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Showing 1–4 of 4 results

Advanced filters: Author: Yize Mao Clear advanced filters

Multimodal single cell-resolved spatial proteomics reveal pancreatic tumor heterogeneity

The integration of antibody-guided cell typing and mass spectrometry-based proteomics remains challenging. Here, the authors develop Spatial and Cell-type Proteomics (SCPro), a multimodal spatial proteomics approach for profiling tissue proteome heterogeneity.

Yanfen Xu
Xi Wang
Ruijun Tian
ResearchOpen Access21 Nov 2024
Nature Communications

Volume: 15, P: 1-18
AhR diminishes the efficacy of chemotherapy via suppressing STING dependent type-I interferon in bladder cancer

An effective response to chemotherapy is often associated with the promotion of type-I interferons and anti-tumor immune responses. Here the authors show that tryptophan metabolites induced by chemo-drugs interfere with STING activation and IFN-I production in bladder cancer, reducing the efficacy of chemotherapy.

Zikun Ma
Zhiyong Li
Xiaoyu Liang
ResearchOpen Access05 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Genetic approach uncovering the pathways between childhood maltreatment and suicide attempt

Diyang Qu
Xu Zhang
Runsen Chen
Research26 Apr 2025
Molecular Psychiatry

P: 1-11
Epidemiology of mental health problems among patients with cancer during COVID-19 pandemic

Yuanyuan Wang
Zhizhou Duan
Runsen Chen
ResearchOpen Access31 Jul 2020
Translational Psychiatry

Volume: 10, P: 1-10

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