This study presents an ultradeep analysis of the N-glycoproteome in mouse tissues, establishing the largest dataset to date. The resource enhances AI models for glycopeptide prediction, provides insights into tissue-specific glycosylation patterns, and reveals distinct pathological signatures in neurodegenerative diseases. To facilitate access to mouse and human N-glycoproteome, the authors establish a comprehensive database resource N-GlycoMiner.
- Pan Fang
- Xiangming Yu
- Huali Shen
