A low toxicity and high efficiency nucleic acid delivery system is the key to the successful implementation of gene therapy. In this study, a novel fluorinated polycationic carrier was used to effectively inhibit tumor growth by targeting VEGF genes with RNAi technology based on its unique fluorine effect, providing a feasible strategy for future clinical solid tumor treatment.
- Zihan Yuan
- Xiaoshuang Guo
- Wei-En Yuan
