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Designing a full-memristive circuit for different algorithm remains a challenge. Here, the authors propose a recirculated logic operation scheme using memristive hardware and 2D transistors for cellular automata, supporting multiple algorithms with a 79-fold cost reduction compared to FPGA.

In the CNS, glutamatergic neurons directly control functional hyperemia via synaptic-like transmission onto arteriolar smooth muscle cells. Inhibiting this process reduces brain atrophy following cerebral ischemia.

Genetic mutations are found in only 15% of sporadic ALS. Here, authors identify PCDHA9 as a candidate ALS gene and elucidate detailed underlying pathogenesis using mice with Pcdhα9 mutations that develop typical ALS phenotype and hallmark pathology.

Design strategies for non-fullerene acceptors are important for achieving high-efficiency organic solar cells. Here the authors design asymmetrically branched alkyl chains on the thiophene unit of the L8-BO acceptor to achieve high crystallinity and photoluminescence quantum yield, yielding over 20% efficiency in single-junction organic solar cells.

Phosphorescence emission from extrinsic rare-earth element and organic component remains a challenge. Here, the authors demonstrate an ultraviolet ultralong intrinsic phosphorescence (UIP, >20,000 seconds) in aluminum nitride (AlN) single-crystal scintillator through X-ray excitation.

The immiscibility of H-He mixtures in gas giants remains poorly understood. Here the authors use large scale machine learning accelerated molecular dynamics simulations to suggest that H-He demixing may occur within large interior radii of Jupiter and Saturn.

Peptides encoded by noncanonical open reading frames play important roles in cancer. Here the authors identify that a microprotein HDSP derived from the long non-coding RNA HOXA10-HOXA9 is overexpressed in gastric cancer and forms a positive feedback loop with MECOM to drive EGFR signaling in gastric cancer progression.

Exciton diffusion length and graded vertical phase separation of the active layer play a critical role in the realization of high-performance thick-film organic solar cells (OSCs). Here, authors demonstrated OSCs with an efficiency of 17.31%, with an active layer thickness of around 300 nm.

The experimental studies to understand the superconductivity of superhydrides remain scarce. Here, the authors report pressure and magnetic field dependence of superconductivity in LaH₁₀, and indicate lattice vibrations strongly affect superconducting coupling.

The morphology of donor–acceptor blends in organic photovoltaics dictates the efficiency of the exciton dissociation and charge diffusion, and thus the final device performance. Here, the authors show that filament assembly helps to maximize the output, further enabling a power conversion efficiency greater than 19%.

Molecular design of acceptor and donor molecules has enabled major progress in organic photovoltaics. Li et al. show that branched alkyl chains in non-fullerene acceptors allow favourable morphology in the active layer, enabling a certified device efficiency of 17.9%.

Polymer-based bulk-heterojunction solar cells have shown some of the highest photoconversion efficiencies in organic photovoltaics, but polymer polydispersity impacts their performance. A small-molecule donor is now reported that enables the fabrication of bulk-heterojunction devices with low acceptor content and photoconversion efficiencies of up to 6.7%.

Northern China contains some of the world’s earliest farming societies. Here, authors use 55 ancient genomes to trace the genetic history of human migrations across northern China for the last 7500 years, and document genetic changes mirroring shifts in subsistence strategy.

The optimization of morphology of active layers for halogen-free solvent processing is essential to enhance performance of organic solar cells. Here, the authors report auxiliary sequential deposition method together with branched-chain-engineered acceptor, realizing device efficiency of over 19%.

Multifunctional all-optical logic gate (AOLG) with broadband-based massively parallel processing is desirable for high-speed optical processor. Here, authors propose a reconfigurable all-in-one ultra-broadband AOLG with experimentally achieving 9 fundamental Boolean logics in a single configuration.

CO₂ electroreduction to multicarbon products is desirable but challenging. Now, self-pressurizing nanoscale capsule catalysts are synthesized. The self-pressurising capsules harness high-pressure CO environments for selective acetate or propanol production via a CO–CO₂ coupling pathway.

Polymeric nitrogen has yet to be recovered to ambient conditions, precluding its practical application as high-energy density material. Here, the authors highlight a possible route to the formation of a tetragonal polymeric nitrogen via helium-nitrogen compounds at high pressures.

Non-fullerene acceptors are crucial for realising efficient charge transport and high power conversion in organic solar cells, yet the relationship of molecular packing and carrier transport is not well-understood. Here, the authors study the effect of side-chain engineering on the backbone assembly and the corresponding charge transport pathway.

Organic solar cells based on non-fullerene acceptors have enabled high efficiencies yet their charge dynamics and its impact on the photovoltaic parameters are not fully understood. Now, Chen et al. provide a general description of non-radiative voltage losses in both fullerene and non-fullerene solar cells.

Reliably controlling the morphology in organic solar cells is desired for up-scaling. Here Weng et al. combine the advantages of the fibril network donor and the state of the art Y6 acceptor in a two-step approach to deliver a high efficiency of 16% without batch-to-batch variation.

A general method for the synthesis of high-purity crystals of metastable 1T′-phase transition metal dichalcogenides is reported, providing a source of phase-engineered materials that can be used to systematically explore their intrinsic properties.

Organic semiconductors with high mobility and strong fluorescence are necessary for optoelectronic devices. Here, Liu et al. show an organic semiconductor, 2,6-diphenylanthracene, satisfying both requirements with mobility of 34 cm² V⁻¹ s⁻¹ and emission of 6,627 cd m⁻²at a turn-on voltage of 2.8 V.

The protein tyrosine kinase c-Src is a renowned proto-oncogene with pleiotropic effects. Here, the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases HK1 and HK2, which in turns lead to increased HK catalytic activity and consequent enhancement of glycolysis.

Solid-state cracking in additive manufacturing is often caused by residual stress. Here, controlling the thermal history and cooling rate of a AlCrFe₂Ni₂ high-entropy alloy during laser additive manufacturing promotes the formation of a face-centered cubic phase, which can accommodate residual stress and prevent cracking.

Ding Ma, Xing Xie, Yongyong Shi and colleagues report a genome-wide association study of cervical cancer in the Han Chinese population. They identify two new susceptibility lociat 4q12 and 17q12.

Alternative splicing profiles of human pancreatic islets at single-cell resolution define endocrine cell types and reveal the dysregulated splicing programs in β-cell maturation in type 2 diabetes pathogenesis.