Cell-cell adhesion by desmosomes is weakened in the blistering skin disease pemphigus vulgaris. Here, authors found that the transcription factor Kruppel-like factor 5 is essential for the expression of the desmosomal gene desmoglein 3 and suggest a novel treatment approach.
- Henriette Franz
- Maitreyi Rathod
- Volker Spindler