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Showing 1–5 of 5 results
Advanced filters: Author: Yael Gruper Clear advanced filters

  • A large fraction of patients with APS-1 and coeliac disease develop enamel dystrophy, characterized by the presence of autoantibodies against the enamel matrix, which are generated through the breakdown of either central (APS-1) or peripheral (coeliac) tolerance to a battery of ameloblast-sepecific proteins.

    • Yael Gruper
    • Anette S. B. Wolff
    • Jakub Abramson
    Research
    Nature
    Volume: 624, P: 653-662

  • Multiomic analyses of mouse thymic epithelial cells identify several unconventional subsets that are mimetics of various populations of terminally differentiated parenchymal cells and provide insights into their development, molecular features and function.

    • Tal Givony
    • Dena Leshkowitz
    • Jakub Abramson
    Research
    Nature
    Volume: 622, P: 164-172

  • The tumour microenvironment propagates stress responses in resident cells. In tumour-infiltrating natural killer (NK) cells, the HSF1 transcription factor binds to mediators of effector function, negatively regulating NK cytotoxicity. These findings provide important mechanistic insights that may enhance NK cell cancer therapy.

    • Yael Gruper
    • Aviad Ben-Shmuel
    • Ruth Scherz-Shouval
    News & Views
    Nature Cell Biology
    Volume: 26, P: 1630-1631