Nature Search

Author Correction: Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA

Fangting Zuo
Li Jiang
Yi Yang
Amendments and Corrections28 Mar 2025
Nature Chemical Biology

Volume: 21, P: 790
Covalently reactive microparticles imbibe blood to form fortified clots for rapid hemostasis and prevention of rebleeding

Hemostatic failure and the risk of rebleeding present significant challenges. Here, Chen et al. design a covalently reactive hemostat based on blood-imbibing and -crosslinking microparticles, achieving rapid hemostasis and preventing rebleeding.

Ting Chen
Chaonan Xiao
Linyong Zhu
ResearchOpen Access18 Apr 2025
Nature Communications

Volume: 16, P: 1-16
Multi-omics analysis of canine aging markers and evaluation of stem cell intervention

Multi-omics analysis of canine aging uncovers aging-related cell populations & markers, identifies Penitrem A & UDP-N-acetylglucosamine as metabolic hallmarks, & demonstrates MSCs overexpressing NMNAT1 can delay or reverse aging in dogs.

Balun Li
Yanheng Ding
Jinlian Hua
ResearchOpen Access10 Jun 2025
Communications Biology

Volume: 8, P: 1-18
Erratum: Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

Rongkun Tao
Yuzheng Zhao
Yi Yang
Amendments and Corrections01 Sept 2017
Nature Methods

Volume: 14, P: 928
A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy

Zhenglin Yang and colleagues use whole-exome sequencing to identify a rare variant in the FGD6 gene that is associated with the polypoidal choroidal vasculopathy subtype of wet age-related macular degeneration. They show that FGD6 regulates proangiogenic effects together with VEGF and that the mutation results in abnormal retinal vessel development.

Lulin Huang
Houbin Zhang
Zhenglin Yang
Research18 Apr 2016
Nature Genetics

Volume: 48, P: 640-647
ImmuneApp for HLA-I epitope prediction and immunopeptidome analysis

The identification of HLA epitopes is essential for vaccine and immunotherapy development. Here, authors develop ImmuneApp using deep learning on extensive immunopeptidomics data, advancing antigen presentation prediction, neoepitope prioritisation, and immunopeptidomics deconvolution.

Haodong Xu
Ruifeng Hu
Zhongming Zhao
ResearchOpen Access16 Oct 2024
Nature Communications

Volume: 15, P: 1-15
Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells

The Clivias are a series of small, monomeric fluorescent RNAs that emit with a large Stokes shift in the orange–red. They enable multiplexed RNA imaging in live cells and BRET-based detection of protein–RNA interactions in mice.

Li Jiang
Xin Xie
Yi Yang
Research18 Sept 2023
Nature Methods

Volume: 20, P: 1563-1572
A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice

Pulsing cellular dynamics in genetic circuits have been shown to provide critical capabilities to cells in diverse cellular activities. Here the authors show a synthetic BRET-based transgene expression system that allows pulsatile and quantitative activation of gene expression both in live cells and in vivo.

Ting Li
Xianjun Chen
Yi Yang
ResearchOpen Access27 Jan 2021
Nature Communications

Volume: 12, P: 1-10
Haplotype-resolved gapless genome and chromosome segment substitution lines facilitate gene identification in wild rice

Genetic variation present in wild rice is a reservoir of useful genes for rice breeding. Here, the authors report the haplotype-resolved gapless genome assembly of wild rice, the development of two sets of chromosome segment substitution lines, and the cloning of a blast resistance gene originated from wild rice.

Jingfen Huang
Yilin Zhang
Weihua Qiao
ResearchOpen Access29 May 2024
Nature Communications

Volume: 15, P: 1-15
Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA

Zuo et al. developed a highly bright and stable green fluorescent RNA for robust imaging of the dynamics of messenger RNA in living cells, enabling visualization of nonuniform and distinct distributions of different RNAs throughout stress granules.

Fangting Zuo
Li Jiang
Yi Yang
Research23 May 2024
Nature Chemical Biology

Volume: 20, P: 1272-1281
Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins

Photoswitchable RNA-binding proteins enable the spatiotemporal control of RNA function.

Renmei Liu
Jing Yang
Yi Yang
Research03 Jan 2022
Nature Biotechnology

Volume: 40, P: 779-786
Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

Genetically encoded iNap sensors allow imaging of NADPH with high spatiotemporal resolution in living systems. The iNaps cover physiologically relevant NADPH concentrations and are demonstrated in mammalian cells and live zebrafish.

Rongkun Tao
Yuzheng Zhao
Yi Yang
Research05 Jun 2017
Nature Methods

Volume: 14, P: 720-728
CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Qun Zhao
Jingyi Wu
Xianjun Yu
ResearchOpen Access05 May 2025
Cell Death & Disease

Volume: 16, P: 1-15
Crystal structure of a multi-___domain human smoothened receptor in complex with a super stabilizing ligand

Smoothened receptors (SMO) play a key role in the Hedgehog signalling pathway. Here the authors present the structure of a multi-___domain human SMO with a rationally designed stabilizing ligand bound in the transmembrane ___domain of the receptor, and propose a model for SMO activation.

Xianjun Zhang
Fei Zhao
Fei Xu
ResearchOpen Access17 May 2017
Nature Communications

Volume: 8, P: 1-10
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease

Dopamine neurons control movements while pyramidal neurons regulate memory and language. Here the authors show that circular RNAs production in these neurons appears tailored to neuron identity and genetically linked to neuropsychiatric disease such as Parkinson’s and Alzheimer’s disease.

Xianjun Dong
Yunfei Bai
Clemens R. Scherzer
ResearchOpen Access18 Sept 2023
Nature Communications

Volume: 14, P: 1-12
A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi

Hsp110 chaperones play important roles in protein homeostasis in eukaryotes. Here, the authors identify a small compound that inhibits fungal Hsp110s as well as the growth and viability of the pathogenic fungus Candida albicans, supporting Hsp110s as targets for development of new antifungal drugs.

Liqing Hu
Cancan Sun
Qinglian Liu
ResearchOpen Access12 May 2023
Nature Communications

Volume: 14, P: 1-16
Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs

A series of bright fluorescent RNAs with a broad emission spectra enable live cell imaging of RNA dynamics.

Xianjun Chen
Dasheng Zhang
Yi Yang
Research23 Sept 2019
Nature Biotechnology

Volume: 37, P: 1287-1293
Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy

Lin Zhang
Xiang Zhang
Zhenglin Yang
Research05 Jul 2019
Genetics in Medicine

Volume: 22, P: 77-84
Elucidating key factors in regulating budgets of ozone and its precursors in atmospheric boundary layer

Xin Song
Xiao-Bing Li
Min Shao
ResearchOpen Access28 Oct 2024
npj Climate and Atmospheric Science

Volume: 7, P: 1-15
Identification and functional analysis of novel FZD4 mutations in Han Chinese with familial exudative vitreoretinopathy

Ping Fei
Xiong Zhu
Xianjun Zhu
ResearchOpen Access04 Nov 2015
Scientific Reports

Volume: 5, P: 1-6
Nitrogen use aggravates bacterial diversity and network complexity responses to temperature

Xiaoyi Xing
Huifang Xu
Baoli Zhu
ResearchOpen Access17 Aug 2022
Scientific Reports

Volume: 12, P: 1-10
A genetically encoded toolkit for tracking live-cell histidine dynamics in space and time

Hanyang Hu
Yanfang Gu
Yi Yang
ResearchOpen Access02 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Publisher Correction: A functional variant in the OAS1 gene is associated with Sjögren’s syndrome complicated with HBV infection

Xianjun Liu
Hongcun Xing
Shaofeng Wang
Amendments and CorrectionsOpen Access14 Nov 2018
Scientific Reports

Volume: 8, P: 1
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

Dongxin Lin and colleagues report a genome-wide association study for pancreatic cancer in Chinese populations. The authors identify five new genetic loci associated with risk of pancreatic cancer.

Chen Wu
Xiaoping Miao
Dongxin Lin
Research11 Dec 2011
Nature Genetics

Volume: 44, P: 62-66
Pirfenidone alleviates fibrosis by acting on tumour–stroma interplay in pancreatic cancer

Yalan Lei
Jin Xu
Si Shi
Research07 Mar 2024
British Journal of Cancer

Volume: 130, P: 1505-1516
Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors

This protocol describes how to combine up to four genetically encoded fluorescent sensors to image redox landscapes. The procedure describes applications in live imaging and flow cytometry of cultured cells, and in vivo imaging in zebrafish larvae.

Yejun Zou
Aoxue Wang
Yuzheng Zhao
Protocols26 Sept 2018
Nature Protocols

Volume: 13, P: 2362-2386
Functional significance of cholesterol metabolism in cancer: from threat to treatment

Mingming Xiao
Jin Xu
Si Shi
ReviewsOpen Access01 Sept 2023
Experimental & Molecular Medicine

Volume: 55, P: 1982-1995
MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy

Xianjun Yu
Mengyuan Feng
Qun Zhao
Research23 May 2024
Cell Death & Differentiation

Volume: 31, P: 1085-1098
Spatiotemporal control of gene expression by a light-switchable transgene system

A light-inducible dimerization ___domain is used to create a genetically encoded, light-switchable transactivator of gene expression. The system allows rapid blue light–mediated activation of transgenes containing an appropriate activation sequence with low background and high induction.

Xue Wang
Xianjun Chen
Yi Yang
Research12 Feb 2012
Nature Methods

Volume: 9, P: 266-269
Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

Zhenglin Yang, Xinghuai Sun and colleagues report the results of a genome-wide association study of primary open-angle glaucoma in East Asians. They show that common variants near ABCA1 and in PPM2 are associated with increased risk of this disease.

Yuhong Chen
Ying Lin
Zhenglin Yang
Research31 Aug 2014
Nature Genetics

Volume: 46, P: 1115-1119
A functional variant in the OAS1 gene is associated with Sjögren’s syndrome complicated with HBV infection

Xianjun Liu
Hongcun Xing
Shaofeng Wang
ResearchOpen Access14 Dec 2017
Scientific Reports

Volume: 7, P: 1-9
Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters

Dasheng Zhang
Zhengda Chen
Linyong Zhu
ResearchOpen Access13 Jun 2023
Cell Discovery

Volume: 9, P: 1-17
Pristimerin induces apoptosis and autophagy via activation of ROS/ASK1/JNK pathway in human breast cancer in vitro and in vivo

Qun Zhao
Yingxiang Liu
Xianjun Yu
ResearchOpen Access05 Aug 2019
Cell Death Discovery

Volume: 5, P: 1-13
Transcriptome and genome sequencing elucidates the molecular basis for the high yield and good quality of the hybrid rice variety Chuanyou6203

Juansheng Ren
Fan Zhang
Guangjun Ren
ResearchOpen Access17 Nov 2020
Scientific Reports

Volume: 10, P: 1-15
Epigenetic regulation in the tumor microenvironment: molecular mechanisms and therapeutic targets

Jing Yang
Jin Xu
Si Shi
ReviewsOpen Access22 May 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-26
RIP1 kinase activity-dependent roles in embryonic development of Fadd-deficient mice

Yongbo Liu
Cunxian Fan
Haibing Zhang
Research02 Jun 2017
Cell Death & Differentiation

Volume: 24, P: 1459-1469
Liquid–liquid phase separation in tumor biology

Xuhui Tong
Rong Tang
Si Shi
ReviewsOpen Access08 Jul 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-22
Novel schizophrenia risk factor pathways regulate FEZ1 to advance oligodendroglia development

Xianjun Chen
Li Ku
Yue Feng
ReviewsOpen Access18 Dec 2017
Translational Psychiatry

Volume: 7, P: 1-10

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