse gas emissions suggest low carbon competence

Individual actions are important to reduce emissions, yet consumers’ carbon incompetence may lead to ineffective efforts. This study demonstrates the consistent inaccuracy in assessing emissions of behaviours, firms and industries, which may be driven by lack of information or expertise.

Eric J. Johnson
Eli Rosen Sugerman
Michael W. Morris
Research21 Jun 2024
Nature Climate Change

Volume: 14, P: 707-714
Author Correction: Joint disease-specificity at the regulatory base-pair level

Pushpanathan Muthuirulan
Dewei Zhao
Terence D. Capellini
Amendments and CorrectionsOpen Access27 Jan 2022
Nature Communications

Volume: 13, P: 1
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

Harry Pickering
Joanna Schaenman
Charles R. Langelier
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-16
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Post-acute sequelae of SARS-CoV-2 (PASC) is still not well understood. Here the authors provide patient reported outcomes from 590 hospitalized COVID-19 patients and show association of PASC with higher respiratory SARS-CoV-2 load and circulating antibody titers, and in some an elevation in circulating fibroblast growth factor 21.

Al Ozonoff
Naresh Doni Jayavelu
Nadine Rouphael
ResearchOpen Access03 Jan 2024
Nature Communications

Volume: 15, P: 1-17
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing

Kunikazu Tsuji
Amitabha Bandyopadhyay
Vicki Rosen
Research12 Nov 2006
Nature Genetics

Volume: 38, P: 1424-1429
Bone morphogenetic protein-3 is a negative regulator of bone density

Aaron Daluiski
Thomas Engstrand
Karen M. Lyons
Research01 Jan 2001
Nature Genetics

Volume: 27, P: 84-88
A FoxA2+ long-term stem cell population is necessary for growth plate cartilage regeneration after injury

The growth plate cartilage supports long bone growth. Here the authors identify FoxA2+ long term stem cells in the growth plate that are stratified with short term PTHrP+ cells, participate in production of hyaline cartilage, expand in response to trauma, and whose ablation impairs cartilage regeneration.

Shanmugam Muruganandan
Rachel Pierce
Andreia M. Ionescu
ResearchOpen Access06 May 2022
Nature Communications

Volume: 13, P: 1-15
BMP signalling in skeletal development, disease and repair

Bone morphogenetic proteins (BMPs) have been implicated in almost all aspects of bone, cartilage and joint biology. Here, Valerie Salazar and colleagues discuss BMP superfamily signalling in the context of skeletal development and joint morphogenesis, and summarize the status of the BMP pathway as a therapeutic target for treating skeletal trauma and disease.

Valerie S. Salazar
Laura W. Gamer
Vicki Rosen
Reviews19 Feb 2016
Nature Reviews Endocrinology

Volume: 12, P: 203-221
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

The role of IgG glycosylation in the immune response has been studied, but less is known about IgM glycosylation. Here the authors characterize glycosylation of SARS-CoV-2 spike specific IgM and show that it correlates with COVID-19 severity and affects complement deposition.

Benjamin S. Haslund-Gourley
Kyra Woloszczuk
Mary Ann Comunale
ResearchOpen Access09 Jan 2024
Nature Communications

Volume: 15, P: 1-19
Joint disease-specificity at the regulatory base-pair level

While many genetic loci have been found to be associated with disease, not many have had their causal variants and mechanisms investigated. Here, the authors experimentally dissect two loci near GDF5 which are associated with two different joint disorders and which map to independent regulatory elements.

Pushpanathan Muthuirulan
Dewei Zhao
Terence D. Capellini
ResearchOpen Access06 Jul 2021
Nature Communications

Volume: 12, P: 1-16
Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3

Malcolm Whitman
Vicki Rosen
Thomas Mueller
Correspondence08 Jul 2013
Nature Medicine

Volume: 19, P: 809-810
Serotonin 2A −1438 G/A and G-Protein Beta3 Subunit C825T Polymorphisms in Patients with Depression and SSRI-Associated Sexual Side-Effects

Jeffrey R Bishop
Jessica Moline
Anita H Clayton
Research10 May 2006
Neuropsychopharmacology

Volume: 31, P: 2281-2288
A novel methodology utilizing microchip implants to monitor individual activity and body temperature for assessing knee pain in group-housed rats

Shoichi Hasegawa
Riko Yamashita
Kunikazu Tsuji
ResearchOpen Access23 Jul 2024
Scientific Reports

Volume: 14, P: 1-13
Correction: Corrigendum: NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase

Vincent Kuek
Zhifan Yang
Jiake Xu
Amendments and CorrectionsOpen Access21 Nov 2016
Scientific Reports

Volume: 6, P: 1
NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase

Vincent Kuek
Zhifan Yang
Jiake Xu
ResearchOpen Access26 Oct 2016
Scientific Reports

Volume: 6, P: 1-13

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