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Scientific Reports (35)
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Showing 1–50 of 76 results

Advanced filters: Author: Xiao-Li You Clear advanced filters

Plasmonic in-situ imaging of zeta potential distributions at electrochemical interfaces of 2D materials in water

Understanding the electrical double layer at solid-liquid interfaces is crucial for various technologies. Here, the authors present an optical method for direct visualization and quantification of the zeta potential at 2D material interfaces.

Xiaona Zhao
Xiao-Li Zhou
Xian-Wei Liu
ResearchOpen Access12 Apr 2025
Nature Communications

Volume: 16, P: 1-8
Self-assembly, interlocking, interconversion and anion-binding catalysis in phenoxazine-based Pd₂L₄ and Pd₄L₈ coordination cages

While Pd₂L₄-type coordination cages tend to form interlocked dimers, isolation and characterization of both the cage and its interlocked dimer is very challenging. Herein, the authors report the synthesis and solvent-mediated interconversion of highly soluble phenoxazine-based monomeric cage and corresponding interlocked dimer.

Qiong-Yan Hong
Bin Huang
Xueliang Shi
ResearchOpen Access13 Mar 2025
Nature Communications

Volume: 16, P: 1-13
ZD7288 ameliorates long-term cerebral ischemia reperfusion-induced deterioration of spatial memory by regulating the expressions of NMDA receptor subunits in rats

Zhi He
Xiao-Jiao Chu
Bo Zhao
ResearchOpen Access25 May 2025
Scientific Reports

Volume: 15, P: 1-13
The introduction of the Barbier reaction into polymer chemistry

The Barbier reaction, a widely utilized reaction for carbon–carbon bond formation, has played important roles in modern organic chemistry. Here, the authors show a one-pot Barbier polyaddition reaction of monomers containing an organic halide and a benzoyl group to form a series of phenylmethanol group containing polymers.

Xiao-Li Sun
Dong-Ming Liu
Wen-Ming Wan
ResearchOpen Access31 Oct 2017
Nature Communications

Volume: 8, P: 1-7
N, N’-bidentate ligand anchored palladium catalysts on MOFs for efficient Heck reaction

Metal-organic frameworks have earned attention for their potential to address the longevity of catalytic centers. Here, the authors have synthesized an amino-pyridine benzoic acid ligand to disperse palladium catalytic centers atomically resulting in a high average turnover number (95000) and low metal residue (4.8 ppm) in the Heck reaction.

Xiao-Li Xu
Nian-Nian Wang
Yi Lu
ResearchOpen Access23 Aug 2024
Nature Communications

Volume: 15, P: 1-10
Unrepresentative big surveys significantly overestimated US vaccine uptake

An analysis of three surveys of COVID-19 vaccine behaviour shows that larger surveys overconfidently overestimated vaccine uptake, a demonstration of how larger sample sizes can paradoxically lead to less accurate estimates.

Valerie C. Bradley
Shiro Kuriwaki
Seth Flaxman
Research08 Dec 2021
Nature

Volume: 600, P: 695-700
Upcycled high-strength aluminum alloys from scrap through solid-phase alloying

The authors propose a scalable solid phase process to upcycle aluminum scrap into a high-strength alloy with 200% strength improvement. The process reduces energy consumption and carbon emissions while making customizable materials from waste by tailoring the chemical composition.

Tianhao Wang
Xiao Li
Jorge F. dos Santos
ResearchOpen Access10 Dec 2024
Nature Communications

Volume: 15, P: 1-8
Cardiomyocyte specific CD38 deletion protects heart from acute myocardial infarction by activating Sirt3 signaling pathway

Ke Wen
Ya-Ting Zhang
Hong-Bo Xin
ResearchOpen Access17 May 2025
Scientific Reports

Volume: 15, P: 1-12
First-in-human phase Ia study of the PI3Kα inhibitor CYH33 in patients with solid tumors

PIK3CA is a commonly mutated cancer-associated gene, making it an attractive therapeutic target. Here, the authors report the results of a first-in-human phase Ia trial to assess the safety and recommended phase II dose of CYH33, a PI3Kα inhibitor, in patients with advanced solid tumors.

Xiao-Li Wei
Fu-Rong Liu
Rui-Hua Xu
ResearchOpen Access16 Nov 2022
Nature Communications

Volume: 13, P: 1-10
The association between triglyceride glucose-body mass index and mortality in critically ill patients with respiratory failure: insights from ICU data

Ce Sun
Xiao-Li Niu
Li-Xiong Zeng
ResearchOpen Access09 May 2025
Scientific Reports

Volume: 15, P: 1-13
A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis

Here, the authors report the results of a randomized, placebo controlled trial of children with acute gastroenteritis who were treated with a probiotic and find no virus-specific beneficial effects attributable to the probiotic, either in reducing clinical symptoms or clearance of viral nucleic acid from stool specimens.

Stephen B. Freedman
Jianling Xie
Marc H. Gorelick
ResearchOpen Access21 May 2020
Nature Communications

Volume: 11, P: 1-9
Comprehensive analysis of risk factors for flap necrosis in free flap reconstruction of postoperative tissue defects in oral and maxillofacial tumors

Shao-bo Ouyang
Zhi-hong Wu
Xiao-li Lu
ResearchOpen Access12 Aug 2024
Scientific Reports

Volume: 14, P: 1-6
Single-gold etching at the hypercarbon atom of C-centred hexagold(I) clusters protected by chiral N-heterocyclic carbenes

The control of atomically precise etching of nano-sized metal clusters is important for understanding their structure-specific properties. Here, the authors report the etching of a single gold atom on a hypercarbon centre of gold(I) clusters.

Xiao-Li Pei
Pei Zhao
Mitsuhiko Shionoya
ResearchOpen Access12 Jun 2024
Nature Communications

Volume: 15, P: 1-10
Addendum: TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

Guoliang Lyu
Yiting Guan
Wei Tao
Amendments and CorrectionsOpen Access08 Oct 2018
Nature Communications

Volume: 9, P: 1
N-Heterocyclic carbene-based C-centered Au(I)-Ag(I) clusters with intense phosphorescence and organelle-selective translocation in cells

Photoluminescent gold clusters have unique chemical and physical properties based on their perturbed electronic structures. Here, the authors report the synthesis of carbon-centered Au(I)-Ag(I) clusters with high phosphorescence quantum yields using N-heterocyclic carbene ligands.

Zhen Lei
Mizuki Endo
Mitsuhiko Shionoya
ResearchOpen Access10 Aug 2022
Nature Communications

Volume: 13, P: 1-9
Identification of an angiogenic factor that when mutated causes susceptibility to Klippel–Trenaunay syndrome

Xiao-Li Tian
Rajkumar Kadaba
Qing Wang
Research12 Feb 2004
Nature

Volume: 427, P: 640-645
Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition

The molecular and cellular mechanisms of cortical disinhibition as a common feature of many psychiatric diseases are not fully understood. The authors identify an interaction between NRG1 and Nav1.1 sodium channel as a mechanism of how NRG1 modulates the excitability of GABAergic interneurons.

Yao-Yi Wang
Bing Zhao
Dong-Min Yin
ResearchOpen Access12 Jan 2021
Nature Communications

Volume: 12, P: 1-13
Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection

Understanding if lasting immune responses can be induced by SARS-CoV-2 infection is important for controlling the COVID-19 pandemic. Here, the authors show, in a cohort of 25 patients, that IgG and T cell responses, as well as neutralising antibody, are still detectable against various SARS-CoV-2 proteins 3 months post-symptom onset, while IgM levels largely wane at this time.

Xiao-Lin Jiang
Guo-Lin Wang
Mai-Juan Ma
ResearchOpen Access09 Feb 2021
Nature Communications

Volume: 12, P: 1-10
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase

Understanding how membrane-bound styrene oxide isomerase (SOI) catalyses the Meinwald rearrangement—a Lewis-acid-catalysed isomerization of an epoxide to a carbonyl compound—can be useful as SOI represents a green alternative to chemical synthesis. Here, the catalytic mechanism of SOI was determined using cryo-EM, EPR spectroscopy, mutagenesis, functional assays and docking experiments.

Basavraj Khanppnavar
Joel P. S. Choo
Xiaodan Li
ResearchOpen Access14 May 2024
Nature Chemistry

Volume: 16, P: 1496-1504
Analysis of age-specified and genotype distribution of HPV multiple infections in the Chinese population

Yu-Xia Zhou
Xiao-Hui Ma
Xiao-Qian Zhang
ResearchOpen Access01 Feb 2024
Scientific Reports

Volume: 14, P: 1-9
Plasmonic imaging of the layer-dependent electrocatalytic activity of two-dimensional catalysts

Probing the localized electrocatalytic activity of heterogeneous electrocatalysts is crucial. Here, the authors propose a method of imaging the surface charge density and electrocatalytic activity of single two-dimensional electrocatalyst nanosheets.

Xiaona Zhao
Xiao-Li Zhou
Xian-Wei Liu
ResearchOpen Access22 Dec 2022
Nature Communications

Volume: 13, P: 1-8
Transcriptome analysis reveals the expression of genes involved in the formation of petal variegation in Impatiens morsei

Hai-Ge Liu
Ting-Ting Feng
Hai-Quan Huang
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
Highly efficient synthesis of non-planar macrocycles possessing intriguing self-assembling behaviors and ethene/ethyne capture properties

The design of covalent macrocycles which show characteristic self-assembly behaviour and host-guest properties is challenging. Here, the authors demonstrate the synthesis of diphenylamine[n]arenes through a one-pot synthesis and demonstrate the π-π pi stacking of the non-planar rings as well as ethane/ethyne host-guest interactions.

Lijun Mao
Yang Hu
Xueliang Shi
ResearchOpen Access16 Nov 2020
Nature Communications

Volume: 11, P: 1-10
Efficient self-assembly of heterometallic triangular necklace with strong antibacterial activity

Precise assembly of heterometallic complexes is a challenge. Here, the authors design a heterometallic triangular necklace through a highly efficient threading-and-ring-closing approach driven by metal-ligand coordination, which shows strong bacterium-binding and cell wall/plasma membrane-disrupting capacity for killing bacterial cells.

Gui-Yuan Wu
Xueliang Shi
Hai-Bo Yang
ResearchOpen Access23 Jun 2020
Nature Communications

Volume: 11, P: 1-11
TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

Cellular senescence is associated with epigenetic remodeling. Here, the authors report that TGF-β signaling promotes miR-29 mediated loss of H4K20me3 thus accelerating senescence.

Guoliang Lyu
Yiting Guan
Wei Tao
ResearchOpen Access02 Jul 2018
Nature Communications

Volume: 9, P: 1-13
Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones

Chiral spirocyclic compounds are important structural motifs for drug discovery. Here, the authors report a synthetic route to spirocycles based on enantioselective cycloaddition of activated spirocyclopropyl oxindoles, which act as donor-acceptor cyclopropanes.

Peng-Wei Xu
Jia-Kuan Liu
Jian Zhou
ResearchOpen Access20 Nov 2017
Nature Communications

Volume: 8, P: 1-8
Switchable organoplatinum metallacycles with high quantum yields and tunable fluorescence wavelengths

Fluorescent supramolecular coordination complexes are of interest for chemical sensing and optical devices. Here the authors synthesize nine organoplatinum metallacycles with high quantum yields, whose fluorescence wavelengths are tuned through manipulation of their photoinduced electron transfer and intramolecular charge transfer properties.

Jun-Long Zhu
Lin Xu
Hai-Bo Yang
ResearchOpen Access19 Sept 2019
Nature Communications

Volume: 10, P: 1-12
Effects of different concentrations of intraluminal sodium chloride solution on intracavitary ECG used for arm infusion port implantation

Lei Dong
Chen-yang Guan
Qi Zhang
ResearchOpen Access15 Aug 2022
Scientific Reports

Volume: 12, P: 1-6
Dual effect of erbB-2 depletion on the regulation of DNA repair and cell cycle mechanisms in non-small cell lung cancer cells

Xiao-Li You
Lily Yen
Moulay A Alaoui-Jamali
Research17 Dec 1998
Oncogene

Volume: 17, P: 3177-3186
Developing a nomogram for risk prediction of the low T3 syndrome

Xiao-Li Feng
Hui-Min Chen
Li-Liang Chen
ResearchOpen Access10 Feb 2025
Scientific Reports

Volume: 15, P: 1-10
An integrated multi-omics analysis identifies protein biomarkers and potential drug targets for psoriatic arthritis

This study employed proteome-wide mendelian randomization to identify seven plasma proteins associated with PsA, offering potential insights for personalized PsA treatment strategies

Yi-Xin Cai
Dai-Shan Zheng
Xiu-Feng Huang
ResearchOpen Access14 Feb 2025
Communications Biology

Volume: 8, P: 1-9
The Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT

Fang-ming Chen
Yun-xiang Zhang
Ming-chen Wang
ResearchOpen Access16 Jun 2020
Scientific Reports

Volume: 10, P: 1-9
Celecoxib alleviates nonalcoholic fatty liver disease by restoring autophagic flux

Cong Liu
Lian Liu
Pei-Yuan Li
ResearchOpen Access07 Mar 2018
Scientific Reports

Volume: 8, P: 1-10
Synthesis and conformational analysis of linear homo- and heterooligomers from novel 2-C-branched sugar amino acids (SAAs)

Guang-Zong Tian
Jing Hu
Jian Yin
ResearchOpen Access26 Apr 2018
Scientific Reports

Volume: 8, P: 1-8
NAA at a high concentration promotes efficient plant regeneration via direct somatic embryogenesis and SE-mediated transformation system in Ranunculus sceleratus

Ke-dong Xu
Wei Wang
Cheng-wei Li
ResearchOpen Access04 Dec 2019
Scientific Reports

Volume: 9, P: 1-8
Three novel obese indicators perform better in monitoring management of metabolic syndrome in type 2 diabetes

Chun-Ming Ma
Na Lu
Fu-Zai Yin
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-6
Hyperuricemia is associated with cardiovascular diseases clustering among very elderly women - a community based study in Chengdu, China

Gang Huang
Jun-bo Xu
Bao-yu Zhao
ResearchOpen Access20 Apr 2017
Scientific Reports

Volume: 7, P: 1-8
Perioperative statin administration with decreased risk of postoperative atrial fibrillation, but not acute kidney injury or myocardial infarction: A meta-analysis

Li Zhen-Han
Shi Rui
Feng Bo
ResearchOpen Access30 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Deciphering cell to cell spatial relationship for pathology images using SpatialQPFs

Xiao Li
ResearchOpen Access28 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Comprehensive immunogenomic landscape analysis of prognosis-related genes in head and neck cancer

Lei Li
Xiao-Li Wang
Yong-Wen He
ResearchOpen Access14 Apr 2020
Scientific Reports

Volume: 10, P: 1-27
Regulation of cellular response to cisplatin-induced DNA damage and DNA repair in cells overexpressing p185^erbB-2 is dependent on the ras signaling pathway

Lily Yen
Nie Zeng-Rong
Moulay A Alaoui-Jamali
Research17 Apr 1997
Oncogene

Volume: 14, P: 1827-1835
Network pharmacology to explore the mechanism of scutellarin in the treatment of brain ischaemia and experimental verification of JAK2/STAT3 signalling pathway

Qiu-Ye Jia
Hao‑Lun Chen
Chun‑Yun Wu
ResearchOpen Access09 May 2023
Scientific Reports

Volume: 13, P: 1-11
NOTCH3 as a prognostic biomarker and its correlation with immune infiltration in gastrointestinal cancers

Jia Xu
Xiao-li Jin
Jian Xu
ResearchOpen Access21 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
Effect and mechanism of human umbilical cord mesenchymal stem cells in treating allergic rhinitis in mice

Xiao-li Kan
Xing-hua Pan
Guang-ping Ruan
ResearchOpen Access09 Nov 2020
Scientific Reports

Volume: 10, P: 1-19
A two-microRNA-based signature predicts first-line chemotherapy outcomes in advanced colorectal cancer patients

Jia-huan Lu
Zhi-xiang Zuo
Zhao-lei Zeng
ResearchOpen Access18 Dec 2018
Cell Death Discovery

Volume: 4, P: 1-12
TRIB1 and TRPS1 variants, G × G and G × E interactions on serum lipid levels, the risk of coronary heart disease and ischemic stroke

Qing-Hui Zhang
Rui-Xing Yin
Jin-Zhen Wu
ResearchOpen Access20 Feb 2019
Scientific Reports

Volume: 9, P: 1-13
Utilization of a Wheat660K SNP array-derived high-density genetic map for high-resolution mapping of a major QTL for kernel number

Fa Cui
Na Zhang
Jun-ming Li
ResearchOpen Access19 Jun 2017
Scientific Reports

Volume: 7, P: 1-12
Diversity of Trichoderma species associated with soil in the Zoige alpine wetland of Southwest China

Gui-Ting Tang
Ying Li
Guo-Shu Gong
ResearchOpen Access15 Dec 2022
Scientific Reports

Volume: 12, P: 1-22
A variant-proof SARS-CoV-2 vaccine targeting HR1 ___domain in S2 subunit of spike protein

Wei Pang
Ying Lu
Yong-Tang Zheng
ResearchOpen Access10 Nov 2022
Cell Research

Volume: 32, P: 1068-1085
Long-term outcome of children with acute promyelocytic leukemia: a randomized study of oral versus intravenous arsenic by SCCLG-APL group

Dan-Ping Huang
Liang-Chun Yang
Li-Bin Huang
ResearchOpen Access05 Dec 2023
Blood Cancer Journal

Volume: 13, P: 1-7

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