Owing to their ultrasmall size effect, nanoparticles (NPs) have been extensively researched in biomedicine for potential applications. They can frequently interact with cells in vivo, forming a series of nano-bio interfaces. The resulting nano-bio interfaces play an important role in dominating the physiological effects of NPs. This review will summarize the progress in nano-bio interface interactions based on theoretical models and simulations. The expected goal of this review is to determine how the properties of NPs affect their interaction with cell membranes, to guide the rational de novo design of NPs, and expand their potential biomedical applications.
- Xiao Zhang
- Guanghui Ma
- Wei Wei
