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Showing 1–50 of 66 results

Advanced filters: Author: Wenjuan Mo Clear advanced filters

A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution

A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promises to be a versatile brainsmatics tool for studying the whole brain at single-cell level.

Zhao Feng
Xiangning Li
Qingming Luo
ResearchOpen Access02 Jul 2025
Nature

P: 1-9
Direct conversion of methane to aromatics and hydrogen via a heterogeneous trimetallic synergistic catalyst

Converting methane to hydrogen and aromatics is a route to upgrading natural gas into high value products. Here the authors report a high-performing synergistic trimetallic thermochemical catalyst, along with mechanistic insights into the process.

Pengxi Zhu
Wenjuan Bian
Hanping Ding
ResearchOpen Access16 Apr 2024
Nature Communications

Volume: 15, P: 1-11
Sintering protonic zirconate cells with enhanced electrolysis stability and Faradaic efficiency

Emerging applications of steam electrolysis and electrochemical synthesis for future hydrogen technologies at intermediate temperatures set stringent requirements on the stability of protonic ceramic cells. Now a sintering approach enables densified Ce-free protonic zirconate cells with enhanced Faradaic efficiency and exceptional stability under harsh operating conditions.

Wei Tang
Wenjuan Bian
Dong Ding
Research14 Mar 2025
Nature Synthesis

Volume: 4, P: 592-602
Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling

Currently, intestinal ischemia/reperfusion injury lacks ideal diagnostic markers and effective therapeutic targets. Here, the authors show exosomal circEZH2_005 is an intestinal injury biomarker and protects the intestine from ischemia/reperfusion injury by promoting crypt cell proliferation via affecting hnRNPA1- mediated Gprc5a stability.

Wenjuan Zhang
Bowei Zhou
Ke-Xuan Liu
ResearchOpen Access06 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Common variants in KCNK5 and FHL5 genes contributed to the susceptibility of migraine without aura in Han Chinese population

Zhao Jiang
Longrui Zhao
Tao Li
ResearchOpen Access24 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Aluminum scandium nitride thin-film bulk acoustic resonators for 5G wideband applications

Yang Zou
Chao Gao
Chengliang Sun
ResearchOpen Access29 Nov 2022
Microsystems & Nanoengineering

Volume: 8, P: 1-7
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

The pathomechanism of succinyl-CoA ligase (SCL) deficiency, a hereditary mitochondrial disease, is not fully understood. Here, the authors show that increased succinyl-CoA levels contribute to SCL pathology by causing global protein hyper-succinylation.

Philipp Gut
Sanna Matilainen
Eric Verdin
ResearchOpen Access23 Nov 2020
Nature Communications

Volume: 11, P: 1-14
Regulation of urea cycle by reversible high-stoichiometry lysine succinylation

Zhang, Fang, et al. develop a method to perform an in-depth lysine succinylation analysis in the mouse liver. This approach allows them to identify a previously unappreciated mechanism of regulation of the urea cycle and ammonia detoxification.

Ran Zhang
Jingqi Fang
Eric Verdin
Research06 Mar 2024
Nature Metabolism

Volume: 6, P: 550-566
Mutation of IPO13 causes recessive ocular coloboma, microphthalmia, and cataract

Xiu-Feng Huang
Lue Xiang
Zi-Bing Jin
ResearchOpen Access27 Apr 2018
Experimental & Molecular Medicine

Volume: 50, P: 1-11
Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus

Systemic lupus erythematosus is characterised by the generation of antibodies targeting DNA and nuclear antigens. Here, the authors show that oxidised mitochondrial DNA induces gasdermin D oligomerization and promotes pore formation in neutrophils from patients with SLE.

Naijun Miao
Zhuning Wang
Jing Wang
ResearchOpen Access16 Feb 2023
Nature Communications

Volume: 14, P: 1-20
Factor Xa cleaves SARS-CoV-2 spike protein to block viral entry and infection

The serine protease factor Xa (FXa) is upregulated in COVID-19 patients and functions in the coagulation pathway. Here, Dong et al characterise the basis of its antiviral activity in the context of SARS-CoV-2 pandemic variants.

Wenjuan Dong
Jing Wang
Jianhua Yu
ResearchOpen Access06 Apr 2023
Nature Communications

Volume: 14, P: 1-18
The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation

Fan Luo
Han Li
Hongyun Zhao
ResearchOpen Access07 Dec 2023
Cellular & Molecular Immunology

Volume: 21, P: 60-79
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP

The development of selective ClpP activators targeting only the MRSA isolates without interfering with the human variant is currently challenging. Here, the authors report on the structure-based design of enantiomers of ZG197 and identify the discriminator factor between the proteins.

Bingyan Wei
Tao Zhang
Cai-Guang Yang
ResearchOpen Access14 Nov 2022
Nature Communications

Volume: 13, P: 1-16
TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca²⁺ leakage

TRPCs, nonselective cation channels, are involved in cardiac contraction and conduction. Here, the authors show that Trpc1/6 deficiency or pharmacological inhibition improves endotoxemic cardiac dysfunction and prolongs survival by prominently suppressing cardiac inflammation and ER Ca²⁺ release.

Na Tang
Wen Tian
Wei Cao
ResearchOpen Access02 Dec 2022
Nature Communications

Volume: 13, P: 1-21
Enhancing recombinant protein production through Cre-loxP mediated chromosomal rearrangement evolution in Kluyveromyces marxianus

Cre-loxP mediated chromosomal rearrangement evolution in Kluyveromyces marxianus can significantly enhance recombinant protein production by cascade activation of cAMP signalling.

Haiyan Ren
Qiyuan Zou
Hong Lu
ResearchOpen Access28 Apr 2025
Communications Biology

Volume: 8, P: 1-14
Integrated network analysis identifies hsa-miR-4756-3p as a regulator of FOXM1 in Triple Negative Breast Cancer

Yuanliang Gu
Wenjuan Wang
Peng Shu
ResearchOpen Access25 Sept 2019
Scientific Reports

Volume: 9, P: 1-8
6 GHz lamb wave acoustic filters based on A1-mode lithium niobate thin film resonators with checker-shaped electrodes

Xin Tong
Yang Zou
Chengliang Sun
ResearchOpen Access19 Sept 2024
Microsystems & Nanoengineering

Volume: 10, P: 1-10
VCAM-1⁺ macrophages guide the homing of HSPCs to a vascular niche

In zebrafish embryogenesis, nascent haematopoietic stem and progenitor cells (HSPCs), homing to a vascular niche for retention, are ushered by patrolling and guiding macrophages through integrin-mediated cell-cell recognition.

Dantong Li
Wenzhi Xue
Weijun Pan
Research19 Nov 2018
Nature

Volume: 564, P: 119-124
PSTPIP2 inhibits cisplatin-induced acute kidney injury by suppressing apoptosis of renal tubular epithelial cells

Hong Zhu
Wenjuan Jiang
Cheng Huang
ResearchOpen Access12 Dec 2020
Cell Death & Disease

Volume: 11, P: 1-13
Ultrasensitive liquid sensor based on an embedded microchannel bulk acoustic wave resonator

Xiyu Gu
Yan Liu
Chengliang Sun
ResearchOpen Access11 Oct 2024
Microsystems & Nanoengineering

Volume: 10, P: 1-10
Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition

Wencao Zhao
Le Cao
Weijun Pan
ResearchOpen Access09 Sept 2019
Cell Research

Volume: 29, P: 895-910
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity

Xiaoli He
Wenjuan Zhang
Lin Li
ResearchOpen Access31 Jan 2017
Cell Discovery

Volume: 3, P: 1-15
Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ

Thiopeptides such as nosiheptide are clinically-interesting antimicrobial natural products. Here the authors show the functional dissection of a series of enzymes involved in nosiheptide biosynthesis, revealing a unique biosynthetic pathway that centers on a previously-unknown carrier protein.

Wei Ding
Wenjuan Ji
Qi Zhang
ResearchOpen Access05 Sept 2017
Nature Communications

Volume: 8, P: 1-7
Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

Xiao-E Jia
Ke Ma
Weijun Pan
ResearchOpen Access03 Jul 2015
Cell Research

Volume: 25, P: 946-962
A PIP₂ substitute mediates voltage sensor-pore coupling in KCNQ activation

Yongfeng Liu, Xianjin Xu, Junyuan Gao et al. perform in silico screening targeting compounds that resemble both KCNQ1 and PIP₂ structures and identify CP1 as a compound that could restore KCNQ1 currents after PIP₂ depletion. Like PIP₂, this compound can mediate VSD-pore coupling of the channel, albeit via a different mechanism from PIP₂.

Yongfeng Liu
Xianjin Xu
Jianmin Cui
ResearchOpen Access16 Jul 2020
Communications Biology

Volume: 3, P: 1-12
The CRL3^BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration

Lihui Li
Wenjuan Zhang
Lijun Jia
ResearchOpen Access24 Apr 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-9
Silencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation

Hongyi Xie
Yuanliang Gu
Peng Shu
ResearchOpen Access21 Jan 2020
Scientific Reports

Volume: 10, P: 1-10
Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells

Yinsong Zhu
Wenjuan He
Hui Chen
ResearchOpen Access04 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Maternal hyperglycemia disturbs neocortical neurogenesis via epigenetic regulation in C57BL/6J mice

Shufang Ji
Wenjuan Zhou
Aijun Hao
ResearchOpen Access01 Mar 2019
Cell Death & Disease

Volume: 10, P: 1-13
Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion

Wenjuan Xian
Michael P Rosenberg
John DiGiovanni
Research27 Mar 1997
Oncogene

Volume: 14, P: 1435-1444
CO₂ enrichment and N addition increase nutrient loss from decomposing leaf litter in subtropical model forest ecosystems

Juxiu Liu
Xiong Fang
Yiyong Li
ResearchOpen Access22 Jan 2015
Scientific Reports

Volume: 5, P: 1-9
PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment

Guangyu Ji
Wenjuan Zhou
Aijun Hao
ResearchOpen Access19 Jun 2021
Cell Death & Disease

Volume: 12, P: 1-12
Reactive oxygen species and aldehyde dehydrogenase activity in Hodgkin lymphoma cells

Jun-ichiro Ikeda
Suhana Mamat
Eiichi Morii
Research20 Feb 2012
Laboratory Investigation

Volume: 92, P: 606-614
mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway

Yiqing Li
Jiaoting Chen
Danian Nie
ResearchOpen Access06 Apr 2020
Cell Death & Disease

Volume: 11, P: 1-12
Dimerization: a structural feature for the protection of hepatitis E virus capsid protein against trypsinization

Wenjuan Wei
Nouredine Behloul
Jihong Meng
ResearchOpen Access29 Jan 2018
Scientific Reports

Volume: 8, P: 1-11
Transistors based on two-dimensional materials for future integrated circuits

This Review examines the development of field-effect transistors based on two-dimensional materials and considers the challenges that need to be addressed for the devices to be incorporated into very large-scale integration (VLSI) technology.

Saptarshi Das
Amritanand Sebastian
Rajendra Singh
Reviews25 Nov 2021
Nature Electronics

Volume: 4, P: 786-799
Pyruvate dehydrogenase kinase 1 protects against neuronal injury and memory loss in mouse models of diabetes

Yuan Yao
Jiaming Shi
Liang Kong
ResearchOpen Access07 Nov 2023
Cell Death & Disease

Volume: 14, P: 1-11
TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness

Renle Du
Wenzhi Shen
Yunping Luo
ResearchOpen Access13 Dec 2019
Signal Transduction and Targeted Therapy

Volume: 4, P: 1-12
Superior plasticity stability and excellent strength in Ti-55531 alloy micropillars via harmony slip in nanoscale α/β phases

Wenjuan Kou
Qiaoyan Sun
Jun Sun
ResearchOpen Access25 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
A medial prefrontal cortex-nucleus acumens corticotropin-releasing factor circuitry for neuropathic pain-increased susceptibility to opioid reward

Yuanzhong Kai
Yanhua Li
Wenjuan Tao
ResearchOpen Access21 May 2018
Translational Psychiatry

Volume: 8, P: 1-12
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth

Wenjuan Li
Kaisa Cui
Youjun Li
ResearchOpen Access30 Apr 2018
Cell Death & Disease

Volume: 9, P: 1-12
MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway

Hongbo Zou
Qian Chen
Chuan Xu
ResearchOpen Access15 Feb 2019
Cell Death & Disease

Volume: 10, P: 1-13
RETRACTED ARTICLE: Norcantharidin combined with Coix seed oil synergistically induces apoptosis and inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation

Dan Wang
Chendong Yang
Qiusheng Zheng
ResearchOpen Access24 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Coupling thermotolerance and high production of recombinant protein by CYR1^N1546K mutation via cAMP signaling cascades

The CYR1 mutation can enhance a strain’s thermotolerance and ability to produce high yields of recombinant protein by simultaneously strengthening stress resistance and the energy system through cAMP signalling cascades.

Haiyan Ren
Qing Lan
Hong Lu
ResearchOpen Access24 May 2024
Communications Biology

Volume: 7, P: 1-14
MiR218 Modulates Wnt Signaling in Mouse Cardiac Stem Cells by Promoting Proliferation and Inhibiting Differentiation through a Positive Feedback Loop

Yongshun Wang
Jingjin Liu
Bo Yu
ResearchOpen Access10 Feb 2016
Scientific Reports

Volume: 6, P: 1-15
A monocarboxylate transporter-dependent mechanism confers resistance to exercise-induced fatigue in a high-altitude hypoxic environment

Chen Gao
Binni Yang
Wenjuan Pei
ResearchOpen Access20 Feb 2023
Scientific Reports

Volume: 13, P: 1-10
Inhibition of cannabinoid receptor type 1 sensitizes triple-negative breast cancer cells to ferroptosis via regulating fatty acid metabolism

Pengyun Li
Qiaohong Lin
Song Li
ResearchOpen Access21 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-15
Mutational Spectrum of Phenylketonuria in the Chinese Han Population: A Novel Insight into the Geographic Distribution of the Common Mutations

Tianwen Zhu
Shengying Qin
Xuefan Gu
Research01 Mar 2010
Pediatric Research

Volume: 67, P: 280-285
C1q/TNF-related protein-9 ameliorates hypoxia-induced pulmonary hypertension by regulating secretion of endothelin-1 and nitric oxide mediated by AMPK in rats

Qiaoyan Jin
Hui Su
Xin Sun
ResearchOpen Access31 May 2021
Scientific Reports

Volume: 11, P: 1-13
High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes

Eugene K. Oteng
Wenjuan Gu
Maureen McKeague
ResearchOpen Access16 Jun 2020
Scientific Reports

Volume: 10, P: 1-11

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