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Mantle flows driving tectonic escape around eastern Himalaya syntaxis

Rui Qu
Ye Zhu
Shoichi Yoshioka
ResearchOpen Access26 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Non-nucleotide stimulators of interferon gene (STING) agonists hold great promise as the immunotherapeutic agents for cancer therapy. Here, this group reports incorporating STING agonist MSA-2 and DOX in the separate layers of 3D-printed polymeric scaffold for effectively activating STING-IFNβ pathway, enhancing DAMPs release thereby suppressing postsurgical tumor recurrence and metastasis.

Kai Li
Xuan Yu
Mingqiang Li
ResearchOpen Access14 Feb 2025
Nature Communications

Volume: 16, P: 1-26
Research on driving factors of consumer purchase intention of artificial intelligence creative products based on user behavior

Weiling Shi
Li Li
Junjie Li
ResearchOpen Access19 May 2025
Scientific Reports

Volume: 15, P: 1-23
Decoding the m⁶A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach

RNA modifications like m6A are vital for gene expression but challenging to detect at single-base resolution. Here, the authors introduce pum6a, an advanced computational framework, to enable precise single-base m6A detection and uncovering regulatory mechanisms in hypoxic cancer cells.

Chuwei Liu
Heng Liang
Guohui Wan
ResearchOpen Access18 Jan 2025
Nature Communications

Volume: 16, P: 1-15
A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening

Polygenic Risk Scores (PRS) show promise for facilitating cancer risk stratification. Here, the authors performed a large genome-wide association study and develop a PRS for nasopharyngeal carcinoma, which could improve risk stratification and personalized screening.

Yong-Qiao He
Tong-Min Wang
Wei-Hua Jia
ResearchOpen Access12 Apr 2022
Nature Communications

Volume: 13, P: 1-10
Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47

Jin and colleagues show that myeloid cells in patients with colorectal cancer exhibit increased expression of SIRPA and that Sirpa deficiency on macrophages reprograms the tumor microenvironment and enhances the function of antitumor CD8⁺ T cells.

Chunliu Huang
Xuefei Wang
Wenfei Jin
Research10 Jan 2024
Nature Cancer

Volume: 5, P: 500-516
Climate warming accelerates temporal scaling of grassland soil microbial biodiversity

Using a multifactorial global change experiment, the authors show that warming grassland plots by +3 °C over 6 years accelerates the scaling rate of both taxonomic and phylogenetic diversity in soil bacterial and fungal communities.

Xue Guo
Xishu Zhou
Jizhong Zhou
Research25 Mar 2019
Nature Ecology & Evolution

Volume: 3, P: 612-619
CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome

Yihua Huang
Zirui Chen
Yafang Hu
ResearchOpen Access12 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-13
Bio-Source of di-n-butyl phthalate production by filamentous fungi

Congkui Tian
Jinren Ni
Yiping Wang
ResearchOpen Access09 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Single-cell sequencing reveals increased LAMB3-positive basal keratinocytes and ZNF90-positive fibroblasts in autologous cultured epithelium

Autologous serum- and feeder-free cultured epithelium showcases comparable efficacy, increased safety over serum- and feeder-dependent epithelium, revealing the role of LAMB3+ keratinocytes and ZNF90+ fibroblasts in vitiligo.

Weiling Lian
Xuanhao Zeng
Jinhua Xu
ResearchOpen Access10 Jan 2024
Communications Biology

Volume: 7, P: 1-13
METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stability

Zhuojia Chen
Jiawang Zhou
Hongsheng Wang
Research15 Feb 2024
Oncogene

Volume: 43, P: 976-991
VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression

Jing Ji
Yuxin Xu
Bin Liu
ResearchOpen Access04 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-10
Metabolism-regulated ferroptosis in cancer progression and therapy

Lvlan Ye
Xiangqiong Wen
Weiling He
ReviewsOpen Access08 Mar 2024
Cell Death & Disease

Volume: 15, P: 1-12
Assessment of predictive validity and feasibility of Edmonton Frail Scale in identifying postoperative complications among elderly patients: a prospective observational study

Yingke He
Lydia Weiling Li
Hairil Rizal Abdullah
ResearchOpen Access07 Sept 2020
Scientific Reports

Volume: 10, P: 1-10
Metabolic rates of giant pandas inform conservation strategies

Yuxiang Fei
Rong Hou
Zhihe Zhang
ResearchOpen Access06 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
New insights into the correlations between circulating tumor cells and target organ metastasis

Qinru Zhan
Bixia Liu
Zunfu Ke
ReviewsOpen Access21 Dec 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-23

Search

Mantle flows driving tectonic escape around eastern Himalaya syntaxis

Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Research on driving factors of consumer purchase intention of artificial intelligence creative products based on user behavior

Decoding the m⁶A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach

A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening

Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47

Climate warming accelerates temporal scaling of grassland soil microbial biodiversity

CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome

Bio-Source of di-n-butyl phthalate production by filamentous fungi

Single-cell sequencing reveals increased LAMB3-positive basal keratinocytes and ZNF90-positive fibroblasts in autologous cultured epithelium

METTL3 promotes cellular senescence of colorectal cancer via modulation of CDKN2B transcription and mRNA stability

VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression

Metabolism-regulated ferroptosis in cancer progression and therapy

Assessment of predictive validity and feasibility of Edmonton Frail Scale in identifying postoperative complications among elderly patients: a prospective observational study

Metabolic rates of giant pandas inform conservation strategies

New insights into the correlations between circulating tumor cells and target organ metastasis

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