Nature Search

Reference intervals for coagulation parameters in chinese adults stratified by sex and age

Xin-Xing Lei
Shao-Rong Qiu
Yin-Jing Xie
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Structures of the ADGRG2–G_s complex in apo and ligand-bound forms

The description of the cryo-EM structure of an orphan adhesion GPCR–G_s protein complex in apo state facilitates the screening and identification of potential ligands of ADGRG2.

Hui Lin
Peng Xiao
Xiao Yu
Research18 Aug 2022
Nature Chemical Biology

Volume: 18, P: 1196-1203
Machine Learning Algorithms for Risk Prediction of Severe Hand-Foot-Mouth Disease in Children

Bin Zhang
Xiang Wan
Shui-xing Zhang
ResearchOpen Access14 Jul 2017
Scientific Reports

Volume: 7, P: 1-8
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

Tumour-associated macrophages (TAMs) facilitate malignant growth of glioblastoma (GBM). Here, the authors show that TAMs support glioma stem cell renewal via paracrine signalling to the pleiotrophin receptor PTPRZ1 and that blocking this axis results in increased survival of tumour-bearing animals.

Yu Shi
Yi-Fang Ping
Xiu-Wu Bian
ResearchOpen Access01 Jun 2017
Nature Communications

Volume: 8, P: 1-17
A nomogram for predicting T315I-free survival in chronic phase chronic myeloid leukemia patients: a multicenter retrospective study

Shi-wei Hu
Xiu-di Yang
Jian Huang
ResearchOpen Access18 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells

The authors demonstrate that carnitine palmitoyltransferase 1A (CPT1A) expression is reduced in glioma stem cells (GSCs) in comparison with non-stem tumor cells. CPT1A overexpression promotes mitochondrial fusion and GSC differentiation by increasing the phosphorylation of dynamin-related protein 1 (Drp1) at Ser-637, thus impairing GSC-derived xenograft growth and prolonging survival in tumor-bearing mice. These results suggest that CPT1A could be a molecular target for GSC differentiation therapy.

Min Luo
Yu-Qi Liu
Yi-Fang Ping
Research28 Dec 2021
Laboratory Investigation

Volume: 102, P: 722-730
Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex

Xuan Qin
Yang Yang
Yuan Huang
Research07 Dec 2009
Acta Pharmacologica Sinica

Volume: 31, P: 127-136
Strategies for an HIV cure: progress and challenges

The ‘Strategies for an HIV Cure’ conference was held 27–28 April 2018 in Beijing, China, and was hosted by The People's Republic of China Ministry of Science and Technology and the Chinese Academy of Sciences.

Fu Sheng Wang
Linqi Zhang
Sharon R. Lewin
News & Views17 Oct 2018
Nature Immunology

Volume: 19, P: 1155-1158
Neuropeptide Initiated Mast Cell Activation by Transcutaneous Electrical Acupoint Stimulation of Acupoint LI4 in Rats

Li-Zhen Chen
Yu Kan
Xiang-Hong Jing
ResearchOpen Access17 Sept 2018
Scientific Reports

Volume: 8, P: 1-12
Pulse Wave Velocity as a Marker of Arteriosclerosis and Its Comorbidities in Chinese Patients

Xiao-Ning Liu
Hai-Qing Gao
Min Wang
Research01 Mar 2007
Hypertension Research

Volume: 30, P: 237-242
Non-equilibrium synergistic effects in atmospheric pressure plasmas

Heng Guo
Xiao-Ning Zhang
Kostya (Ken) Ostrikov
ResearchOpen Access19 Mar 2018
Scientific Reports

Volume: 8, P: 1-10
SLC38A4 functions as a tumour suppressor in hepatocellular carcinoma through modulating Wnt/β-catenin/MYC/HMGCS2 axis

Jie Li
Ming-han Li
Ji-hang Yuan
Research17 Jul 2021
British Journal of Cancer

Volume: 125, P: 865-876
Dicer deficiency impairs proliferation but potentiates anti-tumoral effect of macrophages in glioblastoma

Yu-Qi Liu
Min Luo
Yi-Fang Ping
Research28 Jun 2022
Oncogene

Volume: 41, P: 3791-3803
Identification of pimavanserin tartrate as a potent Ca²⁺-calcineurin-NFAT pathway inhibitor for glioblastoma therapy

Zhen-zhen Liu
Xiao-ning Liu
Bo Tang
Research06 Aug 2021
Acta Pharmacologica Sinica

Volume: 42, P: 1860-1874
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs

Xiao-kang Zhao
Meng-meng Zhu
Yuan-li Chen
Research30 Mar 2023
Acta Pharmacologica Sinica

Volume: 44, P: 1625-1636
Erythromycin suppresses neutrophil extracellular traps in smoking-related chronic pulmonary inflammation

Hui Zhang
Shi-Lin Qiu
Xiao-Ning Zhong
ResearchOpen Access12 Sept 2019
Cell Death & Disease

Volume: 10, P: 1-15
Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium

Jie Wang
Mei Bai
Qiang Xu
Research14 Aug 2023
Acta Pharmacologica Sinica

Volume: 44, P: 2469-2478
VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

Kai Zhou
Yue-Liang Yao
Yi-Fang Ping
ResearchOpen Access24 Sept 2018
Cell Death & Disease

Volume: 9, P: 1-14
Ovarian cancer treatment with a tumor-targeting and gene expression-controllable lipoplex

Zhi-Yao He
Feng Deng
Yu-Quan Wei
ResearchOpen Access30 Mar 2016
Scientific Reports

Volume: 6, P: 1-13
High levels of TIMP1 are associated with increased extracellular matrix stiffness in isocitrate dehydrogenase 1-wild type gliomas

The authors identified tissue inhibitor of metalloproteinase-1 (TIMP1) as an important regulator of tissue stiffness in isocitrate dehydrogenase (IDH)-wild type (WT) gliomas. TIMP1 knockdown decreases tissue stiffness, inhibited the expression of tenascin C and fibronectin, and suppressed tumor progression. These results suggest that TIMP1 could be a potential therapeutic target for IDH-WT gliomas.

Chun-Hua Luo
Yu Shi
Yi-Fang Ping
Research26 Jul 2022
Laboratory Investigation

Volume: 102, P: 1304-1313
A broadband achromatic metalens array for integral imaging in the visible

Zhi-Bin Fan
Hao-Yang Qiu
Jian-Wen Dong
ResearchOpen Access24 Jul 2019
Light: Science & Applications

Volume: 8, P: 1-10
Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling

Xiao-Ning Zhang
Kai-Di Yang
Yi-Fang Ping
ResearchOpen Access08 Jul 2021
Cell Research

Volume: 31, P: 1072-1087
YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML

Ze Chen
Yang-Liu Shao
Xiao-Ning Gao
Research06 May 2021
Oncogene

Volume: 40, P: 3786-3798
Effect of the environment microbiota on the flavour of light-flavour Baijiu during spontaneous fermentation

Xiao-Na Pang
Bei-Zhong Han
Jing-Yu Chen
ResearchOpen Access21 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
A biodegradable thermo-responsive hybrid hydrogel: therapeutic applications in preventing the post-operative recurrence of breast cancer

We prepared a hybrid hydrogel system by doping the gold nanorods (GNRs) into the thermal responsive hydrogel. The near-infrared (NIR) laser was used to trigger the release of loaded Doxorubicin (DOX) by utilizing the photothermal effect of GNRs to induce the contraction of thermo-responsive hydrogels. The development of the hydrogel as the carrier is for the chemo-photothermal co-therapy of local breast cancer recurrence. The DOX-PCNA-GNRs hydrogel effectively prevented breast cancer recurrence after primary tumor resection in a mouse model.

Ying Qu
Bing Yang Chu
Zhi Yong Qian
ResearchOpen Access14 Aug 2015
NPG Asia Materials

Volume: 7, P: e207
Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis

Shao-heng He
Hui-yun Zhang
Ping-chang Yang
Reviews26 Aug 2013
Acta Pharmacologica Sinica

Volume: 34, P: 1270-1283

Search

Reference intervals for coagulation parameters in chinese adults stratified by sex and age

Structures of the ADGRG2–G_s complex in apo and ligand-bound forms

Machine Learning Algorithms for Risk Prediction of Severe Hand-Foot-Mouth Disease in Children

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

A nomogram for predicting T315I-free survival in chronic phase chronic myeloid leukemia patients: a multicenter retrospective study

Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells

Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex

Strategies for an HIV cure: progress and challenges

Neuropeptide Initiated Mast Cell Activation by Transcutaneous Electrical Acupoint Stimulation of Acupoint LI4 in Rats

Pulse Wave Velocity as a Marker of Arteriosclerosis and Its Comorbidities in Chinese Patients

Non-equilibrium synergistic effects in atmospheric pressure plasmas

SLC38A4 functions as a tumour suppressor in hepatocellular carcinoma through modulating Wnt/β-catenin/MYC/HMGCS2 axis

Dicer deficiency impairs proliferation but potentiates anti-tumoral effect of macrophages in glioblastoma

Identification of pimavanserin tartrate as a potent Ca²⁺-calcineurin-NFAT pathway inhibitor for glioblastoma therapy

Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs

Erythromycin suppresses neutrophil extracellular traps in smoking-related chronic pulmonary inflammation

Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium

VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

Ovarian cancer treatment with a tumor-targeting and gene expression-controllable lipoplex

High levels of TIMP1 are associated with increased extracellular matrix stiffness in isocitrate dehydrogenase 1-wild type gliomas

A broadband achromatic metalens array for integral imaging in the visible

Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling

YTHDF2 is a potential target of AML1/ETO-HIF1α loop-mediated cell proliferation in t(8;21) AML

Effect of the environment microbiota on the flavour of light-flavour Baijiu during spontaneous fermentation

A biodegradable thermo-responsive hybrid hydrogel: therapeutic applications in preventing the post-operative recurrence of breast cancer

Mast cells and basophils are essential for allergies: mechanisms of allergic inflammation and a proposed procedure for diagnosis

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