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Aqueous and non-aqueous Li-based electrolyte solutions have narrow electrochemical stability windows, which hinder the operation of batteries at high cell potentials. Here, to circumvent this limitation, the authors propose the combined use of tailored aqueous and non-aqueous electrolyte solutions in various Li-based cell configurations.

The inclusion of a Mg–Bi-based interlayer between the lithium metal and solid electrolyte and a F-rich interlayer on the cathode improves the stability and performance of solid-state lithium-metal batteries.

Solid-state electrolyte reduction and Li dendrite growth limit the stability of all-solid-state Li metal batteries. Here the authors show that reductive electrophiles gain electrons and metal cations from metal–nucleophile materials on contact, allowing the electrochemical formation of a dense, electron-blocking film that improves the stability of both the anode and high-voltage cathode.

All-solid-state lithium-metal batteries are at the forefront of battery research and development. Here C. Wang and colleagues have developed an interlayer design strategy to address issues associated with lithium dendrite growth and interface resistance, resulting in substantial improvements in battery performance.

The critical current density is generally used to evaluate dendrite-suppression capability in batteries. Here the authors propose a critical interphase overpotential descriptor for dendrite suppression and demonstrate high-performance solid-state battery design with the new descriptor.

Micro-sized silicon are promising anode materials due to low-cost and high-energy, yet their application is hindered by inaccessible electrolytes. Here, the authors report sulfolane-based electrolytes that form silicon-phobic interphases and enable high-voltage pouch cells to achieve superior cycle life.

Batteries with solid polymer electrolytes face challenges in electrochemical stability and compatibility with high-voltage cathodes. Chunsheng Wang and colleagues have developed a polymer blend with a high Li salt concentration that enhances the stability of solid polymer electrolytes and achieves promising electrochemical performance in full-cell applications.

Micro-sized alloying anodes in Li-ion batteries cost less and offer higher capacity than graphite but suffer from cyclability issues. Chunsheng Wang and colleagues develop asymmetric electrolytes for micro-sized Si, Al, Sn and Bi anodes using solvent-free ionic liquids and molecular solvents to tackle the issue.

Lithium metal batteries are an attractive energy storage technology, but their development relies on the complex interplay between the components’ chemical, physical and mechanical properties. Now, selective methylation of dimethoxyethane ether electrolytes is shown to improve electrolyte, electrode and solid–electrolyte interphase stabilities to enable high-performance 4.3 V lithium metal batteries.

This study reveals that RNA silencing component Argonaute 2 (AGO2) loads small RNAs at endoplasmic reticulum–chloroplast membrane contact sites with the help of RNA helicase 3 (RH3), which also enhances the loading of viral-derived small RNAs. These findings highlight the connections between RNA silencing, viral replication, and plant antiviral resistance.

The commercialization of light-emitting diodes based on emissive quantum dots (e.g. QLEDs) is hindered by their inherent poor operational lifetime. Using an intelligent energy-level design strategy, Qian et al. demonstrate QLEDs with operational lifetime that meets industrial display standards.

For electrochromic materials to reach their full potential for high efficiency bistable displays, technical challenges related to their underlying mechanism must be addressed. Here, the authors, through intelligent molecular design, report a solid bistable device with state-of-the-art performance.

The cryo-electron microscopy structure of the Polycomb repressive deubiquitinase (PR-DUB) in complex with the H2AK119ub1 nucleosome provides insight into how the substrate specificity of PR-DUB is achieved.

Precise coupling of different or even contradictory material properties and biological characteristics is needed for tissue engineering but challenging. Here the authors report an all-in-one guided bone regeneration membrane that asymmetrically combines stiffness and flexibility, ingrowth barrier and ingrowth guiding, alongside anti-bacteria and cell-activation.

Renal tubular atrophy is a hallmark of chronic kidney disease. The study by Zhu et al. reveals the protective role of tubular polynucleotide phosphorylase (PNPT1) against renal atrophy by blocking the leakage of mitochondrial dsRNAs into cytoplasm where they activate the PKReIF2α axis and terminate translation.

Epidemics often exhibit drastic dynamics, unmatched by percolation theory—a difference that may be due to cooperation between contagions. A mechanistic model implicates network topology in regulating the efficiency of this cooperation.

Complicated associations between multiplexed environmental factors and aging are poorly understood. Here, authors show heterogeneous associations of multiplexed environmental factors with multidimensional aging metrics.

Psoriasis is a chronic inflammatory disease affecting up to 3% of the population. Here, Zuo et al.perform exome array analysis, identify single-nucleotide polymorphisms at 15 new loci, implicating several biological pathways in psoriasis risk and disease heritability.

Applications of van der Waals magnetic systems are typically hampered by the low Curie temperature of van der Waals magnets. Here, Wang et al use molecular beam epitaxy to grow large films of Fe₄GeTe₂ with Curie temperatures over 500 K, and the film’s magnetic anisotropy can be tuned arbitrarily by controlling stoichiometry.

Designing efficient and scalable quantum dot LEDs meeting industrial requirements remains a challenge. Here, the authors, by leveraging the liquid phase exchange of d-MX₂ ligands, present printed quantum dot LEDs with external quantum efficiency over 16% and half lifetime of more than 1,721,000 hours.

The surface localized charges in colloidal quantum dots induce a degradation that limits the electroluminescence performance. Here, Chen et al. propose quantum dots with monmonotonically-graded core/shell/shell structures to boost the device’s performance by reducing the surface-bulk coupling.

Colloidal quantum dots are promising for next-generation displays, yet the technology to realise high-resolution and uniform patterning is still scarce. Here, the authors report full-colour QD large area patterning by combining photolithography and selective electrophoretic deposition technique.

Quantum dot light-emitting diodes (QD-LEDs) are attractive for display and lighting applications. Precise understanding of their operational and degradation mechanisms will greatly promote the commercialization of this technology. This Review summarizes the key understanding and remaining challenges of QD-LEDs.

A proteomics study using Guinea Pig ocular posterior pole tissues identifies a novel axis composed of cochlin in the retina, SFRP1 in the RPE, and CaMKII in choroidal vascular endothelial cells responsible for non-pathologic myopia.