Nature Search

Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation

Impaired mitochondrial long-chain fatty acid β-oxidation (mtLCFAO) in type 2 alveolar epithelial (AT2) cells is thought to aggravate alveolar inflammation in acute lung injury. Here, the authors show that the mtLCFAO rate limiting enzyme CPT1a is decreased in AT2 cells in acute respiratory distress syndrome, highlighting the role of mtLCFAO in immunometabolism in this context.

Kuei-Pin Chung
Chih-Ning Cheng
Chong-Jen Yu
ResearchOpen Access22 Aug 2024
Nature Communications

Volume: 15, P: 1-23
NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish

Yen-Lin Chen
Brian Hon-Yin Chung
Ni-Chung Lee
ResearchOpen Access01 Mar 2025
Cell Death Discovery

Volume: 11, P: 1-11
Electric-field control of the nucleation and motion of isolated three-fold polar vertices

Despite various known topological polar structures, the dynamic property of isolated ones is still poorly understood. Here, the authors show the controlled nucleation and ability to move of isolated three-fold vertices under an applied electric field.

Mingqiang Li
Tiannan Yang
Peng Gao
ResearchOpen Access25 Oct 2022
Nature Communications

Volume: 13, P: 1-8
Long-term follow-up of osteomyelitis caused by Bacille Calmette-Guérin vaccination in immunocompetent children

Yen-Lin Tsai
Yen-Ju Chen
Yu-Cheng Lai
ResearchOpen Access05 Mar 2020
Scientific Reports

Volume: 10, P: 1-8
Deterministic optical control of room temperature multiferroicity in BiFeO₃ thin films

The remote, non-volatile and reversible optical control of ferroic orders is challenging. Here, using laser illumination, multiple orders in epitaxial mixed-phase BiFeO₃ are manipulated deterministically using a thermally driven flexoelectric effect.

Yi-De Liou
Yu-You Chiu
Jan-Chi Yang
Research06 May 2019
Nature Materials

Volume: 18, P: 580-587
Complex strain evolution of polar and magnetic order in multiferroic BiFeO₃ thin films

To fully exploit the potential of multiferroic materials the control of their intrinsic degrees of freedom is a prerequisite. Here, the control of spin orientation in strained BiFeO₃ films is demonstrated elucidating the microscopic mechanism of the complex interplay of polar and magnetic order.

Zuhuang Chen
Zhanghui Chen
Lane W. Martin
ResearchOpen Access21 Sept 2018
Nature Communications

Volume: 9, P: 1-9
Polygenic height prediction for the Han Chinese in Taiwan

Chih-Hao Chang
Che-Yu Chou
Pui-Yan Kwok
ResearchOpen Access05 Feb 2025
npj Genomic Medicine

Volume: 10, P: 1-10
Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors

Bleeding complications limits the use of effective antithrombotics therapeutics. Here, the authors developed next-generation direct thrombin inhibitors with low bleeding risks as safe peri-percutaneous coronary intervention anticoagulants when used in combination with antiplatelets.

Cho Yeow Koh
Norrapat Shih
Mark Y. Chan
ResearchOpen Access25 Nov 2021
Nature Communications

Volume: 12, P: 1-16
The role of lattice dynamics in ferroelectric switching

Reducing the switching energy of ferroelectric films remains an important goal. Here, the authors elucidate the fundamental role of lattice dynamics in ferroelectric switching on both freestanding BiFeO₃ membranes and films clamped to a substrate.

Qiwu Shi
Eric Parsonnet
Ramamoorthy Ramesh
ResearchOpen Access02 Mar 2022
Nature Communications

Volume: 13, P: 1-10
The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC

Huai-Cheng Huang
Yen-Lin Huang
Pei-Jen Lou
ResearchOpen Access02 Oct 2024
Oncogenesis

Volume: 13, P: 1-10
Possible absence of critical thickness and size effect in ultrathin perovskite ferroelectric films

Understanding ferroelectricity at reduced dimensions will be important for future sub-nanoscale devices based on ferroelectrics. Using high resolution electron microscopy; Gaoet al., observe the existence of a measurable polarization at a thickness of just 1.5-unit cells

Peng Gao
Zhangyuan Zhang
Yuichi Ikuhara
ResearchOpen Access06 Jun 2017
Nature Communications

Volume: 8, P: 1-8
Reappraisal of effects of serum chemerin and adiponectin levels and nutritional status on cardiovascular outcomes in prevalent hemodialysis patients

Hung-Yuan Chen
Yen-Lin Chiu
Yu-Sen Peng
ResearchOpen Access26 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Deep convolutional neural network-based algorithm for muscle biopsy diagnosis

The authors developed a deep convolutional neural network-based algorithm to support pathological muscle diagnosis. The algorithm differentiated idiopathic inflammatory myopathies and outperformed nine human physicians under limited diseases and conditions. These results suggest that the algorithm has the potential to be used directly in clinical settings.

Yoshinori Kabeya
Mariko Okubo
Ichizo Nishino
Research02 Oct 2021
Laboratory Investigation

Volume: 102, P: 220-226
Clinicopathologic characteristics of poorly differentiated chordoma

Angela R. Shih
Gregory M. Cote
Yen-Lin Chen
Research26 Feb 2018
Modern Pathology

Volume: 31, P: 1237-1245
Anisotropic superconductivity induced by periodic multiferroic ___domain patterns

The periodic ___domain pattern of BiFeO₃ enables the anisotropic superconductivity in YBa₂Cu₃O_7 − x. In this work, we introduce a design of periodic multiferroic ___domain patterns to create the anisotropic superconductivity. High T_C can be found when we measured the resistance parallel to the ___domain wall direction and the broader transition with lower T_C is found to be perpendicular to the ___domain walls. (a) and (b) the resistance versus temperature in YBa₂Cu₃O_7 − x/BiFeO₃ heterostructures with two different ___domain patterns 109° and 71°, respectively.

Yen-Lin Huang
Bo-Chao Huang
Ying-Hao Chu
ResearchOpen Access06 Dec 2019
NPG Asia Materials

Volume: 11, P: 1-8
The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research

A framework of patient-partnered research allows patients with angiosarcoma to share their samples and clinical records securely to accelerate molecular characterization of tumors and identification of therapeutic approaches.

Corrie A. Painter
Esha Jain
Nikhil Wagle
Research10 Feb 2020
Nature Medicine

Volume: 26, P: 181-187
MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

Christopher E. Lietz
Cassandra Garbutt
Dimitrios Spentzos
ResearchOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1-15
nNOS-positive minor-branches of the dorsal penile nerves is associated with erectile function in the bilateral cavernous injury model of rats

Yen-Lin Chen
Ting-Ting Chao
Han-Sun Chiang
ResearchOpen Access17 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Phosphate Removal in Relation to Structural Development of Humic Acid-Iron Coprecipitates

Kai-Yue Chen
Liang-Ching Hsu
Yu-Ting Liu
ResearchOpen Access09 Jul 2018
Scientific Reports

Volume: 8, P: 1-10
Author Correction: Predictive Value of Serum Gamma-glutamyltranspeptidase for Future Cardiometabolic Dysregulation in Adolescents- a 10-year longitudinal study

Chien-Ming Lin
Chang-Hsun Hsieh
Yen-Lin Chen
Amendments and CorrectionsOpen Access13 Nov 2018
Scientific Reports

Volume: 8, P: 1-2
NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish

Chi-Hwa Yang
Yu-Jung Yeh
Yi-Rong Chen
ResearchOpen Access12 Jul 2017
Scientific Reports

Volume: 7, P: 1-9
Aqueous extract of Sapindus mukorossi induced cell death of A549 cells and exhibited antitumor property in vivo

Min Liu
Yen-Lin Chen
Chia-Ching Liao
ResearchOpen Access19 Mar 2018
Scientific Reports

Volume: 8, P: 1-15
PTBP1-mediated regulation of AXL mRNA stability plays a role in lung tumorigenesis

Chun-Yu Cho
Shih-Ying Chung
Shuang-En Chuang
ResearchOpen Access15 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma

Shao-Ming Wang
Wen-Chi Lin
Ju-Ming Wang
ResearchOpen Access12 Jan 2021
Cell Death Discovery

Volume: 7, P: 1-11
Integration of amorphous ferromagnetic oxides with multiferroic materials for room temperature magnetoelectric spintronics

Humaira Taz
Bhagwati Prasad
Ramki Kalyanaraman
ResearchOpen Access27 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma

Wen-Chin Weng
Kuan-Hung Lin
Hsinyu Lee
ResearchOpen Access11 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
Predictive Value of Serum Gamma-glutamyltranspeptidase for Future Cardiometabolic Dysregulation in Adolescents- a 10-year longitudinal study

Chien-Ming Lin
Chang-Hsun Hsieh
Yen-Lin Chen
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma

Huan-Hsien Kuo
Ruey-Jen Lin
Alice L. Yu
ResearchOpen Access07 Sept 2017
Scientific Reports

Volume: 7, P: 1-13

Search

Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation

NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish

Electric-field control of the nucleation and motion of isolated three-fold polar vertices

Long-term follow-up of osteomyelitis caused by Bacille Calmette-Guérin vaccination in immunocompetent children

Deterministic optical control of room temperature multiferroicity in BiFeO₃ thin films

Complex strain evolution of polar and magnetic order in multiferroic BiFeO₃ thin films

Polygenic height prediction for the Han Chinese in Taiwan

Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors

The role of lattice dynamics in ferroelectric switching

The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC

Possible absence of critical thickness and size effect in ultrathin perovskite ferroelectric films

Reappraisal of effects of serum chemerin and adiponectin levels and nutritional status on cardiovascular outcomes in prevalent hemodialysis patients

Deep convolutional neural network-based algorithm for muscle biopsy diagnosis

Clinicopathologic characteristics of poorly differentiated chordoma

Anisotropic superconductivity induced by periodic multiferroic ___domain patterns

The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

nNOS-positive minor-branches of the dorsal penile nerves is associated with erectile function in the bilateral cavernous injury model of rats

Phosphate Removal in Relation to Structural Development of Humic Acid-Iron Coprecipitates

Author Correction: Predictive Value of Serum Gamma-glutamyltranspeptidase for Future Cardiometabolic Dysregulation in Adolescents- a 10-year longitudinal study

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish

Aqueous extract of Sapindus mukorossi induced cell death of A549 cells and exhibited antitumor property in vivo

PTBP1-mediated regulation of AXL mRNA stability plays a role in lung tumorigenesis

CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma

Integration of amorphous ferromagnetic oxides with multiferroic materials for room temperature magnetoelectric spintronics

VEGF expression correlates with neuronal differentiation and predicts a favorable prognosis in patients with neuroblastoma

Predictive Value of Serum Gamma-glutamyltranspeptidase for Future Cardiometabolic Dysregulation in Adolescents- a 10-year longitudinal study

High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma

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