Nature Search

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

Infection with SARS-CoV-2 causes interstitial pneumonia and viral replication in the lungs of transgenic mice that express a human version of ACE2, confirming the pathogenicity of the virus in this model.

Linlin Bao
Wei Deng
Chuan Qin
Research07 May 2020
Nature

Volume: 583, P: 830-833
Unexpectedly efficient ion desorption of graphene-based materials

Desorption of ions from sorbents generally involves high acid or base concentrations and long desorption times, especially for multivalent ions. Here the authors report a rapid and efficient desorption of Co²⁺, Mn²⁺, and Sr²⁺ adsorbed on magnetite-graphene oxide that occurs by adding low amounts of Al³⁺, which is shown to interact with graphene more strongly than divalent ions.

Xinming Xia
Feng Zhou
Haiping Fang
ResearchOpen Access25 Nov 2022
Nature Communications

Volume: 13, P: 1-7
Non-invasive decision support for NSCLC treatment using PET/CT radiomics

EGFR mutations are common in non-small cell lung cancer and patients with these mutations are treated with tyrosine kinase inhibitors. Here, the authors show that EGFR mutation status can be predicted from ¹⁸F-FDG-PET/CT images, which may enable the stratification of patients for treatment.

Wei Mu
Lei Jiang
Matthew B. Schabath
ResearchOpen Access16 Oct 2020
Nature Communications

Volume: 11, P: 1-11
The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells

Type 1 conventional dendritic cells (cDC1) play a pivotal role in the cross-presentation of antigens, enabling efficient CD8 + T cell response. Here authors show that the transcription factor Zeb1 essentially regulates this process via facilitating the reactive-oxygen-species-dependent rupture of phagosomal membrane to allow antigen export to the cytoplasm.

Yan Wang
Quan Zhang
Nengming Xiao
ResearchOpen Access20 Oct 2023
Nature Communications

Volume: 14, P: 1-20
Micromachined structures decoupling Joule heating and electron wind force

Understanding the impact of the athermal effect on microstructures is crucial for designing and manufacturing semiconductor and metal materials. Here, the authors propose a method using pre-micromachined structures to decouple thermal and athermal effects and experimentally validate its feasibility.

Shaojie Gu
Yasuhiro Kimura
Yuhki Toku
ResearchOpen Access18 Jul 2024
Nature Communications

Volume: 15, P: 1-13
Highly stretchable organic electrochemical transistors with strain-resistant performance

Highly stretchable organic electrochemical transistors with stable charge transport under severe tensional strains are demonstrated using a honeycomb semiconducting polymer morphology, thereby enabling controllable signal output for diverse stretchable bioelectronic applications.

Jianhua Chen
Wei Huang
Antonio Facchetti
Research02 May 2022
Nature Materials

Volume: 21, P: 564-571
A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage

Thioredoxin reductase (TrxR) plays a crucial part in regulating cellular redox homeostasis. Here, the authors developed a fluorescent probe composed of a five-membered disulphide, a coumarin fluorophore and a urea linker that detects TrxR activity with fast response and high selectivity.

Xinming Li
Baoxin Zhang
Jianguo Fang
ResearchOpen Access21 Jun 2019
Nature Communications

Volume: 10, P: 1-12
Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

Two divergent haplotypes from a highly heterozygous lychee genome of the cultivar ‘Feizixiao’ and resequencing of 72 lychee accessions provide insights into the genome evolution and domestication history of lychee.

Guibing Hu
Junting Feng
Jianguo Li
ResearchOpen Access03 Jan 2022
Nature Genetics

Volume: 54, P: 73-83
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions

Zhangjun Fei and colleagues report the draft genome of a Chinese elite watermelon inbred line 97103 and resequencing of 20 diverse accessions that represent the three subspecies of Citrullus lunatus. Comparative genome-wide analyses identify the extent of genetic diversity and population structure of watermelon germplasm.

Shaogui Guo
Jianguo Zhang
Yong Xu
ResearchOpen Access25 Nov 2012
Nature Genetics

Volume: 45, P: 51-58
Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection

Wenkai Ren
Yuexia Liao
Yulong Yin
ResearchOpen Access06 Dec 2018
Mucosal Immunology

Volume: 12, P: 531-544
Correction: Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Chenyang Duan
Lei Kuang
Tao Li
Amendments and CorrectionsOpen Access13 Jan 2025
Cell Death & Disease

Volume: 16, P: 1-4
Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes

Tanglong Yuan
Leilei Wu
Erwei Zuo
ResearchOpen Access20 Feb 2024
Cell Discovery

Volume: 10, P: 1-19
Correction: Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Chenyang Duan
Lei Kuang
Tao Li
Amendments and CorrectionsOpen Access24 Aug 2020
Cell Death & Disease

Volume: 11, P: 1
Erratum: Hybrid graphene tunneling photoconductor with interface engineering towards fast photoresponse and high responsivity

Li Tao
Zefeng Chen
Jian-Bin Xu
Amendments and CorrectionsOpen Access03 Oct 2017
npj 2D Materials and Applications

Volume: 1, P: 1
Formation of nitrogen-containing gas phase products from the heterogeneous (photo)reaction of NO₂ with gallic acid

Heterogeneous reaction of NO₂ with atmospheric humic like substances is a potentially important source of volatile organic compounds, but the role of ubiquitous water-soluble aerosol components in this chemistry remains largely unexplored. Here, secondary electrospray ionization ultrahigh-resolution mass spectrometry is used to obtain real-time measurements of VOCs formed during the heterogeneous reaction of gas phase NO₂ and a solution containing gallic acid as a model for moderately acidic aerosol particles.

Pan Li
Rachel Gemayel
Sasho Gligorovski
ResearchOpen Access16 Sept 2023
Communications Chemistry

Volume: 6, P: 1-10
FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division

Hui Zhang
Yiting Zhao
Xiaofeng Jin
ResearchOpen Access21 Jun 2023
Cell Death & Disease

Volume: 14, P: 1-16
Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Chenyang Duan
Lei Kuang
Tao Li
ResearchOpen Access20 Apr 2020
Cell Death & Disease

Volume: 11, P: 1-19
Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and its potential mechanisms

Yilin Pan
Lu Liu
Manxiang Li
ResearchOpen Access26 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells

Shaojun Li
Yilin Pan
Manxiang Li
ResearchOpen Access20 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Hybrid graphene tunneling photoconductor with interface engineering towards fast photoresponse and high responsivity

Li Tao
Zefeng Chen
Jian-Bin Xu
ResearchOpen Access03 Jul 2017
npj 2D Materials and Applications

Volume: 1, P: 1-8
Rocking-Chair Configuration in Ultrathin Lithium Vanadate-Graphene Hybrid Nanosheets for Electrical Modulation

Haiou Zhu
Xinming Qin
Yi Xie
ResearchOpen Access13 Feb 2013
Scientific Reports

Volume: 3, P: 1-7

Search

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

Unexpectedly efficient ion desorption of graphene-based materials

Non-invasive decision support for NSCLC treatment using PET/CT radiomics

The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells

Micromachined structures decoupling Joule heating and electron wind force

Highly stretchable organic electrochemical transistors with strain-resistant performance

A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage

Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions

Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection

Correction: Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Deep learning models incorporating endogenous factors beyond DNA sequences improve the prediction accuracy of base editing outcomes

Correction: Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Erratum: Hybrid graphene tunneling photoconductor with interface engineering towards fast photoresponse and high responsivity

Formation of nitrogen-containing gas phase products from the heterogeneous (photo)reaction of NO₂ with gallic acid

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and its potential mechanisms

Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells

Hybrid graphene tunneling photoconductor with interface engineering towards fast photoresponse and high responsivity

Rocking-Chair Configuration in Ultrathin Lithium Vanadate-Graphene Hybrid Nanosheets for Electrical Modulation

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