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Author Correction: Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src

Zhenxi Li
Xinghai Yang
Jianru Xiao
Amendments and CorrectionsOpen Access19 Dec 2024
Nature Communications

Volume: 15, P: 1
Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src

The authors of this manuscript identify that Gpr54 activation by its natural ligand Kisspeptin-10 can abrogate bone resorption. Mechanistically, Gpr54 recruits both active Src and the Dusp18 phosphatase, which causes Dusp18 to dephosphorylate Src at Tyr 416.

Zhenxi Li
Xinghai Yang
Jianru Xiao
ResearchOpen Access12 Feb 2024
Nature Communications

Volume: 15, P: 1-17
A Bischler-Napieralski and homo-Mannich sequence enables diversified syntheses of sarpagine alkaloids and analogues

The Mannich reaction is a well-established method for the synthesis of β-amino carbonyl compounds while the analogous reactions of homo-enol or its equivalents with imines or iminium ions are much less explored. Here, the authors describe a homo-Mannich reaction of cyclopropanol with imines generated via a Bischler-Napieralski reaction.

Hanyue Qiu
Xinghai Fei
Min Zhang
ResearchOpen Access09 Sept 2023
Nature Communications

Volume: 14, P: 1-8
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia

Here, the authors provide evidence that SARS-CoV-2 N protein leads to autophagic degradation of Dicer, XPO5, SRSF3, and hnRNPA3, inducing DNA damage and proteotoxic stress, eventually causing pneumonia. The small-molecule drug PJ34 or anastrozole alleviates N protein-induced pneumonia.

Yu-Wei Luo
Jiang-Peng Zhou
Kai-Fu Tang
ResearchOpen Access13 Aug 2024
Nature Communications

Volume: 15, P: 1-23
Frequency-encoded eye tracking smart contact lens for human–machine interaction

Eye tracking techniques enable high-efficient, natural, and effortless human-machine interaction. Here, Zhu et al. proposed a contact lens to track eye movement for wireless eye-machine interaction

Hengtian Zhu
Huan Yang
Fei Xu
ResearchOpen Access27 Apr 2024
Nature Communications

Volume: 15, P: 1-13
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway

REGγ, a proteasome activator, is associated with multiple oncogenic pathways in human cancers and can promote the degradation of multiple proteins including p53. Here the authors highlight a potential role for REGγ in skin cancer and propose a molecular mechanism linking p38 MAPK and Wnt signalling.

Lei Li
Yongyan Dang
Xiaotao Li
Research24 Apr 2015
Nature Communications

Volume: 6, P: 1-9
Sand gradation detection method based on local sampling

Yang Zhang
Danxia Hou
Song Sun
ResearchOpen Access27 Nov 2024
Scientific Reports

Volume: 14, P: 1-15
Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling

Mitochondria are important organelles that generate and respond to signals to maintain cellular homeostasis. Here the authors show that wounding triggers GTPase MIRO-1- and calcium-dependent mitochondrial fragmentation, which aids tissue wound repair through cytochrome P450 and mitochondrial reactive oxygen species.

Hongying Fu
Hengda Zhou
Suhong Xu
ResearchOpen Access26 Feb 2020
Nature Communications

Volume: 11, P: 1-13
Targeting AKT as a promising strategy for SOX2-positive, chemoresistant osteosarcoma

Yujie Liu
Li Kang
Jianru Xiao
ResearchOpen Access24 Feb 2025
Bone Research

Volume: 13, P: 1-13
KDELR1 regulates chondrosarcoma drug resistance and malignant behavior through Intergrin-Hippo-YAP1 axis

Huabin Yin
Dongjie Jiang
Haifeng Wei
ResearchOpen Access23 Dec 2024
Cell Death & Disease

Volume: 15, P: 1-12
Microcontinent subduction and S-type volcanism prior to India–Asia collision

Zongyao Yang
Juxing Tang
Fengqin Ran
ResearchOpen Access21 Jul 2021
Scientific Reports

Volume: 11, P: 1-13
Senolytic cocktail dasatinib and quercetin attenuates chronic high altitude hypoxia associated bone loss in mice

Shen Wang
Juan Zhai
Qinghe Geng
ResearchOpen Access06 Dec 2024
Scientific Reports

Volume: 14, P: 1-13
A dose-escalation study of HP501, a highly selective URAT1 inhibitor, in male Chinese patients with hyperuricemia

Ruilin Ding
Xuehong Deng
Xiaojie Wang
ResearchOpen Access14 Dec 2023
Scientific Reports

Volume: 13, P: 1-11
Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron

Huan Ma
Xinghai Zhang
Tengchuan Jin
ResearchOpen Access29 Jul 2022
Cell Research

Volume: 32, P: 831-842
A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery

Xinghai Zhang
Huajun Zhang
Ailong Huang
ResearchOpen Access30 Aug 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-8
Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

Yi Wu
Yanqiong Shen
Yucai Wang
Correspondence01 Aug 2022
Cell Research

Volume: 32, P: 949-952

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