Nature Search

Carrier lifetime enhancement in halide perovskite via remote epitaxy

Crystallographic dislocation has proven harmful to the carrier dynamics in conventional semiconductors but it is unexplored in metal halide perovskites. Here Jiang et al. grow remote epitaxial perovskite films on graphene with density-controlled dislocations and confirm their negative impact.

Jie Jiang
Xin Sun
Jian Shi
ResearchOpen Access12 Sept 2019
Nature Communications

Volume: 10, P: 1-12
A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling

Deng et al. show that endothelial cells respond to high fluid shear stress by KLF2-mediated induction of the BMP–Smad1/5 pathway inhibitor BMPER, resulting in outward vessel remodeling, and apply this knowledge to develop an approach that improves vessel remodeling in mouse models of diabetes.

Hanqiang Deng
Jiasheng Zhang
Martin A. Schwartz
Research08 Jul 2024
Nature Cardiovascular Research

Volume: 3, P: 785-798
Rnd3 protects against doxorubicin-induced cardiotoxicity through inhibition of PANoptosis in a Rock1/Drp1/mitochondrial fission-dependent manner

Wen Ge
Xiaohua Zhang
Dongdong Sun
ResearchOpen Access04 Jan 2025
Cell Death & Disease

Volume: 16, P: 1-16
RETRACTED ARTICLE: REST regulates the cell cycle for cardiac development and regeneration

The mechanisms regulating cardiomyocyte proliferation during development and cardiac regeneration are incompletely understood. The authors show that the transcription factor REST regulates cardiomyocyte proliferation by binding and repressing the cell cycle inhibitor p21.

Donghong Zhang
Yidong Wang
Bin Zhou
ResearchOpen Access07 Dec 2017
Nature Communications

Volume: 8, P: 1-12
CRAT links cholesterol metabolism to innate immune responses in the heart

Mao et al. show that deficiency in CRAT, a key determinant of metabolic flexibility, triggers type I interferon responses and AIM2 inflammasome activation by promoting the bile acid synthesis pathway in cardiomyocytes.

Hua Mao
Aude Angelini
Liang Xie
Research13 Jul 2023
Nature Metabolism

Volume: 5, P: 1382-1394
Evolution of tribo-induced interfacial nanostructures governing superlubricity in a-C:H and a-C:H:Si films

Hydrogenated amorphous carbon is a promising solid lubricant, but the underlying mechanisms surrounding its superlubricity remain unclear. Here the authors reveal that the attainment of a superlubricious state is dependent on the in-situin-situ formation of a nanostructured tribolayer through different carbon rehybridization pathways.

Xinchun Chen
Chenhui Zhang
Jianbin Luo
ResearchOpen Access22 Nov 2017
Nature Communications

Volume: 8, P: 1-13
Ifnar gene variants influence gut microbial production of palmitoleic acid and host immune responses to tuberculosis

Chen et al. show how host genetics influence the abundance of commensal Akkermansia muciniphila in the gut, which in turn produce palmitoleic acid, thus contributing to shaping host immune responses to Mycobacterium tuberculosis infection.

Lingming Chen
Guoliang Zhang
Gucheng Zeng
Research14 Mar 2022
Nature Metabolism

Volume: 4, P: 359-373
Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese

Genetic risk loci for tuberculosis (TB) have so far been identified in African and Russian populations. Here, the authors perform a three-stage GWAS for TB in Han Chinese populations and find two risk loci near ESRRB and TGM6 and further demonstrate that tgm6 protects mice from Mtb infection.

Ruijuan Zheng
Zhiqiang Li
Baoxue Ge
ResearchOpen Access04 Oct 2018
Nature Communications

Volume: 9, P: 1-9
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via osteocalcin expression.

Hua Mao
Luge Li
Xinchun Pi
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-12
Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance

Type 2 diabetes is associated with chronic inflammation and is characterized by insulin resistance. Here, the authors identify a crucial role for endothelial BMPER function in glucose homeostasis, and BMPER overexpression was shown to alleviate insulin resistance and hyperglycemia in diabetic mice.

Hua Mao
Luge Li
Xinchun Pi
ResearchOpen Access26 Mar 2021
Nature Communications

Volume: 12, P: 1-10
Long-term application of fertilizer and manures affect P fractions in Mollisol

Xinchun Lu
Al-Kaisi Mahdi
Wen-xiu Zou
ResearchOpen Access09 Sept 2020
Scientific Reports

Volume: 10, P: 1-12
Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

LDL receptor-related protein 1 (LRP1) is an endocytic receptor involved in cell signalling and energy homeostasis. Here Maoet al. demonstrate that endothelial Lrp1 modulates lipid and glucose metabolism by binding the nuclear receptor Pparγ and promoting its transcriptional activity.

Hua Mao
Pamela Lockyer
Xinchun Pi
ResearchOpen Access10 Apr 2017
Nature Communications

Volume: 8, P: 1-11
MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type

In this study, the authors found that the transcriptional regulator myocyte enhancer binding factor 2 B (MEF2B) is an essential component of the BCL6 gene transcriptional complex and promotes diffuse large B-cell lymphoma (DLBCL) growth by inducing BCL6 expression. In addition to its regulatory role in DLBCL growth, MEF2B expression correlates positively with BCL6 and CD10 expression, and preferentially expressed in the germinal center B-cell-like DLBCL group.

Siraj M. El Jamal
Zakaria Grada
Mohamed Hassan
Research16 Nov 2018
Laboratory Investigation

Volume: 99, P: 539-550
Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis

Zongshan Shen
Jiancheng Wang
Zhengmei Lin
ResearchOpen Access14 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-14
Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense

Wanyan Deng
Quanxin Long
Jianping Xie
ResearchOpen Access25 Apr 2017
Scientific Reports

Volume: 7, P: 1-13
The SOC1-like gene BoMADS50 is associated with the flowering of Bambusa oldhamii

Dan Hou
Ling Li
Xinchun Lin
ResearchOpen Access01 Jun 2021
Horticulture Research

Volume: 8, P: 1-13

Search

Carrier lifetime enhancement in halide perovskite via remote epitaxy

A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling

Rnd3 protects against doxorubicin-induced cardiotoxicity through inhibition of PANoptosis in a Rock1/Drp1/mitochondrial fission-dependent manner

RETRACTED ARTICLE: REST regulates the cell cycle for cardiac development and regeneration

CRAT links cholesterol metabolism to innate immune responses in the heart

Evolution of tribo-induced interfacial nanostructures governing superlubricity in a-C:H and a-C:H:Si films

Ifnar gene variants influence gut microbial production of palmitoleic acid and host immune responses to tuberculosis

Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese

Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance

Long-term application of fertilizer and manures affect P fractions in Mollisol

Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type

Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis

Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense

The SOC1-like gene BoMADS50 is associated with the flowering of Bambusa oldhamii

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