Nature Search

Long-term engraftment of human stem and progenitor cells for large-scale production of functional immune cells in engineered pigs

Targeted deletion of integrin-associated protein CD47 enhances long-term engraftment of human CD34⁺ cells in immunodeficient pigs lacking IL2RG and RAG2, enabling large-scale production of functional human immune cells.

Zheng Hu
Jun Zou
Yong-Guang Yang
Research20 May 2025
Nature Biomedical Engineering

P: 1-14
Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

Genetic studies of Chinese individuals have been performed, but mostly with short read sequencing, limiting the types of variants that can be identified. Here, the authors perform long read sequencing of 945 han Chinese individuals, finding structural variants under natural selection and those associated with human traits and evolutionary history.

Jiao Gong
Huiru Sun
Shaohua Fan
ResearchOpen Access10 Feb 2025
Nature Communications

Volume: 16, P: 1-21
Displacement and stress response of open-web girders under near field explosive loading

Zongyuan Fan
Kaicong Kuang
Kejian Ma
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-18
Prediction of instability of formwork concrete pier based on big data machine learning for secondary mining without coal pillar mining

Yanhui Zhu
Ye Tian
Tong Zhao
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-23
Copy number variation at the GL7 locus contributes to grain size diversity in rice

Jiayang Li, Xudong Zhu, Qian Qian and colleagues report cloning of the Grain Length on Chromosome 7 (GL7) locus in rice and identify a copy number variant that increases grain length and improves grain quality. They demonstrate how interactions with other grain length–related genes may be used to improve breeding.

Yuexing Wang
Guosheng Xiong
Qian Qian
Research06 Jul 2015
Nature Genetics

Volume: 47, P: 944-948
Projecting future fluid intake of Chinese children in a warming world

Zhu, He, Zhang et al. conduct a cross-sectional study examining the relationship between temperature and fluid intake in Chinese children. Findings reveal a 24 mL daily intake increase per 1 °C temperature rise and projections under climate change scenarios predict substantially higher hydration needs by 2099.

Sui Zhu
Guanhao He
Wenjun Ma
ResearchOpen Access03 Jun 2025
Communications Medicine

Volume: 5, P: 1-10
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

The presentation of systemic lupus erythematosus has been known to differ by ancestry, but the underlying genetic factors remain unclear. Here, the authors report ancestry-specific susceptibility loci and better risk prediction when using data from matched ancestral groups.

Yong-Fei Wang
Yan Zhang
Wanling Yang
ResearchOpen Access03 Feb 2021
Nature Communications

Volume: 12, P: 1-13
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

De novo genome assembly and analyses of 12 maize FILs provide insights into genomic and phenotypic differentiation of various heterotic groups and the molecular basis of heterosis in maize.

Baobao Wang
Mei Hou
Haiyang Wang
Research16 Jan 2023
Nature Genetics

Volume: 55, P: 312-323
Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer

Male breast cancer may involve different populations of immune cells. Here the authors use single cell transcriptomics to show that infiltration of T cells is lower in male breast cancer relative to female breast cancer, and find that this is accompanied by distinct metabolic changes.

Handong Sun
Lishen Zhang
Qiang Ding
ResearchOpen Access11 Sept 2023
Nature Communications

Volume: 14, P: 1-18
Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

Hashimoto’s thyroiditis (HT) is the main cause of hypothyroidism. Here the authors develop a deep learning model for diagnosis of HT on a large multi-site dataset including image and video data.

Qiang Zhang
Sheng Zhang
Xiangchun Li
ResearchOpen Access29 Jun 2022
Nature Communications

Volume: 13, P: 1-8
Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

Rice yield is boosted by overcoming a trait tradeoff.

Xiaoguang Song
Xiangbing Meng
Hong Yu
Research21 Apr 2022
Nature Biotechnology

Volume: 40, P: 1403-1411
Author Correction: De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

Baobao Wang
Mei Hou
Haiyang Wang
Amendments and Corrections02 Feb 2023
Nature Genetics

Volume: 55, P: 355
SLR1 inhibits MOC1 degradation to coordinate tiller number and plant height in rice

Due to reduced gibberellin sensitivity, modern rice cultivars are shorter than traditional varieties but produce more tillers and have higher yields. Here Liao et al. show that gibberellin contributes to decreased tiller number by degrading the MOC1 protein that suppresses bud outgrowth.

Zhigang Liao
Hong Yu
Jiayang Li
ResearchOpen Access21 Jun 2019
Nature Communications

Volume: 10, P: 1-9
Measurement of static and dynamic pupillary characteristics after implantable collamer lens by sirius anterior segment analysis system

Jing Yang
Weiqun Wang
Wentao Liu
ResearchOpen Access13 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
Global mapping reveals increase in lacustrine algal blooms over the past decade

Algal blooms are occurring more frequently, as seen in a global database compiled from satellite imagery from the past few decades.

Xuejiao Hou
Lian Feng
Chunmiao Zheng
Research03 Feb 2022
Nature Geoscience

Volume: 15, P: 130-134
Structured transverse orbital angular momentum probed by a levitated optomechanical sensor

A new polarization structure of light is synthesized in a straightforward and robust way. The light field is probed using a levitated nanoparticle as a sensor. Optical angular momentum is used to control the particle in a novel way, with applications in sensing and quantum optomechanics.

Yanhui Hu
Jack J. Kingsley-Smith
James Millen
ResearchOpen Access06 May 2023
Nature Communications

Volume: 14, P: 1-7
Gain enhanced Fano resonance in a coupled photonic crystal cavity-waveguide structure

Yanhui Zhao
Chenjiang Qian
Xiulai Xu
ResearchOpen Access19 Sept 2016
Scientific Reports

Volume: 6, P: 1-6
Longitudinal wave function control in single quantum dots with an applied magnetic field

Shuo Cao
Jing Tang
Xiulai Xu
ResearchOpen Access27 Jan 2015
Scientific Reports

Volume: 5, P: 1-5
Integrative knowledge-based nitrogen management practices can provide positive effects on ecosystem nitrogen retention

Understanding the general responses of soil gross N cycling to commonly used knowledge-based N management practices on a global scale could help predict ecosystem N retention capacity and subsequent N losses. This global meta-analysis provides evidence for different responses of soil N cycling rates and N losses and associated soil properties to various knowledge-based N management practices.

Ahmed S. Elrys
Jing Wang
Yi Cheng
Research05 Dec 2023
Nature Food

Volume: 4, P: 1075-1089
Demonstration of the quantum principle of least action with single photons

Propagators of single photons based on directly measuring quantum wave functions are experimentally observed. Classical trajectories that satisfy the principle of least action are successfully extracted in the case of free space and harmonic potential.

Yong-Li Wen
Yunfei Wang
Shi-Liang Zhu
Research22 May 2023
Nature Photonics

Volume: 17, P: 717-722
Expanding agroforestry can increase nitrate retention and mitigate the global impact of a leaky nitrogen cycle in croplands

The spatial patterns of global soil potential nitrogen cycling were characterized using 4,032 observations from 398 published studies. The global soil nitrogen cycle shifts from conservative in forests to leaky in croplands, highlighting the importance of forests in the global nitrogen cycle and the need for further insights on nitrate retention in croplands.

Ahmed S. Elrys
Yves Uwiragiye
Christoph Müller
ResearchOpen Access28 Dec 2022
Nature Food

Volume: 4, P: 109-121
Successful use of defibrotide to treat allogeneic hematopoietic stem cell transplantation associated thrombotic microangiopathy in pediatric patients: report from Chinese single center

Jiayu Wang
Yanhui Luo
Sidan Li
Correspondence23 Jul 2024
Bone Marrow Transplantation

Volume: 59, P: 1483-1485
The effects of short-term and long-term air pollution exposure on meibomian gland dysfunction

Ran Hao
Yu Wan
Xuemin Li
ResearchOpen Access25 Apr 2022
Scientific Reports

Volume: 12, P: 1-14
Synthesis of centimeter-size free-standing perovskite nanosheets from single-crystal lead bromide for optoelectronic devices

Jian-Yao Zheng
Hugh G. Manning
John F. Donegan
ResearchOpen Access13 Aug 2019
Scientific Reports

Volume: 9, P: 1-9
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling

Jianxing Yin
Fangshu Ding
Xiefeng Wang
ResearchOpen Access12 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-12
Comparative proteomics in captive giant pandas to identify proteins involved in age-related cataract formation

Yuyan You
Chao Bai
Chenglin Zhang
ResearchOpen Access05 Aug 2023
Scientific Reports

Volume: 13, P: 1-21
Chilling-induced phosphorylation of IPA1 by OsSAPK6 activates chilling tolerance responses in rice

Meiru Jia
Xiangbing Meng
Jiayang Li
ResearchOpen Access26 Jul 2022
Cell Discovery

Volume: 8, P: 1-17
Comparative transcriptome and weighted correlation network analyses reveal candidate genes involved in chlorogenic acid biosynthesis in sweet potato

Jing Xu
Jiahong Zhu
Xiaoning Wang
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-11
Acute effects of 2.856 GHz and 1.5 GHz microwaves on spatial memory abilities and CREB-related pathways

Shengzhi Tan
Hui Wang
Ruiyun Peng
ResearchOpen Access11 Jun 2021
Scientific Reports

Volume: 11, P: 1-10
MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models

Douglas D. Fang
Qiuqiong Tang
Yifan Zhai
ResearchOpen Access03 May 2021
Cell Death Discovery

Volume: 7, P: 1-15
Metabolomics Reveals that Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis in HL-60 and NB-4 Cells

Minjian Chen
Jing Yang
Xiaoling Zhang
ResearchOpen Access16 Jan 2020
Scientific Reports

Volume: 10, P: 1-11
The identification of novel Mycobacterium tuberculosis DHFR inhibitors and the investigation of their binding preferences by using molecular modelling

Wei Hong
Yu Wang
Hao Wang
ResearchOpen Access16 Oct 2015
Scientific Reports

Volume: 5, P: 1-14
HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinoma

Junying Sun
Baocun Sun
Danfang Zhang
ResearchOpen Access22 May 2017
Scientific Reports

Volume: 7, P: 1-13
High efficacy of Azacitidine plus HAG in acute myeloid leukemia: an open-label, single-arm, multi-center, phase 2 study

Jun Li
Qi Han
Zheng Ge
CorrespondenceOpen Access28 Oct 2022
Blood Cancer Journal

Volume: 12, P: 1-5
IPA1 functions as a downstream transcription factor repressed by D53 in strigolactone signaling in rice

Xiaoguang Song
Zefu Lu
Jiayang Li
ResearchOpen Access15 Aug 2017
Cell Research

Volume: 27, P: 1128-1141

Search

Long-term engraftment of human stem and progenitor cells for large-scale production of functional immune cells in engineered pigs

Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

Displacement and stress response of open-web girders under near field explosive loading

Prediction of instability of formwork concrete pier based on big data machine learning for secondary mining without coal pillar mining

Copy number variation at the GL7 locus contributes to grain size diversity in rice

Projecting future fluid intake of Chinese children in a warming world

Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups

Diminishing benefits of urban living for children and adolescents’ growth and development

De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer

Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

Author Correction: De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis

SLR1 inhibits MOC1 degradation to coordinate tiller number and plant height in rice

Measurement of static and dynamic pupillary characteristics after implantable collamer lens by sirius anterior segment analysis system

Global mapping reveals increase in lacustrine algal blooms over the past decade

Structured transverse orbital angular momentum probed by a levitated optomechanical sensor

Gain enhanced Fano resonance in a coupled photonic crystal cavity-waveguide structure

Longitudinal wave function control in single quantum dots with an applied magnetic field

Integrative knowledge-based nitrogen management practices can provide positive effects on ecosystem nitrogen retention

Demonstration of the quantum principle of least action with single photons

Expanding agroforestry can increase nitrate retention and mitigate the global impact of a leaky nitrogen cycle in croplands

Successful use of defibrotide to treat allogeneic hematopoietic stem cell transplantation associated thrombotic microangiopathy in pediatric patients: report from Chinese single center

The effects of short-term and long-term air pollution exposure on meibomian gland dysfunction

Synthesis of centimeter-size free-standing perovskite nanosheets from single-crystal lead bromide for optoelectronic devices

METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling

Comparative proteomics in captive giant pandas to identify proteins involved in age-related cataract formation

Chilling-induced phosphorylation of IPA1 by OsSAPK6 activates chilling tolerance responses in rice

Comparative transcriptome and weighted correlation network analyses reveal candidate genes involved in chlorogenic acid biosynthesis in sweet potato

Acute effects of 2.856 GHz and 1.5 GHz microwaves on spatial memory abilities and CREB-related pathways

MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models

Metabolomics Reveals that Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis in HL-60 and NB-4 Cells

The identification of novel Mycobacterium tuberculosis DHFR inhibitors and the investigation of their binding preferences by using molecular modelling

HMGA2 promotes vasculogenic mimicry and tumor aggressiveness by upregulating Twist1 in gastric carcinoma

High efficacy of Azacitidine plus HAG in acute myeloid leukemia: an open-label, single-arm, multi-center, phase 2 study

IPA1 functions as a downstream transcription factor repressed by D53 in strigolactone signaling in rice

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